Catheter-mounted doppler ultrasound transducer and signal processor

• US 5,156,157 A
• Filed: 03/08/1991
• Issued: 10/20/1992
• Est. Priority Date: 03/08/1991
• Status: Expired due to Term

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Telectronics Pacing Systems, Inc (Abbott Laboratories Incorporated)
• Inventors: Valenta, Harry L. Jr., Nappholz, Tibor A.
• Primary Examiner(s): Howell, Kyle L.
• Assistant Examiner(s): MANUEL, GEORGE C
• Application Number:
  US07/666,511
• Time in Patent Office: 592 Days
• Field of Search: 128/662.06, 128/419 PG, 128/642, 128/660.05, 128/661.04, 128/661.08, 128/661.1
• US Class Current: 600/463
• CPC Class Codes: A61B 8/06 Measuring blood flow measuring volume flow in general G01F, e.g. G01F1/66, G01F1/72; measuring speed of fluids in general G01P5/00
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/445 Details of catheter construction
• CPC Class Codes: A61N 1/36528 the parameter being measured by means of ultrasound
• CPC Class Codes: A61N 1/36571 controlled by blood flow rate, e.g. blood velocity or cardiac output

Abstract

A Doppler ultrasound transducer and interconnected high frequency signal processing circuit, adapted for operative coupling on a distal portion of an intravascular catheter, for ultrasonically sensing high frequency signals representative of blood flow within a patient'"'"'s cardiovascular system, processing these high frequency signals into baseband audio signals, and communicating these audio signals to associated low frequency signal processing circuitry located in the proximal portion of the catheter by modulating the load current of a power supply within the high frequency circuit.

Claims

1. A lead adapted to be coupled to a cardiac control or measurement device having a power source and a signal receiving means, for measuring blood flow in a patient'"'"'s cardiovascular system, comprising:

an elongate tube having a proximal portion adapted to be connected to said device and a distal portion adapted to be inserted into said cardiovascular system,

ultrasound transducer means affixed to said tube in the distal portion thereof, said ultrasound transducer means including an ultrasound transmitter and receiver circuit for transmitting ultrasonic frequency signals into the patient'"'"'body and receiving ultrasonic frequency echo signals from blood flowing therein,

means affixed to said tube in the distal portion thereof and electrically coupled to said transmitter and receiver circuit for processing said received ultrasonic frequency signals into audio frequency signals, and

insulated conductive means positioned within said elongate tube and extending between the distal portion thereof and the proximal portion thereof for, when coupled to said cardiac control or measurement device, delivering electrical power from said device power source to said processing means and communicating said audio frequency signals from said processing means to said device signal receiving means.

2. A lead according to claim 1, wherein said processing means further includes a switchable power supply means for selectively delivering electrical power from said processing means to said transmitting and receiving circuit.

3. A lead according to claim 2, wherein, when said lead is coupled to said cardiac control or measurement device and electrical power is delivered from said device power source to said processing means, a load current flows between said power supply means and said device, and wherein said processing means further includes means coupled to said power supply means for modulating said load current as a function of said audio frequency signals.

4. A lead according to claim 3, wherein said transmitter and receiver circuit further comprises a Doppler crystal and an oscillator circuit therein, and wherein said Doppler crystal is interconnected to said oscillator circuit to provide timing signals within said ultrasound transmitter and receiver circuit so that a reference frequency of said ultrasound transmitter and receiver circuit tracks the resonant frequency of said Doppler crystal.

5. A lead according to claim 3, wherein said transmitter and receiver circuit further comprises a Doppler crystal and an oscillator circuit therein, wherein said Doppler crystal is interconnected to said oscillator circuit to provide timing signals to said oscillator circuit, and wherein said oscillator circuit is a transconductance differential amplifier subcircuit within a doubly balanced modulator circuit.

6. A lead according to claim 5, wherein said processing means includes an amplifier, and wherein said amplifier is a matched voltage differential amplifier subcircuit within a doubly balanced modulator circuit.

7. A lead according to claim 6, wherein said oscillator circuit and said amplifier comprise two subcircuits within a single doubly balanced modulator circuit.

8. A lead according to claim 3, wherein said transmitter and receiver circuit includes a Doppler crystal therein, wherein said processing means includes an amplifier, wherein said Doppler crystal is interconnected to said amplifier to provide timing signals to said amplifier, and wherein said amplifier is a matched voltage differential amplifier subcircuit within a doubly balanced modulator circuit.

