Preparation of stable polyvinyl alcohol hydrogel contact lens

• US 5,174,929 A
• Filed: 08/31/1990
• Issued: 12/29/1992
• Est. Priority Date: 08/31/1990
• Status: Expired due to Fees

• Current Assignee: Ciba-Geigy Corporation (Novartis Ag)
• Original Assignee: Ciba-Geigy Corporation (Novartis Ag)
• Inventors: Lee, Ping I., Janssen, Robert A., Ajello, Ellen M.
• Primary Examiner(s): Schofer, Joseph L.
• Assistant Examiner(s): REDDICK, MARIE L
• Application Number:
  US07/576,624
• Time in Patent Office: 851 Days
• Field of Search: 524/388, 524/503, 524/557, 523/106, 264/1.1, 264/2.6, 264/2.7
• US Class Current: 264/2.6
• CPC Class Codes: C08L 29/00 Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers
• CPC Class Codes: G02B 1/043 Contact lenses

Abstract

A dimensionally stable hydrogel contact lens of polyvinyl alcohol having an equilibrium water content of between about 70 to about 80 weight percent, based upon the total swollen lens weight, said lens having been annealed in a mold essentially conforming to the contact lens dimensions under substantially ambient non-drying setting conditions in the presence of an aqueous-organic annealing promoter solvent, for a period of time substantially sufficient to reach annealing equilibrium.

Claims

1. A method of preparing a dimensionally stable contact lens of polyvinyl alcohol having an equilibrium water content of between 70 to about 80 weight percent, based upon the swollen lens weight, comprising providing a casting solution containing about 18 to about 35% polyvinyl alcohol in an aqueous-organic annealing promoter solvent, placing said solution in a mold essentially conforming to the final contact lens dimensions under substantially ambient non-drying setting conditions for a period of time sufficient to reach annealing equilibrium, removing the annealed lens from the mold, removing the organic annealing promoter solvent by washing the lens with an aqueous solution, and recovering the contact lens.

2. A method according to claim 1 wherein the lens is annealed at a temperature between about 15°

C. to about 30°

C. for between about 20 hours and about 45 days.

3. A method according to claim 2, wherein the casting solution consists essentially of about 10% to about 60% by weight annealing promoter, about 18 to about 30% by weight polyvinyl alcohol and the remainder water.

4. A method according to claim 3, wherein the promoter is glycerine.