Apparatus for rezeroing an in vivo pressure sensor and method for rezeroing

• US 5,133,358 A
• Filed: 09/07/1990
• Issued: 07/28/1992
• Est. Priority Date: 09/07/1990
• Status: Expired due to Fees

• Current Assignee: Becton, Dickinson & Co
• Original Assignee: Becton, Dickinson & Co
• Inventors: Erskine, Timothy J., Gustafson, Gary E., Richardson, Kim L., Ring, Wallace H., Kimble, Steven C.
• Primary Examiner(s): Grieb, William H.
• Assistant Examiner(s): Passaniti, Sebastiano
• Application Number:
  US07/578,712
• Time in Patent Office: 690 Days
• Field of Search: 128/673, 128/674, 128/675, 128/748, 73/4 R, 73/708
• US Class Current: 600/488
• CPC Class Codes: A61B 5/02156 Calibration means
• CPC Class Codes: G01L 27/005 Apparatus for calibrating pressure sensors

Abstract

A sensor assembly for an in vivo physiological pressure measurement has a member with a distal end to ease placement of the catheter sensor assembly in vivo. A passage is preferably in an intermediate part of the member and is open but covered by a pressure responsive sensor sealing the passage. The sensor has a first side away from the intermediate part for exposure to in vivo physiological pressure and a second side in fluid communication with the passage. A pressure connecting means for inhibiting liquid communication located between the physiological pressure and the passage is arranged for selectively connection therebetween so that when connected the pressure on the first and second sides of the sensor can be substantially equalized. A control ex vivo makes the selective connection of the second side of the pressure sensor and the physiological pressure. A method for rezeroing an in vivo pressure sensor has the steps of obtaining a signal from the first side of the sensor at distal end, using a pressure substantially equal to the in vivo pressure and applying that pressure to the second side of the sensor.

Claims

1. A catheter sensor assembly for rezeroing a physiological pressure sensor during measurement of in vivo physiological pressure comprising:

a) a member comprising a distal end to ease placement of the catheter sensor assembly in an in vivo site, an intermediate part and a proximal end for fluid connection of the member with a tube having a lumen which extends from the proximal end;

b) a passage in the intermediate part opened in a first direction, the passage extending through the proximal end and across the intermediate part;

c) a pressure responsive sensor carried upon said member for covering and sealing the passage, the sensor having a first side facing the first direction away from the intermediate part for exposure to in vivo physiological pressure, the sensor having a second side opposite the first side, the second side in fluid communication with the passage and the lumen; and

d) a pressure connecting means connected to the lumen for inhibiting liquid communication with the lumen and arranged for selective communication with a catheter in fluid communication with the first side to transmit the physiological pressure through the pressure connecting means, a circuitous path in the pressure connecting means for inhibiting liquid communication to isolate the first and the second sides of the sensor from liquid communication so that the pressure on the first and second sides of the sensor can be substantially equalized while inhibiting liquid communication during determination of a datum value of a signal from the sensor of the equalized pressure of the in vivo sensor.

2. The assembly of claim 1 wherein a control is positioned ex vivo and associated with the catheter, the control has a portion to operatively connect the pressure connecting means for inhibiting liquid communication so that the selective communication of the second side of the pressure sensor and the physiological pressure can be made by the portion.

3. The assembly of claim 2 wherein the control is a multi position valve associated with the pressure connecting means for inhibiting liquid communication to connect the circuitous path in series with the catheter and the lumen.

4. The assembly of claim 1 wherein the sensor is a semiconductor chip sealed to the member and responsive to a pressure differential between the in vivo physiological pressure on the first side and the pressure in the passage, when both sides receive substantially the same pressure, the time average datum value being equal to the zero offset of the pressure sensing device.

5. The assembly of claim 3 wherein the operation of the valve provides pressure communication through the pressure connecting means for inhibiting liquid communication between the lumen and the catheter in a first position to balance the fluid pressure on the first and second sides of the pressure sensing device and closes the lumen connection through the pressure connecting means for inhibiting liquid communication by opening the catheter in a second position.

