System and method for oxygenation of the heart using subpericardial fluids
First Claim
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1. A system for oxygenation of the heart, comprisinga guiding catheter;
- a solution delivery catheter; and
means for supplying preoxygenated carrier solution through said delivery catheter;
wherein said guiding catheter provides means to guide said delivery catheter into the pericardial space between the pericardium and the epicardial surface of the heart;
wherein said delivery catheter is constructed so it may be threaded through said guiding catheter and includes means to contact the interior of the pericardial space;
wherein said means for supplying preoxygenated carrier solution comprises means for administering said carrier solution through said delivery catheter directly into the pericardial space, withdrawing said carrier solution from the pericardial space, and replenishing said carrier solution to the pericardial space.
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Abstract
The present invention relates to a system and method for oxygenation of ischemic tissue. In particular, the present invention relates to a system and method for supplying oxygen to the myocardium of the heart through means other than the coronary arteries. The system of the present invention comprises a catheter which may be used to infuse preoxygenated carrier solutions, such as perfluorocarbon emulsions, directly into the pericardial space; i.e. the space between the pericardium and the epicardial surface. The preoxygenated solutions may be periodically or continuously withdrawn and fresh solutions then infused into the pericardial space.
37 Citations
39 Claims
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1. A system for oxygenation of the heart, comprising
a guiding catheter; -
a solution delivery catheter; and means for supplying preoxygenated carrier solution through said delivery catheter; wherein said guiding catheter provides means to guide said delivery catheter into the pericardial space between the pericardium and the epicardial surface of the heart; wherein said delivery catheter is constructed so it may be threaded through said guiding catheter and includes means to contact the interior of the pericardial space; wherein said means for supplying preoxygenated carrier solution comprises means for administering said carrier solution through said delivery catheter directly into the pericardial space, withdrawing said carrier solution from the pericardial space, and replenishing said carrier solution to the pericardial space. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A system for oxygenation of body tissue, comprising
a guiding catheter; -
a solution delivery catheter; and means for supplying preoxygenated carrier solution through said delivery catheter; wherein said guiding catheter provides means to guide said delivery catheter into a space between a covering membrane of the tissue and the surface of the tissue; wherein said delivery catheter is constructed so it may be threaded through said guiding catheter and includes means to contact the interior of said space; wherein said means for supplying preoxygenated carrier solution comprises means for administering said carrier solution through said delivery catheter directly into said space, withdrawing said carrier solution from said space, and replenishing said carrier solution to said space. - View Dependent Claims (19)
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20. A method of delivering a preoxygenated carrier solution to the heart of a patient, said method comprising;
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inserting a guiding catheter through the vasculature of the patient until said guiding catheter is in contact with the pericardium; providing a slight vacuum through said guiding catheter so as to separate the pericardium from the heart thereby forming a pericardial space between the pericardium and the epicardial surface of the heart; puncturing the pericardium; threading a delivery catheter through said guiding catheter until said delivery catheter is in contact with the interior of the pericardial space; delivering said carrier solution through said delivery catheter and into the pericardial space; and withdrawing carrier solution from and replenishing carrier solution to the pericardial space. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37)
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38. A method of oxygenating body tissue of a patient, said method comprising;
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inserting a guiding catheter through the vasculature of the patient until said guiding catheter is in contact with a membrane surrounding said body tissue; providing a slight vacuum through said guiding catheter so as to separate the membrane from the tissue surface thereby forming a space between the membrane and the tissue surface; puncturing the membrane; threading a delivery catheter through said guiding catheter until said delivery catheter is in contact with the interior of said space; delivering said carrier solution through said delivery catheter and into said space; and
withdrawing carrier solution from and replenishing carrier solution to said space. - View Dependent Claims (39)
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Specification