Integrated ultrasonic diagnosis device utilizing intra-blood-vessel probe

• US 5,125,410 A
• Filed: 08/22/1990
• Issued: 06/30/1992
• Est. Priority Date: 10/13/1989
• Status: Expired due to Term

• Current Assignee: Olympus Optical Corporation Limited (Olympus Corporation)
• Original Assignee: Olympus Optical Corporation Limited (Olympus Corporation)
• Inventors: Yamamoto, Katsuyuki, Misono, Kazuhiro, Fujimoto, Hiroshi
• Primary Examiner(s): Jaworski, Francis
• Assistant Examiner(s): MANUEL, GEORGE C
• Application Number:
  US07/570,764
• Time in Patent Office: 678 Days
• Field of Search: 128/662.06, 128/637, 128/692, 128/4-6, 128/660.03, 128/303.15, 128/908
• US Class Current: 600/463
• CPC Class Codes: A61B 8/06 Measuring blood flow measuring volume flow in general G01F, e.g. G01F1/66, G01F1/72; measuring speed of fluids in general G01P5/00
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/145 characterised by scanning multiple planes
• CPC Class Codes: A61B 8/445 Details of catheter construction
• CPC Class Codes: A61B 8/4461 Features of the scanning mechanism, e.g. for moving the transducer within the housing of the probe
• CPC Class Codes: A61B 8/463 characterised by displaying multiple images or images and diagnostic data on one display composite display in devices for short-range imaging with acoustic waves G01S7/52074
• CPC Class Codes: G10K 11/355 Arcuate movement
• CPC Class Codes: Y10S 128/908 Patient protection from electric shock

Abstract

An ultrasonic diagnosis device includes an ultrasonic oscillator, contained in a probe which can be inserted into a blood vessel, which can vary direction of transmission and reception of ultrasonic waves to receive an echo signal from the wall of the blood vessel thereby calculating information about the inner and outer walls of a blood vessel and obtaining cross-sectional and three-dimensional images of a blood vessel and the like.

Claims

1. An ultrasonic diagnosis device comprising:

an ultrasonic probe having an insertable portion insertable into a blood vessel and incorporating an ultrasonic oscillator for transmitting and receiving an ultrasonic wave, said ultrasonic probe having an internal power source;

a scanning means for rotatively and/or linearly scanning an emitting direction of said ultrasonic wave;

a reception signal outputting means for outputting a reception signal corresponding to an ultrasonic echo signal which has been received by said ultrasonic oscillator after transmission of the ultrasonic wave from said ultrasonic oscillator; and

a quantitative detecting means for determining, based upon said ultrasonic echo signal, at least one of a cross-sectional area of a blood vessel, a diameter of the blood vessel, a thickness of a blood vessel wall and pulsative changes thereof.

2. A device according to claim 1 further comprising a cross-sectional image generating means for generating a video signal corresponding to an acoustic cross-sectional image of the blood vessel from the reception signal from the reception signal output means and a monitor means displaying the acoustic cross-sectional image upon input of the video signal.

3. A device according to claim 2 wherein the cross-sectional image generating means comprises a scanning signal generating means having an input of an angle information corresponding to each direction in which the ultrasonic wave is transmitted from the ultrasonic oscillator and an input of time, which is a period after transmission of the ultrasonic wave in each direction, until detection of the ultrasonic echo signal by the ultrasonic oscillator, and said scanning signal generating means for generating a scanning signal which determined a position of display of the video signal to be displayed on the monitor means.

4. A device according to claim 2 wherein the ultrasonic probe comprises a photoelectrical element for transmitting signals with the cross-sectional image generating means over an optical fiber.

5. A device according to claim 2 further comprising an internal power source.

6. A device according to claim 1 wherein the ultrasonic probe comprises a pressure sensor for detecting pressure at the insertable portion.

7. A device according to claim 6 further comprising elasticity calculating means for calculating elasticity of the blood vessel from an output signal from the quantitative detecting means and an output signal from the pressure sensor.

8. A device according to claim 6 further comprising a pressure change quantity calculating means for calculating an amount of change in pressure inside the blood vessel wall from an output of the pressure sensor.

