Temperature controlled RF coagulation

• US 5,122,137 A
• Filed: 04/27/1990
• Issued: 06/16/1992
• Est. Priority Date: 04/27/1990
• Status: Expired due to Term

• Current Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Corporation
• Inventors: Lennox, Charles D.
• Primary Examiner(s): Pellegrino, Stephen C.
• Assistant Examiner(s): SHUMAKER, STEVEN
• Application Number:
  US07/515,850
• Time in Patent Office: 781 Days
• Field of Search: 606/33-40, 606/41, 606/47, 128/736, 128/804, 128/399-401
• US Class Current: 606/40
• CPC Class Codes: A61B 18/1206 Generators therefor
• CPC Class Codes: A61B 18/1402 Probes for open surgery
• CPC Class Codes: A61B 18/1442 Probes having pivoting end effectors, e.g. forceps
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2017/00084 Temperature
• CPC Class Codes: A61B 2017/00274 Prostate operation, e.g. prostatectomy, turp, bhp treatment
• CPC Class Codes: A61B 2017/00292 mounted on or guided by flexible, e.g. catheter-like, means
• CPC Class Codes: A61B 2017/4233 Operations on Fallopian tubes, e.g. sterilization A61B2017/1125 takes precedence
• CPC Class Codes: A61B 2018/00357 Endocardium
• CPC Class Codes: A61B 2018/00547 Prostate
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00726 Duty cycle
• CPC Class Codes: A61B 2018/00791 Temperature
• CPC Class Codes: A61M 2205/32 with radio-opaque indicia
• CPC Class Codes: A61M 2230/04 Heartbeat characteristics, e.g. ECG, blood pressure modulation

Abstract

Radiofrequency medical devices for ohmic heating of tissue of a patient include a temperature sensor carried by and in thermally conductive relationship with a thermally conductive electrode. The sensor is connected for feedback to a control circuit that modulates RF power applied to the electrode according to the signal received from the temperature sensor. The control circuit and RF power supply alternate between two operating modes. In the first mode the RF power supply applies RF power to the electrode. In the second mode the control circuit senses a signal from the temperature sensor in the absence of RF signal. The control circuit compares the signal from the temperature sensor to a set value and modulates the RF power applied to the electrode in accordance with the set value.

Claims

1. A method of ohmic heating of tissue of a patient in order to induce coagulation, comprising the steps of

selecting a temperature at which target tissue is to be coagulated through flow of RF current through tissue disposed between a thermally conductive, tissue-engaging electrode and at least one other patient-contacting RF conductor, said selected temperature being a maximum temperature consistent with avoiding detrimental sticking of the electrode to the tissue directly engaged by the electrode and avoiding undesired desiccation of tissue,

repeatedly switching between a power on mode and a power off mode,

during said power on mode, applying RF power to said electrode and said at least one other conductor in order to cause RF current of a frequency in the range of about 100 kilohertz to 100 megahertz to flow between said electrode and said at least one other conductor for tissue-coagulation, said thermally conductive, tissue-engaging electrode concentrating RF current in a local region of the patient'"'"'s tissue in the vicinity of said electrode,

during said power off mode, sensing, by means of a temperature sensor carried by and in thermally conductive relationship with said thermally conductive, tissue-engaging electrode, the temperature of said electrode in the absence of RF signal, thereby to sense indirectly the temperature of tissue contacted directly by the electrode, said temperature sensor having a greater accuracy in the absence of interfering RF electrical noise caused by said RF current passing through said thermally conductive electrode than in the presence of said interfering RF electrical noise,

comparing said sensed temperature to said selected, maximum temperature,

modulating said Rf power applied to said electrode in accordance with comparison of said sensed temperature and said selected, maximum temperature, and

coagulating said target tissue at said selected, maximum temperature as said modulated RF current flows between said electrode and said at least one other conductor during said power on mode.

