Method for making gas sensing element

• US 5,175,016 A
• Filed: 03/20/1990
• Issued: 12/29/1992
• Est. Priority Date: 03/20/1990
• Status: Expired due to Term

• Current Assignee: Terumo Cardiovascular Systems Corporation (Terumo Corporation)
• Original Assignee: 3M Company
• Inventors: Maxwell, Thomas P., Hacker, Thomas G., Holody, Mark Z., Yafuso, Masao
• Primary Examiner(s): Warden, Robert J.
• Assistant Examiner(s): Trembley, T. A.
• Application Number:
  US07/496,560
• Time in Patent Office: 1,015 Days
• Field of Search: 422/58, 422/68.1, 422/82.07, 422/82.06, 422/82.08, 422/82.09, 436/68, 436/163, 436/165, 436/172, 128/634, 350/96.29, 350/96.30, 350/96.33, 356/39, 250/227.14, 427/2, 427/389.7, 427/407.2
• US Class Current: 427/2.12
• CPC Class Codes: G01N 21/783 for analysing gases
• CPC Class Codes: G01N 31/223 for investigating presence of specific gases or aerosols G01N31/221, G01N31/222 take precedence; actuation of fire alarm by presence of smoke or gases G08B17/10
• CPC Class Codes: Y10T 436/204998 Inorganic carbon compounds

Abstract

A method for making a sensing element, and an assembled sensing element, useful in sensing the concentration of a gas, e.g., carbon dioxide, in a medium, e. g. blood, are disclosed. In one embodiment, the method comprises placing a quantity of a sensing composition precursor between and in contact with a transparent, gas impermeable solid disc and an opaque, gas permeable film, the sensing composition precursor comprises a sensing component, a polymer precursor and a cross-linking agent; and forming a gas sensing composition from this quantity of sensing composition precursor.

Claims

1. A method for making a gas sensing element useful in sensing the concentration of a gas in a medium comprising:

placing sensing composition precursor between and in contact with a transparent, gas impermeable solid disc and an opaque, gas permeable film oppositely disposed from said transparent, gas impermeable solid disc, said sensing composition precursor comprising a sensing component and a polymer precursor; and

, thereafter,

forming from said sensing composition precursor sensing composition including gas permeable and light permeable polymeric material and said sensing component, said forming including reacting said polymer precursor.

2. The method of claim 1 wherein said transparent, gas impermeable solid disc is made of glass, and said opaque, gas permeable film includes an opaque agent and a polymer selected from the group consisting of polyfluorohydrocarbons, polyfluorocarbons and mixtures thereof.

3. The method of claim 2 wherein said polymer is polytetrafluoroethylene.

4. The method of claim 1 wherein said sensing composition precursor further includes a cross-linking agent and said gas permeable and light permeable polymeric material is cross-linked.

5. The method of claim 1 wherein said sensing component is dissolved in an aqueous liquid dispersed in said gas permeable and light permeable polymeric material.

6. The method of claim 5 wherein said gas permeable and light permeable polymeric material is substantially ion impermeable, said dispersed aqueous liquid of said sensing composition is buffered and said sensing component is effective to provide a signal which varies as the pH of said dispersed aqueous liquid of said sensing composition varies.

7. The method of claim 6 wherein said dispersed aqueous liquid of said sensing composition has a pH in the range of about 6 to about 8 and the gas sensing element is effective in sensing the concentration of carbon dioxide in blood.

8. The method of claim 5 wherein said sensing composition precursor further includes a hydrophilic dispersing agent in an amount effective to facilitate maintaining said dispersed aqueous liquid in a dispersed state in said sensing composition precursor.

9. The method of claim 8 wherein said hydrophilic dispersing agent is selected from the group consisting of hydroxyalkyl celluloses and mixtures thereof.

10. The method of claim 8 wherein said hydrophilic dispersing agent is hydroxyethyl cellulose.

11. The method of claim 1 wherein said sensing composition is effective in sensing the concentration of oxygen in blood.

12. The method of claim 1 wherein said transparent, gas permeable solid disc has a thickness across two substantially opposing ends only one of which is in contact with said sensing composition precursor in the range of about 0.005 inches to about 0.1 inches.

13. A method for making a plurality of gas sensing elements useful in sensing the concentration of a gas in a medium comprising:

placing sensing composition precursor in contact with an opaque, gas permeable film, said sensing composition precursor comprising a sensing component and a polymer precursor;

placing a plurality of transparent, gas impermeable solid discs in contact with said sensing composition precursor;

thereafter,

forming from said sensing composition precursor sensing composition including gas permeable and light permeable polymeric material and said sensing component, said forming including reacting said polymer precursor; and

forming individual gas sensing elements each of which includes one of said transparent, gas impermeable solid discs, a portion of said sensing composition and a portion of said film.

14. The method of claim 13 wherein said transparent, gas impermeable solid discs are made of glass, and said opaque, gas permeable film includes an opaque agent and a polymer selected from the group consisting of polyfluorohydrocarbons, polyfluorocarbons and mixtures thereof.

15. The method of claim 14 wherein said polymer is polytetrafluoroethylene.

16. The method of claim 13 wherein said sensing composition precursor further includes a cross-linking agent and said gas permeable and light permeable polymeric material is cross-linked.

17. The method of claim 13 wherein each of said plurality of transparent, gas permeable solid discs has a thickness across two substantially opposing ends only one of which is in contact with said sensing composition precursor in the range of about 0.005 inches to about 0.1 inches.

18. A method for making a sensor useful in sensing the concentration of a gas in a medium comprising:

placing sensing composition precursor between and in contact with a transparent, gas impermeable solid disc and an opaque, gas permeable film, said sensing composition precursor comprising a sensing component and a polymer precursor;

thereafter

forming from said sensing composition precursor sensing composition including gas permeable and light permeable polymeric material and said sensing component, said forming including reacting said polymer precursor, the combination comprising said sensing composition, said transparent, gas impermeable solid disc and said opaque, gas permeable film being referred to as a sensing element; and

placing said sensing element at least partially in a cavity having an open end and being located in a substantially transparent sensor holder so that said opaque, gas permeable film is exposed to the medium.

19. The method of claim 18 which further comprises testing said sensing element for efficacy in sensing the concentration of a gas in a medium prior to said sensing element placing step.

20. The method of claim 18 which further comprises securing said sensing element to said substantially transparent sensor holder.

21. The method of claim 18 wherein said sensing component is dissolved in an aqueous liquid dispersed in said gas permeable and light permeable polymeric material.

22. The method of claim 21 wherein said gas permeable and light permeable polymeric material is substantially ion impermeable, said dispersed aqueous liquid of said sensing composition is buffered and said sensing component is effective to provide a signal which varies as the pH of said dispersed aqueous liquid of said sensing composition varies.

23. The method of claim 22 wherein said dispersed aqueous liquid of said sensing composition has a pH in the range of about 6 to about 8 and the gas sensing element is effective in sensing the concentration of carbon dioxide in blood.

24. The method of claim 18 wherein the gas sensing element is effective in sensing the concentration of oxygen in blood.

25. The method of claim 18 wherein said solid disc has a thickness across two substantially opposing ends only one of which is in contact with said sensing composition precursor in the range of about 0.005 inches to about 0.1 inches.