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Animal model for benign prostatic disease

  • US 5,175,383 A
  • Filed: 02/17/1989
  • Issued: 12/29/1992
  • Est. Priority Date: 02/17/1989
  • Status: Expired due to Term
First Claim
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1. A male transgenic mouse, whose germ cells and somatic cells contain an int-2 gene which is operably linked to a promoter effective for the expression of said gene in the urogenital tissues of said mouse and effective for the promotion of benign prostatic hyperplasia or hypertrophy in said mouse, said gene being introduced into said mouse, or an ancestor of said mouse, at an embryonic stage.

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