Ocular vial

• US 5,163,929 A
• Filed: 10/22/1990
• Issued: 11/17/1992
• Est. Priority Date: 03/13/1989
• Status: Expired due to Fees

• Current Assignee: Medinstill Development, LLC
• Original Assignee: Optic Inc.
• Inventors: Py, Daniel
• Primary Examiner(s): Isabella, David
• Assistant Examiner(s): BURKE, ELIZABETH
• Application Number:
  US07/601,944
• Time in Patent Office: 757 Days
• Field of Search: 604/294-302, 604/131-137, 222/420
• US Class Current: 604/298
• CPC Class Codes: A61F 9/0008 Introducing ophthalmic products into the ocular cavity or retaining products therein putting in contact lenses A61F9/0061; introducing or retaining media in cavities of the body in general A61M31/00
• CPC Class Codes: A61J 1/2027 having frangible parts
• CPC Class Codes: A61J 1/2093 Containers having several compartments for products to be mixed
• CPC Class Codes: A61M 11/00 Sprayers or atomisers specially adapted for therapeutic purposes in general B05B; aerosol containers B65D83/14
• CPC Class Codes: B65D 25/08 with provisions for removing or destroying, e.g. to facilitate mixing of contents
• CPC Class Codes: B65D 81/3222 with additional means facilitating admixture

Abstract

An ocular treatment apparatus for applying medicament into an eye has a vial defining a vial cavity for holding medicament. A nozzle is attached over an opening in the vial and is in fluid communication with the vial cavity for releasing drops of medicament. A piston member is suspended within the vial and slideably engaged within the vial cavity for displacing a substantially predetermined volume of medicament through the nozzle for release into the eye.

Claims

1. An ocular treatment apparatus for applying medicament into an eye, said apparatus comprising:

a nozzle having an orifice defined therein for releasing medicament into the eye;

storage means including a storage cavity in fluid communication with said nozzle orifice for holding medicament for release into the eye;

a vial defining a first cavity for holding a first medicament, said first cavity being in fluid communication with said storage cavity, said vial further defining a second cavity for holding a second medicament;

means for controllably placing said first cavity of said vial in fluid communication with said second cavity of said vial for mixing in said storage cavity the first and second medicaments into a mixed medicament; and

displacement means for displacing a substantially predetermined volume of mixed medicament within said storage cavity through said nozzle orifice for release into the eye.

2. An ocular treatment apparatus as defined in claim 1, wherein

said displacement means comprises a piston member, said piston member being engageable within said storage cavity for displacing mixed medicament through said nozzle orifice for release into the eye.

3. An ocular treatment apparatus as defined in claim 1, wherein

said displacement means includes a piston member, said piston member being engageable within said storage cavity for displacing medicament within said storage cavity through said nozzle orifice for release into the eye.

4. An ocular treatment apparatus as defined in claim 1, wherein

said displacement means displaces a single drop of medicament each time said displacement means displaces medicament within said storage means, through said nozzle orifice, for release into the eye.

5. An ocular treatment apparatus for applying medicament into an eye, said apparatus comprising:

a nozzle having an orifice defined therein for releasing medicament into the eye and defining a nozzle cavity coupled in fluid communication with said orifice for receiving medicament for release into the eye;

a vial including an outer shell and an inner shell, said inner shell being joined to said outer shell and moveable relative thereto, said outer shell defining a first cavity for holding a first medicament, said first cavity being in fluid communication with said nozzle cavity, and said inner shell defining a second cavity for holding a second medicament;

means for controllably placing said first cavity of said vial in fluid communication with said second cavity of said vial for mixing in said nozzle cavity the first and second medicaments into a mixed medicament; and

displacement means for displacing a substantially predetermined volume of mixed medicament within said nozzle cavity through said nozzle orifice for release into the eye, said displacement means including a piston member coupled to said inner shell and engageable within said nozzle cavity by depressing said inner shell relative to said outer shell for displacing medicament within said nozzle cavity through said nozzle orifice for release into the eye.

6. An ocular treatment apparatus as defined in claim 5, wherein said means for controllably placing said first and second cavities of said vial in fluid communication comprises:

at least one pin member, said pin member protruding inwardly from an interior surface of said outer shell such that when said inner shell is depressed relative to said outer shell, said pin member pierces a wall defining said second cavity for holding a second medicament, thus placing said first and second cavities in fluid communication for mixing the first and second medicaments into a mixed medicament.

