Sensor for right ventricular and thoracic volumes using the trailing edge value of a generated pulse

• US 5,174,286 A
• Filed: 12/07/1990
• Issued: 12/29/1992
• Est. Priority Date: 12/07/1990
• Status: Expired due to Term

• Current Assignee: Dr. Raul Chirife
• Original Assignee: Dr. Raul Chirife
• Inventors: Chirife, Raul
• Primary Examiner(s): Howell, Kyle L.
• Assistant Examiner(s): SCHAETZLE, KENNEDY
• Application Number:
  US07/623,576
• Time in Patent Office: 753 Days
• Field of Search: 128/419 D, 128/419 PG, 128/419 PT, 128/713, 128/734, 128/723
• US Class Current: 607/11
• CPC Class Codes: A61N 1/36514 controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by two or more physical parameters A61N1/36585

Abstract

A sensor for developing a control signal to be injected into the mechanism of a cardiac diagnosis and therapy device is disclosed. An external or internal pulse generator associated with the sensor includes a pulse width timer and an oscillator circuit to deliver constant voltage pulses through a capacitor to a lead for delivery of therapy or diagnosis. Means for detecting the peak trailing edge voltage or the current are included as an indicator of the volume of blood present in the heart or the thoracic volume at the time of stimulation. The volume signal is then directed to implantable or external devices by a control signal output to be used in the circuit of the other device.

Claims

1. Apparatus for applying therapy to a patient, comprising in combination:

(a) pulse generator means for producing square wave pulses;

(b) stimulating lead means for applying stimulating pulses to body tissues;

(c) capacitor means connected to said pulse generator means for delivering said square wave pulses to said lead means;

(d) integrator means coupled to said capacitor means for determining a parameter of a trailing edge signal resultant from said square wave pulses, said integrator means including a reset means for terminating integration of said trailing edge signal;

(e) peak detector means connected to said integrator means for detecting a maximum value achieved of said parameter of said trailing edge signal; and

(f) means connected to said peak detector means for outputting the peak detected maximum value.

2. The apparatus as in claim 1, wherein said reset means includes means for removing antifact by developing a control signal from a fixed percentage of said square wave pulse.

4. The apparatus as in either claim 1 or claim 3 wherein said stimulating lead means is a bipolar lead.

5. The apparatus as in either claim 1 or claim 3, wherein said stimulating lead means is a unipolar lead.

3. Apparatus for applying therapy to a patient, comprising in combination:

(a) pulse generator means for producing square wave pulses;

(b) stimulating lead means for applying stimulating pulses to body tissue;

(c) capacitor means connected to said pulse generator means for delivering said square wave pulses to said lead means;

(d) integrator means coupled to said capacitor means for determining a trailing edge voltage resultant form said square wave pulses, said integrator means including a reset means for terminating integration of said trailing edge voltage;

(e) voltage peak detector means connected to said integrator means for detecting the maximum voltage achieved for said trailing edge voltage; and

(f) means connected to said voltage peak detector means for outputting the peak detected trailing edge voltage signal.

6. The apparatus as in claim 3, wherein said reset means includes means for removing antifact by developing a control signal from a fixed percentage of said square wave pulse.

7. A method of producing a control signal for an apparatus for applying treatment to a patient comprising:

(a) producing an output signal pulse;

(b) applying said output signal pulse to tissue of the patient to be stimulated by way of a coupling capacitor and a stimulating lead;

(c) sensing a parameter of a trailing edge signal resultant from said output signal pulse developed across said coupling capacitor; and

(d) using the sensed parameter of the trailing edge signal to determine an intracardiac volume of the patient.

8. A method as in claim 7 wherein said treatment is cardiac pacing.

9. A method as in claim 7 wherein said treatment is drug delivery.

10. The method of claim 7 further comprising the step of:

(e) using the sensed parameter of the trailing edge signal to determine an intrathoracic volume of the patient.

11. In an implantable cardiac rhythm management device of the type comprising pulse generating means for producing output pulses and means including an output capacitor and a pacing lead for coupling said output pulses to tissue of a patient to be stimulated, said device including an improved physiologic sensor comprising:

(a) means for deriving a control signal corresponding to a parameter of a trailing edge signal resultant from the pulse signals applied to said tissue; and

(b) means for determining an intracardiac volume of a patient the device is adapted to as a function of said control signal and providing a first output indicative thereof.

12. The device as specified in claim 11 wherein said determining means further comprises means for determining stroke volume of a heart of the patient the device is adapted to as a function of said first output.

13. The device as specified in claim 11 wherein said determining means further comprises means for determining cardiac output of a heart of the patient the device is adapted to as a function of said first output.

14. The device as specified in claim 11 wherein said determining means further comprises means for determining ventricular ejection fraction of a heart of the patient the device is adapted to as a function of said first output.

16. The device as specified in claim 11 or 15 wherein said determining means adjusts a characteristic of said output pulses from said pulse generating means as a function of said first output.

15. In an implantable cardiac rhythm management device of the type comprising pulse generating means for producing output pulses and means including an output capacitor and a pacing lead for coupling said output pulses to tissue of a patient to be stimulated, said device including an improved physiologic sensor comprising:

(a) a means for deriving a control signal corresponding to a parameter of a trailing edge signal resultant from the pulse signals applied to the tissue; and

(b) means for determining a thoracic volume of a patient the device is adapted to as a function of said control signal and providing a first output indicative thereof.

17. The device as specified in claim 15 wherein said determining means further comprises means for determining tidal volume of the patient the device is adapted to as a function of the first output.

18. The device as specified in claim 15 wherein said determining means further comprises means for determining minute ventilation of the patient the device is adapted to as a function of the first output.

19. A method of cardiac monitoring a patient comprising:

(a) producing an output signal pulse;

(b) applying said output signal pulse to tissue of the patient to be stimulated by way of a coupling capacitor and a stimulating lead;

(c) sensing a parameter of a trailing edge signal resultant from said output signal pulse developed across said coupling capacitor;

(d) using the sensed parameter of the trailing edge signal to determine an intracardiac volume of the patient; and

(e) producing a first output signal indicative of the determined intracardiac volume for monitoring of the patient.