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Dosage form for Parkinson's disease, spasticity and muscle spasms

  • US 5,128,145 A
  • Filed: 08/02/1991
  • Issued: 07/07/1992
  • Est. Priority Date: 06/13/1990
  • Status: Expired due to Term
First Claim
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1. A dosage form for delivering a drug to a drug receptor, wherein the dosage form comprises:

  • (a) a wall comprising at least in part a composition permeable to the passage of fluid, which wall surrounds;

    (b) a compartment;

    (c) at least one exit port in the wall that connects the exterior of the dosage form with the compartment;

    (d) a dispensing composition in the compartment comprising a maltodextrin comprising a 500 to 1,000,000 molecular weight and a degree of polymerization of 3 to 6,140;

    (e) 1 mg to 750 mg of drug in the dispensing composition for delivering the drug, by the combined operations of (a) and (b), through the exit port from the dosage form; and

    ,(f) a push composition in the compartment comprising a hydrogel and an osmotically effective solute, which composition in the presence of fluid that enters the compartment increases in volume and thereby pushes the dispensing composition from the dosage form.

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