Blood plasma collection system

• US 5,132,026 A
• Filed: 03/21/1991
• Issued: 07/21/1992
• Est. Priority Date: 03/21/1991
• Status: Expired due to Term

• Current Assignee: Alpha Therapeutic Corporation (Grifols SA /Grifols Family/)
• Original Assignee: Alpha Therapeutic Corporation (Grifols SA /Grifols Family/)
• Inventors: Betancourt, Jesus, Hajduk, Patricia M., Baluyot, Rodolfo C., Dimmick, David M.
• Primary Examiner(s): Jones, W. Gary
• Application Number:
  US07/675,088
• Time in Patent Office: 488 Days
• Field of Search: 210/782, 210/789, 210/85, 210/257.1, 210/767, 210/516, 422/102, 436/177, 604/403, 604/404, 604/405, 604/409, 220/23.83, 220/23.4
• US Class Current: 210/767
• CPC Class Codes: A61J 1/05 for collecting, storing or administering blood, plasma or medical fluids multiple bags systems for separating or storing blood components A61M1/0209; Infusion or perfusion containers
• CPC Class Codes: A61J 1/12 with means for holding samples of contents
• CPC Class Codes: A61J 1/1412 Containers with closing means, e.g. caps
• CPC Class Codes: A61J 1/1418 Threaded type
• CPC Class Codes: A61J 1/145 using air filters
• CPC Class Codes: A61J 1/1468 Containers characterised by specific material properties
• CPC Class Codes: A61J 1/1487 with friction fit, e.g. connecting tubes directly to a protruding port
• CPC Class Codes: A61J 2205/10 Bar codes
• CPC Class Codes: A61J 2205/30 Printed labels
• CPC Class Codes: Y10T 436/25375 Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

Abstract

A blood plasma collection system comprises a sealed collection bottle with a flexible plastic transfer tube sealed into its top for collecting plasma. A flexible sample tube is also sealed into the top of the bottle and connects to a sample vial for receiving a plasma sample decanted from the bottle. The sample vial is sealed to the sample tube by a resilient plug. A vent tube and filter are also be connected to the plug. This permits a representative plasma sample to be decanted from the bottle into the sample vial after plasma is collected.

Claims

1. A blood plasma collection system comprising:

a sealed plasma collection bottle;

a flexible transfer tube connected to the top of the bottle for collecting plasma;

a flexible sample tube connected to the top of the bottle;

a removable sample vial connected to the sample tube for receiving a plasma sample decanted from the bottle; and

a vent connected to the sample vial.

2. A plasma collection system as recited in claim 1 further comprising indicia on the collection bottle and indicia on the sample vial for correlating the sample in the vial with the contents of the bottle.

3. A plasma collection system as recited in claim 1 wherein the sample vial comprises:

a rigid test tube;

a resilient plug in the test tube, the plug comprising means for maintaining a seal to the test tube; and

a pair of passages through the plug, the sample tube being sealed through one of the passages, and the vent being sealed to the other passage.

4. A plasma collection system as recited in claim 3 wherein the vent comprises a flexible tube connected to the passage and an air filter fine enough to prevent passage of microorganisms.

5. A plasma collection system as recited in claim 1 wherein the flexible tubes are each made of heat sealable material.

6. A plasma collection system as recited in claim 1 wherein the transfer tube comprises a Y having a leg connected to the bottle and an arm connected to the other end of the transfer tube and a second transfer tube connected to the other arm of the Y for collecting more than one plasma donation.

7. A blood plasma collection system comprising:

a sealed plasma collection bottle, the walls of the bottle being at least slightly flexible;

at least one heat sealable, flexible medical grade plastic transfer tube connected to the top of the bottle for collecting plasma;

a heat sealable, flexible medical grade plastic sample tube connected to the top of the bottle;

a resilient plug sealed on the end of the sample tube;

a rigid sample vial frictionally engaged on the plug for receiving a plasma sample decanted from the bottle through the sample tube;

a heat sealable, flexible medical grade plastic vent tube sealed to the plug for venting air from the vial; and

an air filter in the vent tube fine enough to prevent passage of microorganisms into the vial.

8. A plasma collection system as recited in claim 7 wherein the transfer tube comprises a Y having a leg connected to the bottle and an arm connected to the other end of the transfer tube and a second transfer tube connected to the other arm of the Y for collecting more than one plasma donation.

9. A plasma collection system as recited in claim 7 further comprising:

first indicia on the collection bottle for identifying plasma in the collection bottle; and

identical indicia on the sample vial for correlating the sample vial with the collection bottle.

10. A method for sampling collected blood plasma comprising the steps of:

collecting plasma in a sealed collection bottle;

decanting a portion of the plasma from the collection bottle into a sample vial sealed to the collection bottle by a flexible tube; and

heat sealing and severing the sample tube for sealing both the bottle and the vial and separating the vial from the bottle.

11. A method as recited in claim 10 further comprising venting air from the vial during the decanting.