Blood glucose reflectance meter including a null prompting means and a device for providing a constant brightness light

• US 5,174,963 A
• Filed: 01/07/1991
• Issued: 12/29/1992
• Est. Priority Date: 01/07/1991
• Status: Expired due to Fees

• Current Assignee: UMM Electronics, Inc. (Nortech Systems, Inc.)
• Original Assignee: United Medical Manufacturing Co. (Nortech Systems, Inc.)
• Inventors: Riedel, Richard A., Fuller, Maurice D.
• Primary Examiner(s): Hill, Jr., Robert J.
• Application Number:
  US07/638,170
• Time in Patent Office: 722 Days
• Field of Search: 422/56, 422/68.1, 422/82.01, 422/82.02, 422/82.05, 422/82.12, 436/95, 436/169, 356/446, 250/238
• US Class Current: 422/82.05
• CPC Class Codes: G01N 21/274 Calibration, base line adjustment, drift correction
• CPC Class Codes: G01N 21/8483 Investigating reagent band test-element handling not specific to a test method G01N33/4875; analytical elements specific to chemical analysis of biological material G01N33/52; autometer with reagent band G01N35/04
• CPC Class Codes: G01N 2201/1211 for temperature
• CPC Class Codes: G01N 2201/12738 Selectively initiating check
• CPC Class Codes: Y10T 436/144444 Glucose

Abstract

A portable blood glucose monitoring meter that employs an analog circuit in conjunction with a manually rotatable dial that varies the resistance of a potentiometer to locate a null position that balances the measure taken of the blood glucose-induced changes in the chemistries of disposable test strips. The dial supports a replaceable, pre-printed, man-readable calibration disk. The calibration disk displays in man-readable format blood glucose concentrations in milligrams per milliliter calibrated to the specific batch-lot chemistries of the disposable test strips used with the meter. A patient places a replaceable batch-lot calibration disk upon the dial, and inserts a corresponding test strip bearing a drop of capillary blood into the meter. The patient then manually adjusts the dial until prompting arrows indicate a null position. If the dial has rotated past the null position, an opposing arrow will illuminate indicating a need to rotate the dial in the opposite direction. The procedure is repeated until a null position is found. At the null position, the prompting arrows illuminate simultaneously. The concentration of the patient'"'"'s blood glucose in milligrams per milliliter is then read directly from the number appearing on the calibration disk at the null point.

Claims

1. In a portable blood glucose monitoring meter having an analog circuit with a variable potentiometer to measure blood glucose-induced changes in the chemistries of disposable test strips to determine blood glucose concentrations, the improvements comprising:

dial means to vary manually the resistance of said potentiometer to locate a null position that balances the measure of the blood glucose-induced changes in the chemistries of disposable test strips;

calibration means integral with said dial means to receive replaceable, pre-printed, man-readable blood glucose concentrations that correspond to the null positions located by said dial means and that are empirically calibrated to the batch lot variations in the chemistries of the disposable test strips used in the meter; and

null prompting means to indicate the manual variation of said dial means required to achieve a null position.

2. The portable blood glucose monitoring meter of claim 1 wherein said dial means includes a manually rotatable dial.

3. The portable blood glucose monitoring meter of claim 2 wherein said manually rotatable dial supports a replaceable, man-readable, pre-printed calibration disk.

4. The portable blood glucose monitoring meter of claim 3 wherein said calibration disk displays man-readable blood glucose concentrations in milligrams per milliliter about its periphery that are calibrated by their position about the periphery to the specific batch-lot chemistries applied to the disposable test strips to be used with the meter.

5. The portable blood glucose monitoring meter of claim 1 wherein said null prompting means is non-linear and includes display means that indicate the direction of manual variation of said potentiometer required to locate a null position.

6. The portable blood glucose monitoring meter of claim 5 wherein said display means includes at least two illuminating indicators.

7. The portable blood glucose monitoring meter of claim 6 wherein said display means includes a pair of opposing illuminating arrows that individually illuminate when manual variation of the dial means in the direction indicated by the illuminated arrow is required to locate a null position.

8. The portable blood glucose monitoring meter of claim 7 wherein said illuminating means includes a pair of opposing illuminating arrows that illuminate simultaneously when a null position has been located.

9. The portable blood glucose monitoring meter of claim 1 further comprising at least one light emitting diode with temperature compensation means to achieve constant light emitting diode brightness as temperature varies in the absence of a microprocessor.

10. In a portable reflectance meter having an analog circuit with a potentiometer, the meter providing a measurement of color variances resulting from test solutions deposited on disposable chemically treated test strips to determine chemical concentrations of certain chemicals contained in the test solutions, the improvements comprising:

dial means for manually varying the resistance of said potentiometer to locate a null position that balances color changes of the disposable test strips against a reference;

calibration means integral with said dial means to receive replaceable, pre-printed, man-readable chemical concentration disks that correspond with the null position located by said dial means and that are empirically calibrated to correspond with the chemical characteristics of a particular batch of the disposable test strips used in the meter;

a light emitting diode for illuminating the chemically treated test strips;

first circuit means connected to said light emitting diode for providing a current signal to said light emitting diode, said current signal varying in accordance with variations in ambient temperature to maintain a constant intensity brightness signal from said light emitting diode; and

null prompting means for indicating to the user the manual variation of said dial means required to achieve a null position.

11. The meter of claim 10 wherein said first circuit means includes means for detecting a change in ambient temperature and producing a temperature signal in response thereto, and amplifier means responsive to said temperature signal for producing said current signal in accordance with said temperature signal.

12. The meter of claim 11 wherein said means for detecting a change in ambient temperature is a diode.

13. The meter of claim 12 wherein said amplifier means includes an operational amplifier and wherein said diode is forward biased with the cathode of said diode connected to an input of said operational amplifier, said amplifier means further including a transistor, said transistor connected in a feedback loop with said operational amplifier with the base of said transistor connected to the output of said operational amplifier, and wherein said transistor produces said current signal.

14. A device for providing a constant brightness light signal comprising:

temperature compensation means for producing a temperature signal wherein said temperature compensation means is a diode and said temperature signal is the forward voltage drop across said diode;

power source means responsive to said temperature signal for producing a power signal in accordance with said temperature signal wherein said power source means includes an operational amplifier and a transistor wherein the diode is forward biased with the cathode of the diode connected to an input of the operational amplifier, wherein said transistor is connected in a feedback loop with said operational amplifier with the base of the transistor connected to the output of said operational amplifier, and wherein the transistor produces the power signal; and

a light emitting diode responsive to said power signal and producing a constant intensity light signal in response thereto.