Implantable myocardial ischemia monitor and related method

• US 5,135,004 A
• Filed: 03/12/1991
• Issued: 08/04/1992
• Est. Priority Date: 03/12/1991
• Status: Expired due to Term

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: InControl, Inc. (Daikin Industries Ltd)
• Inventors: Alferness, Clifton A., Adams, John M.
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): SCHAETZLE, KENNEDY
• Application Number:
  US07/667,819
• Time in Patent Office: 511 Days
• Field of Search: 128/696, 128/702, 128/704, 128/705, 128/419 PG, 128/419 D
• US Class Current: 600/508
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/6852 Catheters

Abstract

An implantable device assists in the diagnosis of myocardial ischemia of a human heart and includes a plurality of electrodes and a like plurality of sense amplifiers for generating an electrogram for each of the electrodes. A digital to analog converter reads the voltage magnitudes of the electrogram ST segments which are then stored in a memory. An implantable receiver/transmitter is arranged to transmit the magnitudes of the electrogram ST segments to a nonimplanted external receiver.

Claims

1. An apparatus for assisting in the diagnosis of myocardial ischemia of a human heart, said apparatus being fully implantable beneath the skin of a patient and comprising:

at least one electrode, said electrode being implantable beneath the skin of a patient and arranged for establishing electrical contact with the heart;

sensing means implantable beneath the skin of a patient, said sensing means being coupled to said at least one electrode for generating an electrogram representative of the activity of the heart at said at least one electrode, said electrogram including ST segments having voltage magnitudes;

read means implantable beneath the skin of a patient for reading the voltage magnitudes of said electrogram ST segments;

memory means implantable beneath the skin of a patient and coupled to said read means for storing the voltage magnitudes of said electrogram ST segments; and

communication means implantable beneath the skin of a patient and coupled to said memory means for transmitting said magnitudes of said electrogram ST segments to a nonimplanted external receiver.

2. An apparatus as defined in claim 1 including a plurality of said electrodes and wherein said sensing means is arranged to generate an electrogram for each said electrode.

3. An apparatus as defined in claim 2 wherein said electrodes are arranged to be attached to the human heart.

4. An apparatus as defined in claim 1 wherein said read means comprises an analog to digital converter.

5. An apparatus as defined in claim 2 wherein said sensing means comprises a plurality of sense amplifiers, each said sense amplifier being coupled to a respective one of said electrodes.

6. An apparatus as defined in claim 5 further including a multiplexer having a plurality of inputs coupled to said sense amplifiers and an output coupled to said read means for coupling each of said sense amplifiers to said read means one at a time.

7. An apparatus as defined in claim 6 wherein said read means comprises an analog to digital converter.

8. An apparatus as defined in claim 1 wherein said sensing means, said read means, said memory means, and said communication means are enclosed within a common enclosure.

9. An apparatus as defined in claim 2 wherein said electrodes are unipolar electrodes.

10. An apparatus as defined in claim 1 further including a microprocessor coupled between said read means and said memory means for controlling the reading of said electrogram ST segment voltages and the storing of said ST segment voltage magnitudes in said memory means.

11. An apparatus as defined in claim 10 wherein said microprocessor is coupled between said memory means and said communication means.

12. An apparatus as defined in claim 11 wherein said communication means is arranged for receiving commands from an external source.

13. An apparatus as defined in claim 12 wherein said microprocessor is arranged to determine the difference between said sensed ST segment voltages and a base line voltage and to activate said alarm means when the absolute magnitude of at least one of said differences exceeds a commanded limit.

14. An apparatus as defined in claim 13 wherein said microprocessor is arranged to determine the difference between said sensed ST segment voltage and said base line voltage and to cause an ST segment voltage magnitude to be stored in said memory means only when the absolute magnitude of its corresponding difference exceeds a commanded limit.

15. An apparatus as defined in claim 14 wherein said microprocessor is further arranged to provide a time stamp for each ST segment voltage magnitude entered into said memory means.

16. A method of providing data for use in diagnosing myocardial ischemia of a human heart, said method including the steps of:

providing at least one electrode;

implanting said electrode beneath the skin of a patient;

establishing electrical contact between said electrode and the heart of the patient;

providing sensing means implanted beneath the skin of the patient coupled to said electrode;

generating an electrogram for said electrode representative of the activity of the heart at said electrode, said electrogram including ST segments;

providing voltage read means implanted beneath the skin of the patient;

reading the voltage magnitudes of said electrogram ST segments;

providing memory means implanted beneath the skin of the patient coupled to said voltage read means;

storing the voltage magnitudes of said electrogram ST segments in said memory means;

providing communication means implanted beneath the skin of the patient coupled to said memory means; and

transmitting said magnitudes of said electrogram ST segments to a nonimplanted external receiver.

17. A method as defined in claim 16 wherein said electrode is an epicardial electrode.

18. A method as defined in claim 16 wherein said sensing means is formed of at least one sense amplifier, said at least one sense amplifier being coupled to said at least one electrode.

19. A method as defined in claim 18 further including the step of converting said ST segment voltages from analog form to digital form.

20. A method as defined in claim 19 further including the step of synchronizing the reading of said electrogram ST segment voltages and the storing of said ST segment voltage magnitudes in said memory means.

21. A method as defined in claim 16 including the further steps of determining the difference between said sensed ST segment voltages and a base line voltage and providing an alarm when the absolute magnitude of at least one of said differences exceeds a predetermined limit.

22. A method as defined in claim 16 including the further steps of determining the difference between each sensed ST segment voltage and a base line voltage and storing a sensed ST segment voltage magnitude in said memory only when the absolute magnitude of its corresponding difference exceeds a predetermined limit.

23. A method as defined in claim 22 including the further step of time stamping each stored ST segment voltage entry.

24. A method of providing data for use in diagnosing myocardial ischemia of a human heart, said method including the steps of:

providing a plurality of electrodes;

implanting said electrodes beneath the skin of a patient;

establishing electrical contact between said electrodes and respective different regions of the heart of the patient;

providing sensing means implanted beneath the skin of the patient coupled to said electrodes;

generating an electrogram for each said electrode representative of the activity of the heart at each said electrode, each said electrogram including ST segments;

providing voltage read means implanted beneath the skin of the patient;

reading the voltage magnitudes of said ST segments of each of said electrograms;

providing memory means implanted beneath the skin of the patient coupled to said voltage read means;

storing the voltage magnitudes of said ST segments of each said electrogram in said memory means;

providing communication means implanted beneath the skin of the patient coupled to said memory means; and

transmitting said magnitudes of said electrogram ST segments to a nonimplanted external receiver.

25. A method as defined in claim 24 wherein said electrodes are epicardial electrodes.

26. A method as defined in claim 24 wherein said sensing means is formed of a plurality of sense amplifiers, each said sense amplifier being coupled to a respective one of said electrodes.

27. A method as defined in claim 24 further including the step of converting said ST segment voltages from analog form to digital form.

28. A method as defined in claim 24 further including the step of synchronizing the reading of said electrogram ST segment voltages and the storing of said ST segment voltage magnitudes in said memory means.

29. A method as defined in claim 24 including the further steps of determining the difference between said sensed ST segment voltages and a base line voltage and providing an alarm when the absolute magnitude of at least one of said differences exceeds a predetermined limit.

30. A method as defined in claim 24 including the further steps of determining the difference between each sensed ST segment voltage and a base line voltage and storing a sensed ST segment voltage magnitude in said memory only when the absolute magnitude of its corresponding difference exceeds a predetermined limit.

31. A method as defined in claim 30 including the further step of time stamping each stored ST segment voltage entry.