Pressure-activated medication dispenser

• US 5,169,388 A
• Filed: 06/07/1990
• Issued: 12/08/1992
• Est. Priority Date: 06/07/1990
• Status: Expired due to Fees

• Current Assignee: McGaw, Inc. (B. Braun Holding GmbH & Co. KG)
• Original Assignee: Gensia Pharmaceuticals, Inc. (Teva Pharmaceutical Industries Limited)
• Inventors: McPhee, Charles J.
• Primary Examiner(s): Hafer, Robert A.
• Assistant Examiner(s): Rimell, Sam
• Application Number:
  US07/535,396
• Time in Patent Office: 915 Days
• Field of Search: 604/403, 604/411, 604/412, 604/414, 604/415, 604/416, 604/89, 604/90, 604/91
• US Class Current: 604/90
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2089 Containers or vials which are to be joined to each other in order to mix their contents combinations of vial and syringe for mixing their contents A61J1/2096

Abstract

A drug dispenser comprising a drug vial to whose neck a hollow spike is attached for insertion into a diluent container, with a jaw around the spike grasping the inlet port of the container. A stopper seals the vial'"'"'s throat, and a two-way value covers its mouth. The valve is opened, and the stopper is blown from the vial'"'"'s throat by squeezing the diluent container, thereby sending diluent under pressure through the hollow spike, the open valve, and the unobstructed throat into the vial.

Claims

1. A drug dispenser adapted to be sealingly connected to a pressurizable diluent container so as to transfer diluent between said container and said drug dispenser, comprising in combination:

(a) a drug vial having a neck and a throat within said neck;

(b) a stopper seated in and sealing said throat;

(c) a normally closed valve adjacent to and extending over said stopper and further sealing said throat; and

(d) means for effecting pressurized communication between said container and said drug dispenser, said drug dispenser being characterized in that said valve can be opened and said stopper can be dislodged from said throat by pressurizing said container.

2. The drug dispenser of claim 1, wherein said stopper is covered with an anti-friction coating to minimize variation in the container pressure required to dislodge said stopper.

3. The drug dispenser of claim 1, wherein said stopper is formed of an elastomer.

4. The drug dispenser of claim 3, wherein said stopper is formed of butyl rubber.

5. The drug dispenser of claim 1, wherein the pressure required to dislodge said stopper is greater than that required to open said valve.

6. The drug dispenser of claim 5, wherein the pressure required to dislodge said stopper does not exceed 10 pounds per square inch.

7. The drug dispenser of claim 1, wherein said container is a deformable bag which is pressurizable by manual squeezing, and wherein the pressure required to dislodge said stopper does not exceed that which can be developed by squeezing said container.

8. The drug dispenser of claim 7, wherein said pressure does not exceed about 10 pounds per square inch.

9. A drug dispenser adapted to be sealingly connected to a pressurized diluent container so as to transfer diluent between said container and said drug dispenser, comprising in combination:

(a) a drug vial having a neck and a throat within said neck;

(b) a stopper comprising a hollow cylinder divided by a radially-extending wall into first and second cylindrical wall portions respectively defining first and second chambers open in axially-opposite directions and terminating in first and second rims respectively, seated in and sealing said throat;

(c) a normally closed valve extending over said stopper and further sealing said throat; and

(d) means for effecting pressurized communication between said container and said drug dispenser, said drug dispenser being characterized in that said valve can be opened and said stopper can be dislodged from said throat by pressurizing said container.

10. The drug dispenser of claim 9, wherein the second of said chambers has an opening in its cylindrical wall portion extending axially from the rim of said second chamber towards said wall.

11. The drug dispenser of claim 10, wherein said first wall portion is outwardly flared so as to provide a sealing skirt for engaging said drug vial throat.

12. A drug dispenser adapted to be sealingly connected to a pressurizable diluent container which includes a neck having a port sealed by a penetratable stopper and surrounded by a peripheral rim, so as to transfer diluent between said container and said drug dispenser, comprising in combination;

(a) a drug vial having a neck and a throat within said neck;

(b) a stopper seated in and sealing said throat;

(c) a normally closed valve extending over said stopper and further sealing said throat;

(d) a spike having an axially-extending bore in at least one opening extending through the wall of said spike from said bore, said spike permitting pressurized communication between said container and said drug dispenser, and

(e) a jaw member having a set of axially-extending resilient arms surrounding said spike and extending generally parallel therewith, said arms terminating in reentrant teeth adapted to latch onto said rim when said spike is jabbed through said penetratable stopper,

said drug dispenser being characterized in that said valve can be opened and said stopper can be dislodged from said throat by pressurizing said container.

13. The drug dispenser of claim 12, wherein said container is a deformable bag which is pressurizable by squeezing, and wherein the pressure required to dislodge said plug can be developed by manual squeezing of said bag.

14. The drug dispenser of claim 13, wherein the pressure required to dislodge said plug does not exceed about 10 pounds per square inch.

15. The drug dispenser of claim 14, wherein the pressure required to open said valve is less than that required to dislodge said plug.

16. The drug dispenser of claim 15, wherein said valve is formed of a disk having a central member with a single diametrically-extending slit therein.

17. The drug dispenser of claim 15, wherein said drug vial, said valve, and spike, and said jaw member each includes a peripheral flange, wherein said flanges are stacked in the order of the drug vial, valve, spike and jaw, and are held rigidly fastened in their stacked positions by a retaining hoop which encircles all of them.

18. The drug dispenser of claim 17 additionally including a protective cap having a reduced-diameter tip for enclosing said spike, an enlarged-diameter base dimensioned to snugly fit around the outside of said jaw member, said protective cap having an inner circumferential groove extending around its base, and said hoop terminating in an outwardly-curling rim which snaps into said inner circumferential groove when said protective cap is fitted onto said jaw member.