Flash sterilization with plasma
First Claim
1. A method for flash sterilization with plasma gases range comprisinga) exposing an unpackaged article in a sterilizing chamber to a gas plasma flowing from a plasma generating chamber until the temperature in the sterilizing chamber rises to a preselected maximum temperature of at least 100°
- C.;
b) terminating flow of the gas plasma to the sterilizing chamber until the temperature in the sterilizing chamber falls to a preselected temperature below the preselected maximum temperature; and
c) repeating steps (a) and (b) until sterilization of the article as defined by a preselected probability of survivors is effected.
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0 Petitions
Accused Products
Abstract
A method for flash sterilization with a plasma gas includes exposing an unpackaged article in a sterilizing chamber to a gas plasma flowing from a plasma generating chamber until the temperature in the sterilizing chamber rises to a preselected maximum temperature of at least 100° C. The flow of the plasma gas to the sterilizing chamber is terminated until the temperature in the sterilizing chamber falls to a temperature below the preselected maximum temperature. These steps are repeated until sterilization of the article is effected. The temperature below the preselected maximum temperature when gas plasma flow is again initiated is preferably not more than 3° C. below the preselected maximum temperature. The gas plasma can be generated from a mixture of gases consisting essentially of argon, helium, nitrogen or mixtures thereof; from 1 to 21 (v/v) % oxygen; and from 1 to 20 (v/v) % hydrogen; or a mixture containing from 1 to 10 (v/v) % oxygen and from 3 to 7 (v/v) % hydrogen; or a mixture containing 1 to 10 (v/v) % hydrogen and from 90 to 99 (v/v) % of argon, helium, nitrogen or mixtures thereof. Preferably the pressure in the sterilizing chamber rises to from 0.1 to 10 torr when the gas plasma is flowing into the chamber, and the pressure in the sterilizing chamber falls to a lower pressure when the gas plasma flow into the sterilizing chamber is terminated.
53 Citations
10 Claims
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1. A method for flash sterilization with plasma gases range comprising
a) exposing an unpackaged article in a sterilizing chamber to a gas plasma flowing from a plasma generating chamber until the temperature in the sterilizing chamber rises to a preselected maximum temperature of at least 100° - C.;
b) terminating flow of the gas plasma to the sterilizing chamber until the temperature in the sterilizing chamber falls to a preselected temperature below the preselected maximum temperature; and c) repeating steps (a) and (b) until sterilization of the article as defined by a preselected probability of survivors is effected. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
- C.;
Specification