Apparatus and method for measuring a bodily constituent
First Claim
1. An apparatus for measuring the concentration of a constituent in a bodily sample comprising:
- a test block adapted to receive said bodily sample and adapted to receive chemical reagent means reactive with the constituent desired to be measured, said test block producing an electrical output having a mathematical relation to the concentration of said constituent,a plurality of electrical gain devices operably connected to the test block to receive said test block electrical output,an analog-to-digital converter capable of accepting a maximum analog input, operably connected to the electrical output of said plurality of electrical gain devices, said electrical gain devices applying electrical gain to said test block output and said analog-to-digital converter selecting the largest device output which is less than the maximum acceptable analog input,memory means containing characterization information for said chemical reagent means and for said mathematical relation,a microprocessor operatively connected to the output of said analog-to-digital converter to receive the digital output of said converter and operatively connected to the memory means to read the contents of said memory means, said microprocessor adapted to calculate the concentration of said constituent, anda display means operably connected to said microprocessor to receive said calculated concentration of said constituent and display said concentration in human understandable form.
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Accused Products
Abstract
An apparatus and method for measuring a bodily constituent such as glucose or cholesterol by analyzing a sample taken from the body such as blood, saliva or urine. The sample is placed on a test strip inserted into the test block portion of the apparatus where the portion of the sample containing the constituent desired to be measured reacts with a chemical reagent. Products of this reaction have an absorbance/reflectance characteristic which is mathematically related to the concentration of the constituent in the bodily sample. The reflected light is absorbed by a photodiode and the output of the photodiode converted to a digital form where a microprocessor can calculate the concentration of the constituent using the mathematical relationship between the reflected light and concentration stored in memory means of the apparatus.
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Citations
33 Claims
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1. An apparatus for measuring the concentration of a constituent in a bodily sample comprising:
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a test block adapted to receive said bodily sample and adapted to receive chemical reagent means reactive with the constituent desired to be measured, said test block producing an electrical output having a mathematical relation to the concentration of said constituent, a plurality of electrical gain devices operably connected to the test block to receive said test block electrical output, an analog-to-digital converter capable of accepting a maximum analog input, operably connected to the electrical output of said plurality of electrical gain devices, said electrical gain devices applying electrical gain to said test block output and said analog-to-digital converter selecting the largest device output which is less than the maximum acceptable analog input, memory means containing characterization information for said chemical reagent means and for said mathematical relation, a microprocessor operatively connected to the output of said analog-to-digital converter to receive the digital output of said converter and operatively connected to the memory means to read the contents of said memory means, said microprocessor adapted to calculate the concentration of said constituent, and a display means operably connected to said microprocessor to receive said calculated concentration of said constituent and display said concentration in human understandable form. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. An apparatus for measuring the concentration of a constituent in a bodily sample comprising:
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a test block adapted to receive said bodily sample and adapted to receive chemical reagent means reactive with the constituent desired to be measured and producing an electrical output having a mathematical relation to the concentration of said constituent, said test block having a light emitting diode that radiates electromagnetic radiation onto said bodily sample reacted with said reagent means and a photodiode that receives electromagnetic radiation reflected from said constituent reacted with said reagent means, said light emitting diode operably connected to a current source, the current from said current source causing said light emitting diode to emit electromagnetic radiation, said current source operably connected to a current control means, said means regulating the electromagnetic output of said light emitting diode by providing a plurality of current source current values, said photodiode adapted to receive electromagnetic radiation emitted by said light emitting diode and reflected by said chemical reagent means reacted with said constituent, said photodiode producing said test block output having said mathematical relation to the concentration of said constituent, an analog-to-digital converter operably connected to said photodiode and producing a digital equivalent of said test block output, memory means containing characterization information for said chemical reagent means and for said mathematical relation, a microprocessor operatively connected to the out put of said analog-to-digital converter to receive the digital output of said converter and operatively connected to the memory means to selectively read the contents of said memory means, said microprocessor adapted to calculate the concentration of said constituent, and a display means operably connected to said microprocessor to receive said calculated concentration of said constituent and display said concentration in human understandable form. - View Dependent Claims (10, 11, 12, 13, 14, 15)
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16. A apparatus for self-testing to determine the concentration of cholesterol comprising:
