Methods for providing localized therapeutic heat to biological tissues and fluids
First Claim
Patent Images
1. A method for heat treating biological tissues and fluids which comprises:
- (i) administering to the tissue or fluid to be treated a therapeutically effective amount of a hyperthermia potentiator selected from the group consisting of gas, gaseous precursors and perfluorocarbons; and
(ii) applying ultrasound to heat said tissue or fluid to a temperature of at least about 43°
C.
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Abstract
Gas, gaseous precursors and prefluorocarbons are presented as novel potentiators for ultrasonic hyperthermia. The gas, gaseous precursors and perfluorocarbons which may be administered into the vasculature, interstitially or into any body cavity are designed to accumulate in cancerous and diseased tissues. When therapeutic ultrasonic energy is applied to the diseased region heating is increased because of the greater effectiveness of sound energy absorption caused by these agents.
461 Citations
14 Claims
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1. A method for heat treating biological tissues and fluids which comprises:
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(i) administering to the tissue or fluid to be treated a therapeutically effective amount of a hyperthermia potentiator selected from the group consisting of gas, gaseous precursors and perfluorocarbons; and (ii) applying ultrasound to heat said tissue or fluid to a temperature of at least about 43°
C. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification