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Surgical adhesive

  • US 5,173,301 A
  • Filed: 11/27/1991
  • Issued: 12/22/1992
  • Est. Priority Date: 11/27/1990
  • Status: Expired due to Term
First Claim
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1. A surgical adhesive which comprises at least one NCO-terminated hydrophilic urethane prepolymer, derived from (a) an organic polyisocyanate and (b) a polyol component comprising at least one polyester polyol derived from a dicarboxylic acid represented by the general formula:

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    space="preserve" listing-type="equation">HOOC--(A).sub.m --COOH (1)wherein m is 0 or 1, A is --CH2 -- or an electron attracting group represented by the formula;

    --R--CO-- or ##STR2## R is a divalent hydrocarbon group containing 1-8 carbon atoms, R'"'"' is a divalent hydrocarbon group or halogen-substituted hydrocarbon group containing 1-8 carbon atoms, X is a halogen atom or nitro or cyano group, Y is hydrogen atom, a halogen atom or nitro or cyano group, n is 0, 1 or 2, wherein the polyester polyols derived from a dicarboxylic acid have an equivalent weight of 20-1000, the ratio of NCO/OH is 1.5 or more, and the NCO content of the NCO-terminated hydrophilic urethane prepolymer is 1-10%.

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