Implantable drug infusion reservoir having fluid impelling resilient foam member

• US 5,176,641 A
• Filed: 07/08/1991
• Issued: 01/05/1993
• Est. Priority Date: 07/08/1991
• Status: Expired due to Term

• Current Assignee: Arrow Interventional, Inc. (Teleflex Incorporated)
• Original Assignee: InfusAID, Inc. (Pfizer Inc.)
• Inventors: Idriss, Samir F.
• Primary Examiner(s): Wilson, John J.
• Assistant Examiner(s): Smith, Jeffrey A.
• Application Number:
  US07/726,659
• Time in Patent Office: 547 Days
• Field of Search: 604/133, 604/131, 604/892.1, 604/93
• US Class Current: 604/133
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/145 using pressurised reservoirs, e.g. pressurised by means of pistons

Abstract

An implantable infusion reservoir having a resilient foam member in a rigid housing to urge fluid to an implantation site. The foam member compresses upon charging and then expands to maintain a predetermined pressure characteristic within the fluid. The foam replaces the previously used two-phase propellent and eliminates the need for a hermetic metal bellows. The foam may be either closed celled or open celled, with or without a barrier skin. The device can be conformal to any desired shape and employ various metering techniques to deliver accurate quantities of fluid.

Claims

1. An implantable infusion system comprising:

a housing;

a reservoir in said housing;

an inlet in said housing for providing access to said reservoir from an external point for charging said reservoir with a fluid to be dispensed;

an outlet providing fluid communication between said reservoir and a remote location for dispensing said fluid;

means interposed between said reservoir and said outlet to meter the flow of said fluid; and

a solid compressible member filling substantially that portion of said reservoir unoccupied by said fluid for providing a force urging said fluid from said reservoir into said outlet by expansion and contracting upon filling said reservoir with fluid.

2. The implantable infusion system of claim 1, wherein said solid compressible member comprises a resilient foam.

3. The implantable infusion system of claim 2, wherein said resilient foam is a closed cell foam.

4. The implantable infusion system of claim 3, wherein said closed cell foam is coated with a solid coating.

5. The implantable infusion system of claim 1, wherein said housing conforms in shape to an implantation site in a body cavity.

6. The implantable infusion system of claim 1, wherein said inlet comprises a penetrable septum.

7. The implantable infusion system of claim 1, wherein said solid compressible member comprises an open cell foam having an impermeable cover thereon.

8. The implantable infusion system of claim 1, wherein said solid compressible member comprises an open cell foam having a separate impermeable cover, and a vent in said housing to expose said solid compressible member to ambient conditions.

9. The implantable infusion system of claim 1 further comprising a diaphragm to compress said solid compressible member in response to fluid pressure during filling.

10. An implantable infusion system comprising:

a hollow housing;

a penetrable septum mounted in said housing for providing access to an interior portion of said housing from an external point for supplying to said housing a fluid to be dispensed;

an outlet catheter establishing fluid communication between said interior portion of said housing and a location for dispensing said fluid; and

a resilient compressible member positioned in said housing and occupying the volume of said interior portion unoccupied by said fluid for providing a force by expansion pressurizing said fluid to expel said fluid from said interior portion into said outlet catheter, said resilient member contacting upon filling said interior portion with fluid.

11. The implantable infusion system of claim 10, wherein said resilient compressible member comprises a resilient foam.

12. The implantable infusion system of claim 11, wherein said resilient foam is a closed cell foam.

13. The implantable infusion system of claim 12 wherein said closed cell foam is coated with a solid coating.

14. The implantable infusion system of claim 10, wherein said resilient compressible member comprises an open cell foam having an impermeable cover thereon.

15. The implantable infusion system of claim 10 further comprising metering means interposed between said housing and said outlet catheter to meter fluid to said outlet catheter.

16. The implantable infusion system of claim 15, wherein said metering means comprises a restriction capillary.

17. The implantable infusion system of claim 15, wherein said metering means comprises an inlet valve, a pressurized volume accumulator and an outlet valve, said inlet and outlet valves operable to alternately fill and discharge said accumulator whereby a metered amount of fluid is delivered to said outlet catheter.

18. The implantable infusion system of claim 15, wherein said metering means comprises a peristaltic pump.

19. The implantable infusion system of claim 10, wherein said housing is shaped to be conformal with a body cavity that is the implantation site.