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a test block adapted to receive a bodily sample containing cholesterol and adapted to receive chemical reagent means reactive with cholesterol, means for entering into said apparatus a characterization value associated with said reactive chemical reagent means, an emitter and a receiver which comprise a portion of said test block, the output of said emitter impinging on the reagent means reacted with cholesterol and said receiver receiving a portion of the output after the output has interacted with the reagent means reacted with cholesterol, means for isolating said bodily sample, said reagent means and said receiver contained within said test block from extraneous environmental noise and contaminants, a microprocessor electrically connected to said receiver and in communication with the characterization value entered into said apparatus, adapted to calculate the concentration of cholesterol in the bodily sample deposited in the apparatus, and a display for presenting said calculated concentration of cholesterol in a human understandable form. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23, 24)
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25. A method for measuring the concentration of a constituent in a bodily sample comprising:
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taking said bodily sample and reacting said sample with a chemical reagent reactive with the constituent desired to be measured, producing an electrical output having a mathematical relation to the concentration of said constituent, producing a plurality of voltage values each of which is a multiple of the voltage associated with said electrical output of the test block, providing the plurality of voltages to an analog-to-digital converter, selecting for digital processing the largest voltage of the plurality which is less than or equal to the maximum input voltage of the analog-to-digital converter, providing the digital output of the analog-to-digital converter to a microprocessor which can address a memory means containing characterization information for said chemical reagent means, calculating in said microprocessor the concentration of said constituent from the digital form of the test block electrical output and the characterization information for said chemical reagent means, and displaying the calculated concentration of said constituent in human understandable form on a visible display output.
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26. A method for measuring the concentration of a bodily constituent comprising:
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storing in a memory device characterization information defining a mathematical relationship between the concentration of said constituent and electromagnetic radiation reflected by a chemical reagent means reacted with said constituent, receiving in a test block a bodily sample and said chemical reagent means reactive with the constituent desired to be measured in the bodily sample, producing electromagnetic radiation and directing it to impinge upon said constituent reacted with said reagent means, measuring electromagnetic radiation reflected from said sample reacted with said reagent means, producing an analog electrical output from said electromagnetic radiation reflected from said constituent reacted with said reagent means, said analog electrical output having said mathematical relationship to the concentration of said constituent, converting said analog electrical output to a digital equivalent, controlling the amount of electromagnetic radiation impinging upon said constituent reacted with said reagent means by controlling the power provided to the source of said electromagnetic radiation to produce an analog electrical output within a predetermined range, electronically calculating the concentration of said constituent by using the mathematical relation of the digital equivalent of the electrical output of the test block to the concentration of said constituent, and displaying said calculated concentration of constituent in human understandable form. - View Dependent Claims (27)
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28. An apparatus for measuring the concentration of a bodily constituent comprising:
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a test block adapted to receive a bodily sample and adapted to receive a chemical reagent strip reactive with the constituent desired to be measured and producing an electrical output having a mathematical relation to the concentration of said constituent, said test block having an emitter that radiates electromagnetic radiation onto said constituent reacted with said reagent strip and a receiver that receives electromagnetic radiation reflected from said constituent reacted with said reagent strip, said test block having separate, non-intersecting passages in said test block, a first passage containing the emitter and terminating at said chemical reagent strip and a second passage containing the receiver and terminating at said chemical reagent strip, said passages forming substantially different angles with respect to the surface of the chemical reagent strip, said test block further having a chamber with a plurality of surfaces, said surfaces disposed at individual angles to said chemical reagent strip such that electromagnetic radiation from said emitter passing through said chemical reagent strip is reflected substantially away from said chemical reagent strip, said emitter operably connected to a current source, the current from said current source causing said emitter to emit electromagnetic radiation, said receiver adapted to receive electromagnetic radiation emitted by said emitter and reflected by said chemical reagent strip reacted with said constituent, said receiver producing said test block output having said mathematical relation to the concentration of said constituent, an analog-to-digital converter operably connected to said receiver and producing a digital equivalent of said test block output, memory means containing said mathematical relation, a microprocessor operatively connected to the output of said analog-to-digital converter to receive the digital output of said converter and operatively connected to the memory means to selectively read the contents of said memory means, said microprocessor adapted to calculate the concentration of said constituent, and a display means operably connected to said microprocessor to receive said calculated concentration of said constituent and display said concentration in human understandable form. - View Dependent Claims (29, 30, 31, 32, 33)
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Specification