Triggered application device for medicament to be more descriptive of the invention

• US 5,137,516 A
• Filed: 11/27/1990
• Issued: 08/11/1992
• Est. Priority Date: 11/28/1989
• Status: Expired due to Term

• Current Assignee: Glaxo Group Limited (Glaxosmithkline Holdings Ltd.)
• Original Assignee: Glaxo Group Limited (Glaxosmithkline Holdings Ltd.)
• Inventors: Regan, Philip M., Rand, Paul K.
• Primary Examiner(s): Hirsch, Paul J.
• Application Number:
  US07/618,746
• Time in Patent Office: 623 Days
• Field of Search: 604/130, 604/134, 604/137, 604/136
• US Class Current: 604/136
• CPC Class Codes: A61J 1/00 Containers specially adapted for medical or pharmaceutical purposes capsules or the like for oral use A61J3/07; specially adapted for surgical or diagnostic appliances or instruments A61B50/30; containers for radioactive substances G21F5/00
• CPC Class Codes: A61M 2005/202 cocking means, e.g. to bias the main drive spring of an injector
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2005/208 Release is possible only when device is pushed against the skin, e.g. using a trigger which is blocked or inactive when the device is not pushed against the skin
• CPC Class Codes: A61M 2005/3109 Caps sealing the needle bore by use of, e.g. air-hardening adhesive, elastomer or epoxy resin
• CPC Class Codes: A61M 2005/3142 Modular constructions, e.g. supplied in separate pieces to be assembled by end-user
• CPC Class Codes: A61M 5/002 Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics needle protection, e.g. caps, A61M5/3202; for sharps A61B50/3001
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/28 Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
• CPC Class Codes: A61M 5/3202 Devices for protection of the needle before use, e.g. caps A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001
• CPC Class Codes: A61M 5/3204 Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
• CPC Class Codes: A61M 5/326 Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
• CPC Class Codes: A61M 5/46 having means for controlling depth of insertion
• CPC Class Codes: A61M 5/5086 for indicating if defective, used, tampered with or unsterile

Abstract

The application describes an administering device, in particular a self-injecting device, comprising a body for holding a container of a substance to be administered, a release mechanism, and means controlled by the release mechanism to discharge the said substance. The body is formed of two parts, one part being movable relative to the other, wherein one part has a trigger and the said release mechanism is partly actuated by the operation of a trigger of the said one part and partly actuated by movement of the other part relative to the said one part, but is only wholly actuated by both the operation of the trigger and the movement of the other part. Thus the discharge means cannot be accidentally actuated.

Claims

1. An administering device comprising:

a body for holding a container of substance to be administered, a release mechanism, means controlled by the release mechanism to discharge the said substance, and a trigger, the release mechanism being capable of releasing the discharge means by cooperating with the trigger;

wherein the body is formed of two parts, a first part and a second part, the two parts being movable relative to one another along a predetermined axis between a first and a second position;

wherein the trigger is mounted on the first part and the release mechanism is is mounted on the second part;

whereby the trigger is movable substantially along said predetermined axis between the first position and the second position in a direction towards the release mechanism;

wherein, in the second position, the release mechanism is nearer to the trigger than in the first position; and

wherein only in the second position is the trigger capable of cooperating with the release mechanism to release the discharge means, whereby the discharge means cannot be accidentally released.

2. An administering device according to claim 1, wherein said second part is slidably mounted within said first part and extends out of said first part.

3. An administering device according to claim 2, wherein the release mechanism is mounted at an end of the second part, the trigger of the first part being in the form of a push button towards which the release mechanism is moved by movement of the second part with the first part.

4. An administering device according to claim 3, wherein the container is a syringe held within the said second part and wherein actuation of the discharge means firstly moves the syringe forward within the second part to expose the needle, and thus to urge it through the skin, and secondly depresses the plunger of the syringe to administer the substance to the user.

5. An administering device according to claim 4, wherein the discharge means is an elongate pusher rod which is urged by means of a resilient force and wherein the release mechanism comprises a pair of arms over which the end of the pusher rod is held, the rod being released by relative movement of the button to separate the arms.

6. An administering device according to claim 5, wherein the one part of the device which moves within the other is itself comprised of two parts, a first part extending out of the device and being in the form of a sleeve which houses the syringe and a second part within the device which houses the pusher rod, the first and second parts of the one part being releasably connectable together.

7. An administering device according to claim 6, wherein the said sleeve comprises an inner and an outer sleeve part, the sleeve parts being movable relative to each other against the action of a spring.

8. An administering device according to claim 1, wherein the administering device is elongate and generally cylindrical and thus is similar to a pen in shape.

9. An administering device according to claim 1, wherein the said substance is a pharmaceutical substance useful in treating migraine and related disorders such as cluster headache.

10. An administering device according to claim 9, wherein the pharmaceutical substance is sumatriptan.

11. A combination of an administering device according to claim 1 and a housing for at least one container of the substance to be discharged, the housing comprising a removable sleeve for the container and means releasably holding the sleeve within the housing, the said sleeve having means to releasably attach itself to the first part of the administering device, whereby the sleeve and container can be removed from the housing by co-operation with the administering device and can be returned to the housing after use.

12. A combination according to claim 11, wherein the housing has a lid which is closed after the used container is returned thereto.

13. A combination according to claim 11, wherein the container is a syringe having a rubber cap protecting the needle, this cap remaining within the housing when the sleeve is removed by the administering device.

14. A combination according to claim 13, wherein the syringe is held within the sleeve against the action of a spring.

15. A combination according to claim 11, together with a casing for the combination, the casing having a recess for the administering device, the recess including means to prime the release mechanism when the device is placed into the recess.

16. An administering device according to claim 1, wherein the container is moveable within the body against the discharge means and wherein the device further comprises means to prevent discharge of the substance until the discharge means is engaged by the release mechanism, whereby the loading of the container into the body can simultaneously engage the discharge means with the release mechanism.

17. An administering device according to claim 16, wherein the container is a syringe and a rubber cap is provided over the syringe needle to seal the syringe so that the syringe itself can be used to move the discharge means.