Apparatus for measuring biopermeability

• US 5,144,951 A
• Filed: 01/27/1992
• Issued: 09/08/1992
• Est. Priority Date: 03/09/1989
• Status: Expired due to Fees

• Current Assignee: Kazuo Tsuji, Macttor Company Limited, Shigehiro Kinoshita
• Original Assignee: Kazuo Tsuji, Macttor Company Limited, Shigehiro Kinoshita
• Inventors: Kinoshita, Shigehiro, Tsuji, Kazuo, Uematsu, Kazuma
• Primary Examiner(s): Smith, Ruth S.
• Assistant Examiner(s): Nusser, R. L.
• Application Number:
  US07/825,323
• Time in Patent Office: 225 Days
• Field of Search: 128/633, 128/664-666, 356/41
• US Class Current: 600/476
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters

Abstract

An apparatus for measuring biopermeability is disclosed. The apparatus includes a frame, a light source, a light-receiving element, a pre-amplifier, an off-set adjustment amplifier and a DC volt meter. The light source and light-receiving element are secured to the frame such that they face each other while keeping a gap therebetween such that an organism under measurement can be received in the gap without being urged. The pre-amplifier is connected to the light-receiving element and has a gain switching function. The summing amplifier is connected for zero adjustment and gain adjustment to the output side of the pre-amplifier and has an output terminal from which a DC data representing biopermeability is provided. Between the output terminal and ground the DC volt meter is connected.

Claims

1. An apparatus for measuring biopermeability comprising:

a frame;

light emitting means and light receiving means each secured to said frame to face each other while keeping a gap therebetween such that an organism under measurement can be received in said gap without being urged;

preamplifier means connected to said light receiving means;

amplifier means for zero adjustment and gain adjustment connected to an output of said preamplifier means, said amplifier means having an output for outputting data representing biopermeability;

display means for displaying biopermeability data connected between said output of said amplifier means and ground;

wherein said light emitting means is a light emitting diode; and

wherein said preamplifier means is an operational amplifier having two different selectable gains, one of said selectable gains being unity gain and the other 100 times gain;

an AC inverting amplifier circuit connected to said output of said amplifier means, and including a CR coupler and an amplifier having a fixed amplification factor, said AC inverting amplifier circuit having an output for outputting AC data.

2. The apparatus as claimed in claim 1, further comprising:

data processing means connected to said output of said amplifier means and said output of said AC inverting amplifier circuit, said data processing means automatically processing data output from said amplifier means and/or data output from said AC inverting amplifier circuit, and displaying the resulting processed data.

3. The apparatus as claimed in claim 2, wherein said data processing means comprises:

means for converting the output of said amplifier means and said AC inverting circuit data into respective digital data;

means for performing frequency analysis of the digital data output from the converting means;

means for storing waveform data and frequency spectra data obtained from said frequency analysis means;

display means for displaying said waveform data and frequency spectra data; and

control means for controlling the operation of said data processing means.

4. The apparatus as claimed in claim 1, wherein said amplifier means has an amplification factor of 50.

5. The apparatus as claimed in claim 1, wherein said AC inverting amplifier circuit includes an inverting amplifier connected to said output of said amplifier means, said inverting amplifier having an output for outputting said data of said AC inverting amplifier circuit.

6. The apparatus as claimed in claim 5, wherein said inverting amplifier has a unity amplification factor.

7. The apparatus as claimed in claim 1, further comprising:

switching means provided between said CR coupler and inverting amplifier to operably cause discharge of a capacitor provided in said CR coupler for zeroing the base line of measured waveforms.