Method of imaging a random medium
First Claim
1. A method for imaging a three-dimensional target object or other optical inhomogeneity in a turbid medium, comprising the steps of:
- providing a substantially collimated beam of radiation and directing the beam onto a surface of a turbid medium containing a target object;
providing a substantially collimated receiver to receive scattered radiation;
performing positional scans comprising source-detector configurations having different source detector, separations and angles of the scattered radiation over the surface of the turbid medium at various separations and angles;
applying the data obtained from each positional scan to form a three-dimensional image of the target object by;
a. determining attenuation of emerging radiation from said target medium relative to a model medium;
b. determining a relative contribution of volume elements for each source-detector configuration;
c. superimposing the relative contribution of volume elements for all source-detector configurations;
d. obtaining a spectroscopic image;
e. displaying said spectroscopic image.
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Accused Products
Abstract
A non-invasive medical imaging technique capable of evaluating, in situ, the oxygenation state of body tissues (e.g., by measuring the spectral properties of heme proteins) is described. The technique is based on the measurement of scattered radiation in the near-infrared region (NIR), where significant penetration into body tissues occurs. The disclosed technique employs a multi-wavelength collimated source and a collimated receiver and performs a positional and angular scan of the scattered radiation for each position of the incident beam. The resultant data is evaluated by employing imaging schemes which give differential weights to the contribution of various volume elements (voxels) in the medium to the detector response. A three-dimensional spectroscopic image of the target medium is determined by considering the contribution of the various volume elements for each source-detector configuration and position of the incident beam at various frequencies. These measurements, in an imaging mode, yield vital physiological information while being, for example, a sensitive indicator of subtle physiological stress caused by disease or trauma.
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Citations
23 Claims
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1. A method for imaging a three-dimensional target object or other optical inhomogeneity in a turbid medium, comprising the steps of:
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providing a substantially collimated beam of radiation and directing the beam onto a surface of a turbid medium containing a target object; providing a substantially collimated receiver to receive scattered radiation; performing positional scans comprising source-detector configurations having different source detector, separations and angles of the scattered radiation over the surface of the turbid medium at various separations and angles; applying the data obtained from each positional scan to form a three-dimensional image of the target object by; a. determining attenuation of emerging radiation from said target medium relative to a model medium; b. determining a relative contribution of volume elements for each source-detector configuration; c. superimposing the relative contribution of volume elements for all source-detector configurations; d. obtaining a spectroscopic image; e. displaying said spectroscopic image. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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Specification