Iontophoretic delivery device
First Claim
1. An electrically powered iontophoretic delivery device including a donor electrode assembly, a counter electrode assembly and a source of electrical power adapted to be electrically connected to the donor electrode assembly and the counter electrode assembly, at least one of the electrode assemblies including an agent reservoir containing an agent, the agent reservoir adapted to be placed in agent transmitting relation with a body surface, and an electrode adapted to be electrically connected to the source of electrical power and to the agent reservoir, wherein the electrode comprises:
- a polymeric matrix;
about 5 to 40% of a conductive filler forming a conductive network through the matrix; and
about 5 to 40 vol% of a chemical species able to undergo oxidation or reduction during operation of the device, the matrix having a plurality of fluid flow pathways therethrough.
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Accused Products
Abstract
An electrically powered iontophoretic delivery device is provided. The device utilizes electrodes composed of a polymeric matrix containing about 5 to 40 vol % of a conductive filler which forms a conductive network through the matrix, and about 5 to 40 vol % of a chemical species which is able to undergo either oxidation or reduction during operation of the device. Preferably, the conductive filler is carbon or graphite fibers. For the anode electrode, the chemical species should be able to undergo oxidation and is preferably either silver or zinc. For the cathode electrode, the chemical species should be able to undergo reduction and is preferably silver chloride.
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Citations
46 Claims
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1. An electrically powered iontophoretic delivery device including a donor electrode assembly, a counter electrode assembly and a source of electrical power adapted to be electrically connected to the donor electrode assembly and the counter electrode assembly, at least one of the electrode assemblies including an agent reservoir containing an agent, the agent reservoir adapted to be placed in agent transmitting relation with a body surface, and an electrode adapted to be electrically connected to the source of electrical power and to the agent reservoir, wherein the electrode comprises:
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a polymeric matrix; about 5 to 40% of a conductive filler forming a conductive network through the matrix; and about 5 to 40 vol% of a chemical species able to undergo oxidation or reduction during operation of the device, the matrix having a plurality of fluid flow pathways therethrough. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33)
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34. A method of activating a non-hydrated electrode assembly in an electrically powered iontophoretic delivery device, the device including a donor electrode assembly, a counter electrode assembly and a source of electrical power adapted to be electrically connected to the donor electrode assembly and the counter electrode assembly, at least one of the electrode assemblies including a non-hydrated agent reservoir containing an agent and an electrode, comprising:
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electrically connecting the electrode, which electrode is comprised of a polymeric matrix, about 5 to 40 vol% of a conductive filler forming a conductive network through the matrix and about 5 to 40 vol% of a chemical species able to undergo oxidation or reduction during operation of the device, to the source of electrical power and to the agent reservoir; forming a plurality of fluid flow pathways through the polymer matrix of the electrode; delivering a liquid solvent through the plurality of fluid flow pathways into the non-hydrated agent reservoir; and placing the agent reservoir in agent transmitting relation with a body surface. - View Dependent Claims (35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46)
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Specification