7. An ocular treatment apparatus for applying medicament into an eye, said apparatus comprising:

a nozzle having an orifice defined therein for releasing medicament into the eye;

storage means in fluid communication with said nozzle orifice for holding medicament for release into the eye;

a vial defining a first cavity for holding a first medicament, said first cavity being in fluid communication with said storage means, said vial further defining a second cavity for holding a second medicament;

means for controllably placing said first cavity of said vial in fluid communication with said second cavity of said vial for mixing in said storage means the first and second medicaments into a mixed medicament, wherein said second cavity for holding the second medicament is evacuated to a subatmospheric pressure for facilitating the mixing of the first and second medicaments; and

displacement means for displacing a substantially predetermined volume of mixed medicament with said storage means through said nozzle orifice for release into the eye.

8. An ocular treatment apparatus for applying medicament into an eye, comprising:

a nozzle defining an orifice for releasing medicament into the eye;

storage means in fluid communication with said nozzle orifice for holding medicament for release into the eye;

displacement means for displacing a substantially predetermined volume of medicament within said storage means through said nozzle orifice for release into the eye;

a body, said body defining a first cavity for holding a first medicament, said first cavity being in fluid communication with said storage means, said body further defining a second cavity for holding a second medicament wherein said body defines a first shell and a second shell, said second shell being joined to said first shell and movable relative thereto, said first and second shells defining therebetween said first cavity for holding a first medicament, and said second shell defining said second cavity for holding a second medicament; and

means for controllably placing said first cavity of said body in fluid communication with said second cavity of said body for mixing in said storage means the first and second medicaments into a mixed medicament solution.

9. An ocular treatment apparatus as defined in claim 8, wherein

said displacement means comprises a piston member, said piston member being engageable within said storage means for displacing medicament through said nozzle orifice.

10. An ocular treatment apparatus as defined in claim 9, wherein

said piston member is suspended from said second shell and within said first shell, said piston member being engageable within said storage means by moving said second shell relative to said first shell for displacing medicament through said nozzle orifice.

11. An ocular treatment apparatus as defined in claim 8, wherein said means for controllably placing said first cavity and said second cavity of said body in fluid communication includes:

at least one pin member, said pin member protruding inwardly from an interior surface of said first shell such that when said second shell is moved relative to said first shell, said pin member pierces a wall defining said second cavity, thus placing said first and second cavities in fluid communication for mixing the first and second medicaments into a mixed medicament.

12. An ocular treatment apparatus for applying medicament into an eye, said apparatus comprising:

a nozzle defining an orifice for releasing medicament into the eye;

a storage portion coupled in fluid communication with said nozzle orifice for holding medicament for release into the eye;

a body member defining a first cavity for holding a first medicament, said first cavity being in fluid communication with said storage portion, said body further defining a second cavity for holding a second medicament;

means for placing said first cavity of said body member in fluid communication with said second cavity of said body member for mixing in said storage portion the first and second medicaments into a mixed medicament solution; and

a piston member for displacing a substantially predetermined volume of medicament within said storage portion through said nozzle orifice for release into the eye.

13. An ocular treatment apparatus as defined in claim 12, wherein

said storage portion includes a nozzle cavity defined within said nozzle, said nozzle cavity being in fluid communication with both said nozzle orifice and with said first cavity of said body member, said piston member being engageable within said nozzle cavity for displacing medicament therein through said nozzle orifice for release into the eye.

14. An ocular treatment apparatus as defined in claim 12, wherein said body member includes a first portion defining said first cavity and a second portion defining said second cavity, said first and second portions being movable relative to each other.

15. An ocular treatment apparatus as defined in claim 14, wherein said piston member is coupled to said first portion and movable with said first portion relative to said second portion for displacing a substantially predetermined volume of medicament from said storage portion.

16. An ocular treatment apparatus as defined in claim 12, wherein said means for placing said first cavity in fluid communication with said second cavity includes a piercing member for piercing a wall defining at least one of said cavities to couple said first and second cavities in fluid communication.