Regional perfusion dissolution catheter

• US 5,163,905 A
• Filed: 05/21/1990
• Issued: 11/17/1992
• Est. Priority Date: 01/12/1990
• Status: Expired due to Term

• Current Assignee: Don Michael International, LLC
• Original Assignee: T. Anthony Don Michael
• Inventors: Don Michael, T. Anthony
• Primary Examiner(s): Rosenbaum, C. Fred
• Assistant Examiner(s): SMITH, CHALIN A
• Application Number:
  US07/526,260
• Time in Patent Office: 911 Days
• Field of Search: 604/21, 604/27, 604/28, 604/35, 604/36, 604/43, 604/44, 604/96-104, 606/191, 606/192, 606/194
• US Class Current: 604/101.03
• CPC Class Codes: A61B 2017/22084 stone- or thrombus-dissolving
• CPC Class Codes: A61M 2025/0057 Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 2025/1061 having separate inflations tubes, e.g. coaxial tubes or tubes otherwise arranged apart from the catheter tube
• CPC Class Codes: A61M 2025/1095 with perfusion means for enabling blood circulation while the balloon is in an inflated state or in a deflated state, e.g. permanent by-pass within catheter shaft
• CPC Class Codes: A61M 2025/1097 with perfusion means for enabling blood circulation only while the balloon is in an inflated state, e.g. temporary by-pass within balloon
• CPC Class Codes: A61M 25/0021 characterised by the form of the tubing A61M25/0054 takes precedence
• CPC Class Codes: A61M 25/0032 characterized by at least one unconventionally shaped lumen, e.g. polygons, ellipsoids, wedges or shapes comprising concave and convex parts
• CPC Class Codes: A61M 25/007 Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
• CPC Class Codes: A61M 25/0155 with hydraulic or pneumatic means, e.g. balloons or inflatable compartments
• CPC Class Codes: A61M 25/1011 Multiple balloon catheters

Abstract

A device for performing regional perfusion obstruction dissolution, composed of: an infusion catheter insertable into a blood vessel to extend across the site of an obstruction, the catheter having a length and extending in the direction of the length between a distal end via which the catheter is inserted into the blood vessel and a proximal end remote from the distal end, and the catheter being configured to have a blood bypass flow path extending along a portion of the length of the catheter and communicating with regions surrounding the catheter at first and second locations along the length of the catheter such that when the catheter extends across a clot site in a blood vessel, the first and second locations are positioned upstream and downstream, respectively, of the clot with respect to the direction of blood flow in the vessel, and a thrombolytic agent flow path extending along the length of the catheter from the proximal end and communicating with a region surrounding the catheter at a third location along the length of the catheter between the first and second locations for delivering thrombolytic agent to the clot when the catheter extends across the clot site in the blood vessel; a suction passage for withdrawing obstruction material from the obstruction site; and blocking devices secured to the catheters at locations which will enclose the obstruction site when the catheters are inserted, for blocking blood flow along a path exterior to the catheters.

Claims

1. A medical treatment device for removing obstructions in blood vessels by chemical dissolution, said device comprising:

a first elongate catheter having an outer surface and containing only two lumens, including a first lumen defining a passage having a cross section constituting a major portion of the cross section of said first catheter, and a second lumen defining a passage having a substantially smaller cross section than said first lumen, said first catheter having at least one first lateral passage and at least one second lateral passage communicating with said first lumen for permitting a flow of blood through said first lumen via said first and second lateral passages, extending to said outer surface and spaced apart along the length of said first catheter, and said first catheter further having a third lateral passage communicating with said second lumen and extending to said outer surface, said third lateral passage being located, along the length of said catheter, between said first and second lateral passages;

a balloon secured to said outer surface of said first catheter and having an opening communicating with said third lateral passage, said balloon being inflatable to close a blood vessel downstream of an obstruction; and

a second elongate catheter structurally separate from said first catheter and having a distal end and a lumen extending the entire length of said second catheter, emerging from said second catheter in the region of said distal end and defining a passage having a cross section constituting a major part of the cross section of said second catheter for conducting a fluid to or from the interior of the blood vessel adjacent the obstruction.

2. A method of removing an obstruction in a blood vessel, utilizing the device defined in claim 1, said method comprising:

introducing the first and second catheters into the blood vessels so that the third lateral passage is located downstream of the obstruction;

inflating the balloon in order to at least partially obstruct the interior of the blood vessel while allowing blood to flow through the first lumen, via the first and second lateral passages; and

alternatingly introducing a dissolution chemical to the site of the obstruction, and suctioning fluid from the site of the obstruction, via the lumen of the second catheter.

3. A medical treatment device as defined in claim 1 introduced into a blood vessel containing an obstruction which is to be removed, wherein:

said first catheter has a distal end, said second lateral passage is located in the vicinity of said distal end of said first catheter, said balloon is located between said first and second lateral passages, and said catheter is located so that the obstruction is positioned between said balloon and said first lateral passage;

said balloon is inflated to close the blood vessel; and

said second catheter is located so that said distal end of said second catheter communicates with a region within the blood vessel at which the obstruction is located.

4. A device as defined in claim 3 wherein said balloon is constructed to expand eccentrically relative to the longitudinal axis of said first catheter for urging said first catheter toward the wall of the blood vessel.

5. A device as defined in claim 1 wherein said balloon is constructed to expand eccentrically relative to the longitudinal axis of said first catheter for urging said first catheter toward the wall of a blood vessel in which said first catheter is inserted.

6. A device as defined in claim 1 wherein said second catheter contains only one lumen.