9. A device according to claim 1 and comprising a three-dimensional image generating mans for generating a three-dimensional image of the blood vessel wall from the reception signal.

10. A device according to claim 1 wherein the scanning means comprises a rotary drive means for driving the ultrasonic oscillator in rotary motion in an angular direction about a longitudinal axis of the ultrasonic probe wherein the emitting direction of transmission and a direction of reception of the ultrasonic wave is mechanically changed.

11. A device according to claim 10 wherein the rotary drive means comprises a motor.

12. A device according to claim 10 further comprising a translatory drive means for moving the ultrasonic oscillator in the axial direction to an ultrasonic probe.

13. A device according to claim 12 wherein the translatory drive means is a reciprocating drive means for reciprocating the ultrasonic oscillator in the axial direction.

14. A device according to claim 12 further comprising travel quantity detecting means for detecting an amount of travel of the ultrasonic oscillator in the axial direction.

15. A device according to claim 14 further displaying a three-dimensional image of the blood vessel from the reception signal depending on the amount of travel of the ultrasonic probe in the axial direction.

16. A device according to claim 1 wherein the ultrasonic oscillator comprises a plurality of ultrasonic oscillator elements arranged in an angular direction about a longitudinal axis of the ultrasonic probe and wherein the scanning means electronically changes the emitting direction of transmission and a direction of reception of the ultrasonic wave by selecting the ultrasonic element to be driven.

17. A device according to claim 10 or claim 3 further comprising angle detecting means for detecting the angular direction in which the ultrasonic wave is transmitted by the ultrasonic oscillator.

18. A device according to claim 17 wherein the quantitative detecting means comprises measuring means for measuring a period from transmission of the ultrasonic wave from the ultrasonic oscillator until reception of the ultrasonic echo signal received by the ultrasonic oscillator.

19. A device according to claim 18 wherein the quantitative detecting means comprises a cursor signal generating means for outputting a cursor to indicate a location at which the ultrasonic echo signal has been generated to a monitor means from the period measured by the measuring means and angle information detected by the angle detecting means.

20. A device according to claim 19 wherein the reception signal output means comprises gate means for eliminating the ultrasonic wave received within a certain period after transmission of the ultrasonic wave from the ultrasonic oscillator.

21. A device according to claim 20 wherein the gate means eliminates the ultrasonic echo signal reflected by a cap containing the ultrasonic oscillator.

22. A device according to claim 20 wherein the gate means eliminates the ultrasonic echo signal reflected by a balloon attached to an outside of a cap containing the ultrasonic oscillator.

23. A device according to claim 20 wherein the reception signal output means comprises determining means for determining whether a received ultrasonic echo signal exceeds a reference level.

24. A device according to claim 23 wherein the quantitative detecting means comprises a memory means for storing the period measured by the measuring means upon a first signal output through the gate means and the determining means.

25. A device according to claim 23 wherein the reception signal output means comprises a memory means for storing each period measured by the measuring means from output of first and second signals output through the gate means and the determining means.

26. A device according to claim 18 wherein the measuring means comprises a counter for counting a reference clock synchronized with a time in which the ultrasonic wave is transmitted by the ultrasonic oscillator.

27. A device according to claim 1 wherein the ultrasonic probe has a preamplifier for amplifying the ultrasonic echo signal received by the ultrasonic oscillator.

28. A device according to claim 1 wherein the quantitative detecting means outputs information about the blood vessel in real time.

29. A device according to claim 1 wherein the quantitative detecting means comprises measuring means for measuring a period after transmission of the ultrasonic wave by the ultrasonic oscillator until reception of the ultrasonic echo signal received by the ultrasonic oscillator, measurement of said period being carried out in said measuring means in plural directions about a longitudinal axis of the ultrasonic probe.

30. A device according to claim 29, wherein the quantitative detecting means comprises a distance calculating means which calculates at least either a distance up to an inner surface or an outer surface of the blood vessel wall from a position of ultrasonic wave transmission, based on the period measured by the measuring means.

