Neurological therapy system
First Claim
1. A neurological therapy device for the local and controlled delivery of a neurotransmitter to the brain of a subject, said device comprising a biocompatible, implanatble, and retrievable solid polymeric insert including a noncellular source of a neurotransmitter embedded within said insert for controlled linear release of said neurotransmitter from said insert by leaching.
2 Assignments
0 Petitions
Accused Products
Abstract
Neurological therapy devices are disclosed for the local and controlled delivery of a neurotransmitter to the brain of a subject suffering from neurotransmitter deficiency or dysfunction. In one embodiment the device includes a biocompatible, implantable, and retrievable polymeric insert including a source of neurotransmitter embedded therein. In another embodiment, the device includes a retrievable source of neurotransmitter including at least one neurotransmitter-secreting cell encapsulated within a semipermeable membrane allowing the diffusion therethrough of the neurotransmitter, and further includes a source of growth factor in close proximity to the neurotransmitter-secreting cells.
136 Citations
13 Claims
- 1. A neurological therapy device for the local and controlled delivery of a neurotransmitter to the brain of a subject, said device comprising a biocompatible, implanatble, and retrievable solid polymeric insert including a noncellular source of a neurotransmitter embedded within said insert for controlled linear release of said neurotransmitter from said insert by leaching.
Specification