Optical probe

• US 5,124,130 A
• Filed: 05/22/1990
• Issued: 06/23/1992
• Est. Priority Date: 05/22/1990
• Status: Expired due to Term

• Current Assignee: Camino Neurocare, Inc.
• Original Assignee: Optex Biomedical, Inc.
• Inventors: Costello, David J., Schlain, Leslie A., Singh, Raghuvir, Salter, James R., Kosa, Nadhir B.
• Primary Examiner(s): WARDEN, JILL ALICE
• Application Number:
  US07/526,822
• Time in Patent Office: 763 Days
• Field of Search: 422/82.06, 422/82.11, 422/82.07, 356/402, 356/409-411, 385/12, 385/13, 436/68, 436/136, 436/133, 436/163, 128/634
• US Class Current: 422/82.06
• CPC Class Codes: G01N 2021/7706 Reagent provision
• CPC Class Codes: G01N 2021/7793 Sensor comprising plural indicators
• CPC Class Codes: G01N 21/7703 using reagent-clad optical fibres or optical waveguides using measurement of total internal reflection or attenuated total reflection G01N21/552; optical fibres or waveguides per se G02B
• CPC Class Codes: G02B 6/04 formed by bundles of fibres G02B6/24 takes precedence
• CPC Class Codes: G02B 6/362 Vacuum holders for optical elements
• CPC Class Codes: G02B 6/40 having fibre bundle mating means
• CPC Class Codes: Y10T 436/204998 Inorganic carbon compounds
• CPC Class Codes: Y10T 436/207497 Molecular oxygen

Abstract

Method for making a probe with a plurality (one or more) of optical fiber sensors containing colorimetric chemical indicators in gaps in the fibers, the fibers bent to provide good light transmission qualities. Apparatus for making a probe with a plurality of such optical fiber sensors. A probe with a plurality of such optical fiber sensors. A vacuum chuck for holding the ends of such fibers.

Claims

1. An integral optical fiber sensor probe comprising

a plurality of optical fibers for transmitting light, at least two of the optical fibers having a fiber bend therein,

the fiber bends and a portion of the fibers adjacent the fiber bends encapsulated within cured potting encapsulant material forming a solid integral probe body which is generally tubular along its length and having a diameter across its length,

a plurality of sample chambers formed in the cured potting encapsulant material of the solid integral probe body, each sample chamber defined by side walls and a bottom wall and having an open portion,

each sample chamber disposed between two opposed fiber faces of optical fibers opposite each other on opposite sides of the sample chamber, one of said two opposed fiber faces being a face of one of the optical fibers having a fiber bend therein, light transmitted through one of the optical fibers passing through the sample chamber from one fiber face to the other,

each sample chamber containing a chemical indicating material covering the two opposed fiber faces, the chemical indicating material for changing in response to a specific chemical passing into the sample chamber through the open portion of the sample chamber so that light is changed which is transmitted from one opposed fiber face and through changed chemical indicating material to the other fiber face, and

the portions of the fibers adjacent the fiber bends and the fiber bends spaced apart from each other in the solid integral probe body.

2. The probe of claim 1 wherein the generally tubular solid integral probe body is between 600 microns and 700 microns in diameter.

3. The probe of claim 1 comprising also a selective membrane disposed over each open portion of each sample chamber, the membrane for selectively permitting the specific chemical to pass through the membrane to the chemical indicating material.

4. The probe of claim 1 wherein

the plurality of optical fibers is three optical fibers,

the plurality of sample chambers is three sample chambers, one sample chamber formed to intersect each of the three optical fibers, and

the sample chambers are spaced apart along the probe body by a longitudinal distance ranging between 665 microns to 915 microns.

5. The probe of claim 4 wherein the sample chambers are spaced apart along the probe body by a longitudinal distance of 790 microns.

6. The probe of claim 1 wherein

the solid integral probe body has a distal tip, and

a first sample chamber is spaced apart along the probe body from the distal tip a longitudinal distance ranging between 2240 microns and 2840 microns.

7. The probe of claim 6 wherein the first sample chamber is about 2540 microns from the distal tip of the probe.

8. The probe of claim 1 wherein the sample chambers are generally five-sided having length, width, and depth and

the length ranging between 85 microns and 115 microns,

the width ranging between 130 microns and 160 microns and

the depth ranging between 130 microns and 160 microns,

9. The probe of claim 1 wherein the length of the sample chambers is 100 microns and the width of the sample chambers is 145 microns.

10. The probe of claim 1 wherein

the probe body is 650 microns or less in diameter.

11. The probe of claim 1 wherein there are three sample chambers, one related to each optical fiber, one sample chamber containing a pH indicator, one sample chamber containing an oxygen indicator, and one sample chamber containing a carbon dioxide indicator.

12. The probe of claim 1 including also a thermocouple with a metal bead in an end of the probe body and two metal leads extending from the end of the probe body with ends of the optical fibers.

13. The probe of claim 12 wherein the thermocouple is disposed more centrally in the probe than are the optical fibers.

14. The probe of claim 1 including also

a plastic connector secured to the probe, the connector for facilitating introduction of the probe into an intra-arterial cannula, the connector having a separate channel that permits fluids to be taken from or introduced into the cannula while the probe is in place within the cannula,

a tubing harness connected to the connector for protecting and containing a portion of the optical fibers of the probe,

a junction box to which the tubing harness extends and with which the tubing harness is interconneted,

a sensor interface unit for providing light input to the probe and detecting and measuring light coming out of the probe, the optical fibers extending from the junction box to the sensor interface unit, and

a base unit interconnected with the sensor interface unit and wherein signals from the sensor interface unit are processed for display and recordation.