2. The method of claim 1 wherein said temperature sensor is a thermistor.

3. The method of claim 1 wherein the period of temperature sensing is of the order of 1 percent of the cycle time.

4. The method of claim 1 wherein said at least one other conductor is a patient grounding plate.

5. The method of claim 1 wherein said thermally conductive, tissue-contacting electrode and said at least one other patient-contacting RF conductor comprise opposed electrodes each of which has a localized contact with the tissue of said patient.

6. The method of claim 5 wherein said electrodes are mounted on opposing jaws of a forceps, and said method further comprises the step of grasping tissue between said opposing jaws of said forceps.

7. The method of claim 5 or 6 wherein said step of sensing temperature comprises sensing the temperature of each of said electrodes.

8. The method of claim 7 wherein said step of modulating said RF power is performed in accordance with the higher temperature sensed during said step of sensing the temperature of each of said electrodes.

9. The method of claim 1 wherein said temperature sensor comprises a thermocouple.

10. The method of claim 1 wherein said thermally conductive, tissue-engaging electrode is mounted on a gastro-intestinal hemostasis probe, said method further comprises the step of inserting said gastro-intestinal hemostasis probe into the gastro-intestinal tract of said patient, and said step of coagulating said target tissue comprises inducing gastro-intestinal hemostasis.

11. The method of claim 1 wherein said thermally conductive, tissue-engaging electrode is located on a surgical hemostasis probe, said method further comprises the step of applying said surgical hemostasis probe to the body of said patient at a location at which surgery is being performed, and said step of coagulating said target tissue comprises inducing hemostasis in the vicinity of said surgical probe.

12. The method of claim 1 wherein said thermally conductive, tissue-engaging electrode is located on a guidewire probe.

13. The method of claim 12 wherein

said electrode comprises a tip of said guidewire probe,

said guidewire probe is coated with insulation except at said electrode tip of said probe,

said thermistor is mounted within said tip of said guidewire probe

said method further comprises the step of inserting said guidewire probe into a duct in said patient'"'"'s body, and

said step of coagulating said target tissue results in thermal occlusion of said duct.

14. The method of claim 13 wherein said duct is a seminal duct and said step of coagulating said target tissue results in thermal occlusion of said seminal duct.

15. The method of claim 13 wherein said duct is a fallopian tube and said step of coagulating said target tissue comprises thermal occlusion of said fallopian tube.

16. The method of claim 1 wherein said thermally conductive, tissued-engaging electrode is located on a needle.

17. The method of claim 16 wherein

said electrode comprises a tip of said needle,

said method further comprises the step of passing said needle through the skin of said patient,

and said step of coagulating said target tissue comprises percutaneously inducing coagulation treatment of a liver metastasis.

18. The method of claim 17 wherein

said electrode comprises a tip of said needle,

and said step of coagulating said target tissue comprises inducing coagulation treatment of a prostatic tumor.

19. The method of claim 1 wherein said thermally conductive, tissue-engaging electrode is mounted on a thermal ablation probe, said method further comprises the steps of sensing electrical impulses from the heart using at least one electro-physiology electrode mounted on said thermal ablation probe and positioning said electrode at the location of a source of arrythmia, and said step of coagulating said target tissue comprises inducing coagulation of said location of said source of arrythmia.

20. The method of claim 1 wherein

said step of applying RF power to said electrode and said at least one other conductor is performed by an RF power supply having one pole connected to said electrode and a second pole connected to said at least one other conductor,

and said steps of comparing said sensed temperature to said selected, maximum temperature and modulating said RF power applied to said electrode are performed by a control circuit connected to said temperature sensor and constructed to modulate RF power applied to said electrode according to the signal received from said temperature sensor.

21. The method of claim 1 wherein

said step of selecting said maximum temperature comprises setting a reference signal,

and said step of modulating said RF power to said electrode comprises causing said temperature of said electrode to approach a temperature represented by said reference signal, thereby to control the temperature of said electrode and consequently the temperature of tissue contacted by the electrode.