Liquid-vapor pressure reservoir for medication infusion pump

• US 5,167,633 A
• Filed: 11/29/1990
• Issued: 12/01/1992
• Est. Priority Date: 11/29/1990
• Status: Expired due to Term

• Current Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Inventors: Mann, Alfred E., Lord, Peter C.
• Primary Examiner(s): Mancene, Gene
• Assistant Examiner(s): LAVIOLA JR, FRANK
• Application Number:
  US07/619,650
• Time in Patent Office: 733 Days
• Field of Search: 604/93, 604/131, 604/141, 604/145, 604/151, 604/890.1, 604/891.1, 604/892.1, 128/DIG. 12
• US Class Current: 604/141
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: Y10S 128/12 Pressure infusion

Abstract

An improved and simplified pressure reservoir is provided for use with an implantable medication infusion pump to maintain a selected medication in liquid form with a pump housing under a substantially constant pressure. The pressure reservoir comprises a hollow structural enclousre having at least one flexible resilient wall and is adapted to be filled with a selected quantity of a pressure fluid, such as a selected fluorocarbon in a liquid-vapor state, prior to mounting of the reservoir as a structural unit into the infusion pump housing. Within the pump housing, the flexible reservoir wall defines one side of a medication chamber, with the pressure fluid undergoing appropriate change of state to expand or contact the reservoir in a manner maintaining the medication under a substantially constant pressure. The improved reservoir can be provided in a variety of structural shapes and/or utilized in pump housings of various size and shape to permit the pump size to be reduced, or, in the alternative, to increase pump medication capacity without increasing pump housing size.

Claims

1. A pressure reservoir for use in an implantable medication infusion pump of the type having a hermetically sealed housing with a medication chamber for receiving a supply of a selected liquid medication disposed therein, the medication infusion pump also having pump means disposed within said housing for delivering the medication from the medication chamber to a patient, said pressure reservoir comprising:

a structural enclosure having a selected liquid-vapor pressure fluid therein, said structural enclosure being mounted within the housing and defining at least one flexible movable wall exposed to the medication chamber, said pressure fluid being adapted to undergo sufficient liquid-vapor phase change for varying the volumetric size of said structural enclosure in response to the quantity of the medication within the medication chamber to maintain the medication under a predetermined and substantially constant pressure, wherein said pressure fluid is selected to maintain the medication chamber under a pressure less than atmospheric pressure.

2. A pressure reservoir as defined in claim 1, wherein said movable wall of said structural enclosure is formed from a flexible, impermeable, medication and pressure fluid compatible material.

3. A pressure reservoir as defined in claim 2, wherein said movable wall of said structural enclosure is formed from Halar film material.

4. A pressure reservoir as defined in claim 1, wherein said structural enclosure is formed as an expansible bag.

5. A pressure reservoir as defined in claim 4, wherein said expansible bag comprises:

a pair of plastic film sheets interconnected about the peripheries thereof to define a hollow bag interior for receiving said pressure fluid.

6. A pressure reservoir as defined in claim 1, further comprising:

means for securing said structural enclosure within the housing.

7. A pressure reservoir as defined in claim 1, wherein said pressure fluid comprises a selected fluorocarbon.

8. A pressure reservoir as defined in claim 7, wherein said pressure fluid comprises Freon 113.

9. A pressure reservoir for use in an implantable medication infusion pump of the type having a hermetically sealed housing with a medication chamber for receiving a supply of a selected liquid medication disposed therein, the medication infusion pump also having pump means disposed within said housing for delivering the medication from the medication chamber to a patient, said pressure reservoir comprising:

means defining an expansible structural enclosure having a liquid-vapor pressure fluid therein, said structural enclosure defining at least one flexible movable wall exposed to the medication chamber, said pressure fluid being adapted to undergo sufficient liquid-vapor phase change for varying the volumetric size of said structural enclosure in response to the quantity of the medication within the medication chamber to maintain the medication under a predetermined and substantially constant pressure, wherein said pressure fluid is selected to maintain the medication chamber under a pressure less than atmospheric pressure.

10. A pressure reservoir as defined in claim 9, wherein said movable wall of said structural enclosure is formed from a flexible, impermeable, medication and pressure fluid compatible material.