15. An integral optical fiber sensor probe comprising

three optical fibers for transmitting light, each optical fiber having a bend therein,

the fiber bends and a portion of the fibers adjacent the fiber bends encapsulated within cured potting encapsulant material forming a solid integral probe body which is generally cylindrical along its length and having a diameter across its length,

three sample chambers formed in the cured potting encapsulant material of the solid integral probe body, each sample chamber disposed in a gap formed in each of the three optical fibers and defined by side walls and a bottom wall and having an open portion,

each sample chamber disposed between two opposed fiber faces of optical fibers opposite each other on opposite sides of the sample chamber, light transmitted through one of the optical fibers passing through the sample chamber form one fiber face to the other,

each sample chamber containing a chemical indicating material covering the two opposed fiber faces, the chemical indicating material for changing in response to a specific chemical passing into the sample chamber through the open portion of the sample chamber so that light is changed which is transmitted from one opposed fiber face and through changed chemical indicating material to the other fiber face,

the generally cylindrical solid internal probe body having a diameter of 650 microns or less,

a selective membrane disposed over each open portion of each sample chamber, the membrane for selectively permitting the specific chemical to pass through the membrane to the chemical indicating material,

the sample chambers generally five-sided having length, width, and depth

the length ranging between 85 microns and 115 microns,

the width ranging between 130 microns and 160 microns and

the depth ranging between 130 microns and 160 microns,

the sample chambers spaced apart a longitudinal distance along the probe body ranging between 665 microns and 915 microns,

the solid integral probe body having a distal tip, and

a first sample chambers spaced apart a longitudinal distance along the probe body 2540 microns from the distal tip of the probe.

16. An integral optical fiber sensor probe comprising

a plurality of optical fibers for transmitting light, at least two of the optical fibers having a fiber bend therein,

the fiber bends and a portion of the fibers adjacent the fiber bends encapsulated within cured potting encapsulant material forming a solid integral probe body which is generally cylindrical along its length and having a diameter across its length ranging between 600 and 700 microns,

a plurality of sample chambers formed in the cured potting encapsulant material of the solid integral probe body, each sample chamber defined by side walls and a bottom wall and having an open portion,

each sample chamber disposed between two opposed fiber faces of the intersected optical fibers opposite each other on opposite sides of the sample chamber, one of said two opposed fiber faces being a face of one of the optical fibers having a fiber bend therein light transmitted through one of the optical fibers passing through the sample chamber from one fiber face to the other,

each sample chamber spaced apart by a longitudinal distance from the other chambers along the probe body of between 665 microns to 915 microns and containing a chemical indicating material covering the two opposed fiber faces, the chemical indicating material for changing in response to a specific chemical passing into the sample chamber through the open portion of the sample chamber so that light is changed which is transmitted from one opposed fiber face and through changed chemical indicating material to the other fiber face, and

the sample chambers generally five-sided having length, width, and depth,

the length ranging between 85 microns and 115 microns,

the width ranging between 130 microns and 160 microns and

the depth ranging between 130 microns and 160 microns.

17. The probe of claim 16 comprising also a selective membrane disposed over each open portion of each sample chamber, the membrane for selectively permitting the specific chemical to pass through the membrane to the chemical indicating material.

18. The probe of claim 16 wherein

the plurality of optical fibers is three optical fibers, and

the plurality of sample chambers is three sample chambers, one sample chamber formed to intersect each of the three optical fibers.

19. The probe of claim 18 wherein the sample chambers are spaced apart by a longitudinal distance along the probe body of 790 microns.

20. The probe of claim 16 wherein

the solid integral probe body has a distal tip, and a first sample chamber is spaced apart a longitudinal distance along the probe body from the distal tip ranging between 2240 microns and 2840 microns.

21. The probe of claim 20 wherein the first sample chamber is about 2540 microns from the distal tip of the probe.

22. The probe of claim 16 wherein the length of each of the sample chambers is 100 microns and the width of each of the sample chambers is 145 microns.

23. The probe of claim 16 wherein

the probe body is between 600 and 650 microns in diameter.

24. The probe of claim 16 wherein the portions of the fibers adjacent the fiber bends and the fiber bends are spaced apart from each other in the solid integral probe body.

25. The probe of claim 16 wherein there are three sample chambers, one related to each optical fiber, one sample chamber containing a pH indicator, one sample chamber containing an oxygen indicator, and one sample chamber containing a carbon dioxide indicator.

26. The probe of claim 16 including also a thermocouple with a metal bead in an end of the probe body and two metal leads extending from the end of the probe body with ends of the optical fibers.

27. The probe of claim 26 wherein the thermocouple is disposed more centrally in the probe than are the optical fibers.

28. The probe of claim 16 including also

a plastic connector secured to the probe for facilitating introduction of the probe into an intra-arterial cannula, the connector having a separate channel that permits fluids to be taken from or introduced into the cannula while the probe is in place within the cannula,

a tubing harness connected to the connector for protecting and containing a portion of the optical fibers of the probe,

a junction box to which the tubing harness extends and with which the tubing harness is interconnected,

a sensor interface unit for providing light input to the probe and for detecting and measuring light coming out of the probe, the optical fibers extending from the junction box to the sensor interface unit, and

a base unit interconnected with the sensor interface unit and wherein signals from the sensor interface unit are processed for display and recordation.