6. The assembly of claim 4 wherein a circuit is connected to the pressure sensing device for adjusting the signal values of the pressure differential to account for the datum value so that corrected readings of the in vivo physiological pressure can be made.

7. The assembly of claim 6 wherein the pressure sensing device has a Wheatstone bridge circuit to provide a signal responsive to the pressure differential thereacross.

8. The assembly of claim 7 wherein the tube passes through the catheter to a connector for the catheter and the tube.

9. The assembly of claim 8 wherein the multiposition valve includes a housing to movably carry the portion, a first channel for the catheter and a second channel for the lumen.

10. The assembly of claim 9 wherein the circuitous path is arranged to be removably connected to the first and the second channels and wherein the second channel connects to the lumen before the first channel connects to the catheter.

11. A catheter sensor assembly for rezeroing a physiological pressure sensor during measurement of in vivo physiological pressure comprising:

a) a member comprising a distal end to ease insertion of the catheter sensor assembly in an in vivo site and a proximal end for fluid connection of the member with a lumen of a tube, the distal end and the proximal end joined by an intermediate part;

b) a passage in the intermediate part opened in a first direction and extending through the proximal end and across the intermediate part;

c) a sensor carried upon and overlying the passage, the sensor having a first side facing the first direction away from the intermediate part for exposure to in vivo pressure, the sensor having a second side opposite the first side wherein the second side is in fluid communication with the passage and the lumen;

d) a circuitous path arranged for selective connection to a catheter to provide pressure communication between the first and second sides and fashioned to prohibit flow of liquid but permit concurrent application of in vivo physiological pressure to the first and second sides; and

e) a control having a portion for selective operation to connect or disconnect the catheter and the tube to the circuitous path and located between the catheter and the circuitous path, the control being ex vivo so that the in vivo pressure can be remotely applied to the first and second sides of the sensor during determination of a datum value of pressure when the sensor remains in vivo.

12. The assembly of claim 11 wherein the determination is set when the circuitous path is at an elevation substantially equal to the elevation of the in vivo sensor.

13. The assembly of claim 12 wherein the circuitous path is removable and said assembly further comprising a pair of fittings, each of said fittings having a needle and a septum to receive a needle wherein one of said fittings is located where the circuitous path joins with the catheter and the other of said fittings is located where said circuitous path joins with the tube.

14. The assembly of claim 13 wherein the control includes a multiposition valve for selectively connecting the catheter either with the circuitous path or atmospheric pressure so that the circuitous path may be selectively interposed between the catheter and the tube to permit communication of in vivo pressure to the first and second sides of the sensor while inhibiting communication of fluid between the catheter and the tube.

15. The assembly of claim 14 wherein the multiposition valve is connected to a vent to the atmosphere and the tube and catheter are carried by a connector having a port connected to the tube.

16. A method for rezeroing an in vivo pressure sensor comprising the steps of:

a) obtaining a signal from an in vivo side of a sensor at the distal end of a lumen of an in vivo tube, the sensor having a first side exposed to a physiological pressure;

b) transmitting a pressure substantially equal to the physiological pressure through a catheter to the sensor and through a circuitous path;

c) applying the pressure in the circuitous path to the lumen to equalize the pressure on a second side of the sensor opposite to the first side; and

determining the signal with balanced pressure applied to the first and second sides of the in vivo sensor for use in correcting for zero offset.

17. The method of claim 16 wherein the step of selecting the pressure includes the step of removably and selectively connecting the lumen to the circuitous path or to atmospheric pressure.

18. The method of claim 17 wherein the step of selectively connecting includes the additional step of inhibiting fluid communication between the catheter and the tube.

19. The method of claim 18 wherein the step of selectively connecting has the added step of controlling the connection ex vivo.

20. The method of claim 19 wherein the step of controlling the connection is performed by operating a multiposition valve.