11. A pressure reservoir as defined in claim 9, wherein said structural enclosure is formed as an expansible bag.

12. A pressure reservoir for use in an implantable medication infusion pump of the type having a hermetically sealed housing with a medication chamber for receiving a supply of a selected liquid medication disposed therein, the medication infusion pump also having pump means disposed within said housing for delivering the medication from the medication chamber to a patient, said pressure reservoir comprising:

a structural enclosure having a selected liquid-vapor pressure fluid therein, said structural enclosure being mounted within the medication chamber and defining at least one flexible movable wall exposed to the medication chamber, said pressure fluid being adapted to undergo sufficient liquid-vapor phase change for varying the volumetric size of said structural enclosure in response to the quantity of the medication within the medication chamber to maintain the medication under a predetermined and substantially constant pressure, wherein said pressure fluid is selected to maintain the medication chamber under a pressure less than atmospheric pressure.

13. A pressure reservoir as defined in claim 12, wherein said movable wall of said pressure reservoir is formed from a flexible, impermeable, medication and pressure fluid compatible material.

14. A pressure reservoir as defined in claim 12, wherein said pressure reservoir is formed as an expansible bag.

15. A pressure reservoir for use in an implantable medication infusion pump of the type having a hermetically sealed housing with a medication chamber for receiving a supply of a selected liquid medication disposed therein, the medication infusion pump also having pump means disposed within said housing for delivering the medication from the medication chamber to a patient, said pressure reservoir comprising:

a pillow-shaped member having two sides made of a flexible material sealed about the periphery thereof to enclose a selected liquid-vapor pressure fluid therein, said pillow-shaped member being located within the medication chamber and defining a volumetric size within the medication chamber, said pressure fluid being adapted to undergo sufficient liquid-vapor phase change for varying the volumetric size of said pillow-shaped member in response to the quantity of the medication within the medication chamber to maintain the medication under a predetermined and substantially constant pressure, wherein said pressure fluid is selected to maintain the medication chamber under a pressure less than atmospheric pressure.

16. A medication infusion pump, comprising:

a pump housing having a medication chamber formed therein for receiving a supply of a selected medication;

pump means within said housing for delivering the medication from said medication chamber to a patient; and

a pressure reservoir comprising a structural enclosure and having a selected liquid-vapor pressure fluid therein, said pressure reservoir being mounted within said pump housing and defining a movable wall exposed to said medication chamber, said pressure fluid being adapted to undergo sufficient liquid-vapor phase change for varying the volumetric size of said pressure reservoir in response to the quantity of the medication within said medication chamber to maintain the medication under a predetermined and substantially constant pressure.

17. A medication infusion pump as defined in claim 16, wherein said pump housing is hermetically sealed to permit direct implantation into the body of a patient.

18. A medication infusion pump as defined in claim 16, wherein said movable wall of said pressure reservoir is formed from a flexible, impermeable, medication and pressure fluid compatible material.

19. A medication infusion pump as defined in claim 16, wherein said pressure reservoir is formed as an expansible bag.

20. A medication infusion pump as defined in claim 19, wherein said expansible bag comprises a pair of plastic film sheets interconnected about the peripheries thereof to define a hollow bag interior for receiving said pressure fluid.

21. A medication infusion pump as defined in claim 16, wherein said pump means includes an intake port in communication with said medication chamber, and further including means for preventing said pressure reservoir from obstructing said intake port.

22. A medication infusion pump as defined in claim 16, further including means for securing said pressure reservoir within said pump housing.

23. A medication infusion pump as defined in claim 16, wherein said pressure fluid is a selected fluorocarbon.

24. A method of maintaining a selected pressure in a medication chamber contained in an implantable liquid medication infusion pump, said method comprising:

filling a structural enclosure having at least one flexible wall with a selected liquid-vapor pressure fluid; and

installing said structural enclosure within the medication chamber, said pressure fluid being adapted to undergo sufficient liquid-vapor phase change for varying the volumetric size of said structural enclosure in response to the quantity of the medication within the medication chamber to maintain the medication under a predetermined and substantially constant pressure, wherein said pressure fluid is selected to maintain the medication chamber under a pressure less than atmospheric pressure.