Sensor and method for sensing the concentration of a component in a medium

• US 5,120,510 A
• Filed: 12/06/1990
• Issued: 06/09/1992
• Est. Priority Date: 10/10/1986
• Status: Expired due to Term

• Current Assignee: Terumo Cardiovascular Systems Corporation (Terumo Corporation)
• Original Assignee: Minnesota Mining and Manufacturing Co (3M Company)
• Inventors: Maxwell, Thomas P., Gourley, Ted H., Hacker, Thomas G., Yafuso, Masao, Miller, William W.
• Primary Examiner(s): Johnston, Jill A.
• Application Number:
  US07/624,200
• Time in Patent Office: 551 Days
• Field of Search: 422/82.06, 422/82.07, 436/68, 436/165, 385/12, 128/634
• US Class Current: 422/82.07
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: G01N 2021/6434 Optrodes
• CPC Class Codes: G01N 2021/6439 with indicators, stains, dyes, tags, labels, marks
• CPC Class Codes: G01N 2021/772 Tip coated light guide
• CPC Class Codes: G01N 2021/773 Porous polymer jacket; Polymer matrix with indicator
• CPC Class Codes: G01N 2021/7786 Fluorescence
• CPC Class Codes: G01N 21/7703 using reagent-clad optical fibres or optical waveguides using measurement of total internal reflection or attenuated total reflection G01N21/552; optical fibres or waveguides per se G02B
• CPC Class Codes: G01N 21/80 Indicating pH value
• CPC Class Codes: G01N 21/81 Indicating humidity
• CPC Class Codes: G01N 31/223 for investigating presence of specific gases or aerosols G01N31/221, G01N31/222 take precedence; actuation of fire alarm by presence of smoke or gases G08B17/10

Abstract

An apparatus for sensing the concentration of a component such as oxygen in a medium such as blood. The apparatus includes an elongated signal transmitter and a sensing element at one end thereof. A substantially rigid sleeve is secured around such end to provide a pocket for the sensing element.

Claims

1. An apparatus for sensing the concentration of a component in blood comprising:

sensor means comprising at least one indicator for providing a signal which varies in response to the concentration of a component in blood, and a component permeable, solid polymeric matrix containing said indicator, said sensor means being sized so as to be capable of being positioned within a blood vessel of a patient;

elongated signal means having a distal end at or near which said sensor means is located, and elongated signal means acting to transmit a signal from said sensor means; and

sleeve means more rigid than said elongated signal means, said sleeve means being secured to said elongated signal means and extending distally of said distal end of said elongated signal means to at least partially define a pocket in which said sensor means is located, said sleeve means extending around the entire circumference of at least a portion of said sensor means, said sleeve means acting to reduce the possibility of relative movement between said sensor means and said distal end of said elongated signal means.

2. The apparatus of claim 1 wherein said sleeve means is substantially rigid.

3. The apparatus of claim 1 wherein said sleeve means extends distally of said distal end of said elongated signal means a distance of in the range of about 0.5 to 2 times the maximum transverse dimension of said distal end of said elongated signal means.

4. The apparatus of claim 3 wherein said sleeve means is substantially rigid.

5. The apparatus of claim 1 which further comprises adhesive means acting to adhesively secure said sleeve means to said elongated signal means.

6. The apparatus of claim 5 wherein said indicator is an optical indicator and said adhesive means includes additional optical indicator and acts to provide said additional optical indicator to said sensor means.

7. The apparatus of claim 1 wherein said elongated signal means is an optical fiber.

8. The apparatus of claim 7 wherein said optical fiber acts to transmit signals to and from said sensor means.

9. The apparatus of claim 8 which further comprises a light source for transmitting light signals through said optical fiber to said sensor means and a light receiver for receiving light signals from said sensor means through said optical fiber.

10. The apparatus of claim 1 wherein said sleeve means further acts to increase the apparent stiffness of at least one of said distal portion of said elongated signal means and said sensor means.

11. The apparatus of claim 1 wherein said sleeve means is made of glass.

12. The apparatus of claim 1 which further comprises overcoating means acting to at least partially cover said sensor means.

13. The apparatus of claim 12 wherein said overcoating means comprises a medium insoluble, component permeable polymeric material and an effective amount of an opaque agent.

14. The apparatus of claim 12 wherein said indicator is a fluorescence indicator and said overcoating means comprises a water insoluble, component permeable, cross-linked cellulosic material.

15. The apparatus of claim 1 wherein said indicator is an optical indicator.

16. The apparatus of claim 15 wherein said optical indicator is selected from the group consisting of fluorescence indicators.

17. The apparatus of claim 1 wherein said elongated signal means is further capable of delivering a source signal to said sensor means.

18. The apparatus of claim 17 wherein said elongated signal means is an optical fiber.

19. The apparatus of claim 1 wherein said pocket is substantially filled with said solid polymeric matrix containing said indicator.