31. A device according to claim 29 wherein the quantitative detecting means comprises a cross-sectional area calculating means which calculates a distance from a point of ultrasonic wave transmission to a boundary between a thrombus and blood, and to an inner surface of the wall of the blood vessel based on the period measured by the measuring means therein calculating a ratio of cross-sectional area of the thrombus to cross-sectional area of the blood vessel.

32. A device according to claim 1 further and comprising a thickness calculating means for calculating thickness of the blood vessel wall.

33. A device according to claim 32 wherein the thickness calculating means comprises an average thickness calculating means for calculating an average thickness of the blood vessel wall.

34. A device according to claim 1 wherein the quantitative detecting means comprises a cross-sectional area calculating means for calculating the cross-sectional area of the blood vessel wall.

35. A device according to claim 34 wherein the cross-sectional area calculating means comprises an average cross-sectional area calculating means for calculating an average cross-sectional area of the blood vessel wall.

36. A device according to claim 34 wherein the cross-sectional area calculating means comprises a cross-sectional area change quantity calculating means for calculating an amount of the change in a cross-sectional area of the blood vessel wall depending on time.

37. A device according to claim 1 wherein the ultrasonic probe comprises a support means at a head portion of the insertable portion for supporting a part of the insertable portion onto an inner wall of the blood vessel.

38. A device according to claim 37 wherein the support means is formed of an elastic member which may project and withdraw from an opening formed on the insertable portion.

39. A device according to claim 38 wherein the opening is a plurality of openings formed in a circumferential direction of a head portion side of the insertable portion and the elastic member is a flexible wire which may project and withdraw from each opening.

40. A device according to claim 39 wherein the flexible wire may project and withdrawn from each opening at one of the ends thereof and may be controlled based on an amount of projection from the opening by operating another end thereof which penetrates through the probe up to a base of the probe.

41. A device according to claim 38 wherein the elastic member may be controlled based on an amount of projection from the opening by operation at a probe base side.

42. A device according to claim 37 wherein the support means is a balloon which is attached to an outer circumference of the insertable portion.

43. A device according to claim 1 wherein the ultrasonic probe is provided at a head portion of the insertable portion and is contained in a cap having an acoustic window which transmits at least ultrasonic waves.

44. A device according to claim 43 wherein the acoustic window is covered by a ultrasonic transparent member which transmits ultrasonic waves.

45. A device according to claim 43 wherein within the cap, ultrasonic transmitting liquid surrounds the ultrasonic oscillator.

46. A device according to claim 1 wherein the reception signal output means comprises voltage variable amplifying means or a voltage variable band-pass filter which are voltage-controlled with regard to gain or passing band against the ultrasonic echo signal received by the ultrasonic oscillator.

47. A device according to claim 46 further comprising a control signal generating means for varying a level of voltage which controlls voltage variable amplifying means or voltage variable band-pass filter, when a reference time has elapsed after the transmission of the ultrasonic wave by the ultrasonic oscillator.

48. A device according to claim 47 further comprising a reference time changing means for changing the reference time.

49. A device according to claim 48 wherein the reference time is variably set by probe information corresponding to the ultrasonic probe which is being used.

50. A device according to claim 49 further comprising a light pen which variably sets the reference time.

51. A device according to claim 1 wherein the ultrasonic probe comprises a driving circuit for driving the ultrasonic oscillator which operates on power supplied by the internal power source.

52. A device according to claim 1 wherein the quantitative detecting means calculates an average value of the information about the blood vessel in a period of pulsant change of the blood vessel.

53. A device according to claim 1 wherein the scanning means comprises a rotary driving means for driving the ultrasonic oscillator in a rotary motion and a shaft member which penetrates through the insertable portion, the shaft member is attached to an input portion of the ultrasonic oscillator on one end of the shaft member and connected to the rotary driving means on another end of the shaft member.

54. A device according to claim 1 wherein the ultrasonic oscillator comprises a plurality of oscillator elements for transmitting and receiving said ultrasonic echo signal of the ultrasonic wave, said oscillator elements are attached to a head portion side of the insertable portion in a circumferential direction to the insertable portion.