9. An ultrasound transducer and interconnected circuit for ultrasonically interrogating a patient'"'"'s cardiovascular system and converting received high frequency ultrasound signals into baseband audio signals, adapted for mounting and operative coupling to a catheter, comprising:

a switchable power supply controlled by signals communicated to it by said operatively coupled catheter, said power supply having a load current during operation,

a transmitter for transmitting ultrasonic frequency energy into the patient'"'"'s body, said transmitter being empowered by said switchable power supply,

a Doppler ultrasound signal detecting means for detecting ultrasound frequency Doppler signals from echoes arising from said ultrasonic transmissions and converting said ultrasound frequency Doppler signals into baseband audio signals,

means for modulating the load current of said switchable power supply to provide a signal which is a function of said audio frequency signals, and

a conductor for communicating the load current comprising the audio frequency function signal to said operatively coupled catheter.

10. A transducer and interconnected circuit according to claim 9, wherein said transmitter means is adapted to operate at a predetermined reference frequency and further comprises a Doppler crystal and an oscillator circuit therein, said Doppler crystal having a characteristic resonant frequency, and wherein said ultrasound signal detecting means is adapted to operate at said predetermined reference frequency, said Doppler crystal being coupled to said oscillator circuit to provide timing signals so that said predetermined reference frequency tracks the resonant frequency of said Doppler crystal.

11. A transducer and interconnected circuit according to claim 9, wherein said transmitter means for transmitting ultrasonic energy into the patient'"'"'s cardiovascular system further comprises a Doppler crystal and an oscillator circuit therein, wherein said Doppler crystal is interconnected to said oscillator circuit to provide timing signals to said oscillator circuit, and wherein said oscillator circuit is a transconductance differential amplifier subcircuit within a doubly balanced modulator circuit.

12. A transducer according to claim 11, wherein said transmitter for transmitting ultrasonic energy into the patient'"'"'s cardiovascular system includes an amplifier, and wherein said amplifier is a matched voltage differential amplifier subcircuit within a doubly balanced modulator circuit.

13. A transducer and interconnected circuit according to claim 12, wherein said oscillator circuit and said amplifier comprise two subcircuits within a single double balanced modulator.

14. A transducer and interconnected circuit according to claim 9, wherein said transmitter means for transmitting ultrasonic energy into the patient'"'"'s cardiovascular system includes an amplifier, and wherein said amplifier is a matched voltage differential amplifier subcircuit within a doubly balanced modulator circuit.

15. The combination of a lead and a cardiac control or measurement device, said device having a power source and a signal receiving means, said combination adapted to measure blood flow in a patient'"'"'s cardiovascular system, said lead comprising:

an elongated tube having a proximal portion adapted to be connected to said device and a distal portion adapted to be inserted into said cardiovascular system,

ultrasound transducer means affixed to said tube in the distal portion thereof, said ultrasound transducer means including an ultrasound transmitter and receiver circuit for transmitting ultrasonic frequency signals into the patient'"'"'s body and receiving ultrasound frequency echo signals from blood flowing therein,

means affixed to said tube in the distal portion thereof and electrically coupled to said transmitter and receiver circuit for processing said received ultrasonic frequency signals into audio frequency signals, and

insulated conductive means positioned within said elongate tube and extending between the distal portion thereof and the proximal portion thereof for delivering electrical power from said device power source to said processing means, and for communicating said audio frequency signals from said processing means to said device signal receiving means.

16. A combination according to claim 15, wherein said device further comprises means for selectively controlling the timing and voltage of the delivery of electrical power from said device power source to said processing means, and wherein said processing means further includes a switchable power supply means adapted to be selectively enabled and disabled in response to the delivery of electrical power from said device power source to said processing means.

17. A combination according to claim 16, wherein, responsive to the delivery of electrical power from said device power source to said processing means, a load current flows between said power supply means and said device, wherein said processing means further includes means coupled to said power supply means for modulating said load current as a function of said audio frequency signals, and wherein said device further includes means for measuring the load current.

18. A combination according to claim 15, wherein said cardiac control or measurement device includes means for controlling activation of said switchable power supply means within said processing means, wherein said cardiac control or measurement device senses timing of the patient'"'"'s cardiac cycle, and wherein said activation controlling means energizes said switchable power supply in synchrony with predetermined portions of the cardiac cycle.

19. A combination according to claim 15, wherein said cardiac control or measurement device further comprises means for controlling activation of said switchable power supply means and means for sensing the patient'"'"'s respiratory cycle timing, and wherein said activation controlling means energizes said switchable power supply in synchrony with predetermined portions of the respiratory cycle timing.

20. A combination according to claim 15, wherein said cardiac control or measurement device further comprises means for controlling activation of said switchable power supply means, means for sensing the patient'"'"'s cardiac cycle timing and means for sensing the patient'"'"'s respiratory cycle timing, and wherein said activation controlling means energizes said switchable power supply in synchrony with predetermined portions of the respiratory and cardiac cycle timing.