Anastomotic device

• US 5,180,392 A
• Filed: 11/15/1990
• Issued: 01/19/1993
• Est. Priority Date: 02/01/1988
• Status: Expired due to Fees

• Current Assignee: Daniel Bar-Shalom, Einar Skeie
• Original Assignee: Daniel Bar-Shalom, Einar Skeie
• Inventors: Skeie, Einar, Bar-Shalom, Daniel
• Primary Examiner(s): ISABELLA, DAVID J
• Application Number:
  US07/614,690
• Time in Patent Office: 796 Days
• Field of Search: 623/11, 623/12, 606/153, 606/155, 606/156
• US Class Current: 623/23.64
• CPC Class Codes: A61B 17/1114 of the digestive tract, e.g. bowels or oesophagus
• CPC Class Codes: A61L 31/06 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds A61L31/041 takes precedence
• CPC Class Codes: A61L 31/148 Materials at least partially resorbable by the body
• CPC Class Codes: C08L 71/02 Polyalkylene oxides

Abstract

A prosthesis for use in joining hollow, e.g. tubular, organ parts or systems, said prosthesis comprising a fragmentable body defining outer organ-supporting surface parts thereon adapted to be arranged in abutting relationship with inner surface parts of the organs to be joined, said body having a compressive strength sufficiently low to allow fragmentation of the body by application of a pressure to the outer surface of the tubular organs subsequently to the joining of the same, said pressure being below a pressure causing any substantial lesion of the tissue of the tubular organ parts. The material of the prosthesis is preferably one or more degradable and/or erodable and/or water-soluble, essentially non-toxic materials which are solid at a temperature of 40° C. or higher, in particular 60° C. or higher, the material preferably being a polyether, more preferably a polyglycol, in particular polyethylene glycol such as polyethylene glycol with an average molecular weight of from 10,000 to 35,000, especially about 20,000.

As shown in FIG. 3, the prosthesis (1) may have tapered outer ends (3) as well as an intermediary portion (4) between the organ-supporting parts and having a smaller diameter. In another embodiment as shown in FIG. 9 or FIG. 13, the end portions may consist of longitudinally and inwardly radially extending fins (11) to give the prosthesis tapering end portions. In a further embodiment, the prosthesis may be a section of tubing with ends cut at an oblique or right angle.

Claims

1. A prosthesis for use in joining hollow organ parts or systems, said prosthesis comprising a fragmentable body defining outer organ-supporting surface parts thereon adapted to be arranged in abutting relationship with inner surface parts of the organs to be joined;

said body having a compressive strength sufficiently low to allow fragmentation of the body by application of a pressure to the outer surface of the tubular organs subsequently to the anastomosing of the same, said pressure being below a pressure causing any substantial lesion of the tissue of the tubular organ parts and said compressive strength being in the range of from 20 to 100N.

2. A prosthesis according to claim 1 wherein said polyglycol material is polyethylene glycol which has an average molecular weight in the range of from 10,000 to 35,000.

3. A prosthesis according to claim 1 wherein said body has a substantially circular cross-section.

4. A prosthesis according to claim 1 wherein the ratio between the length and the largest diameter of the prosthesis is in the range form 2:

1 to 7;

1.

5. A prosthesis according to claim 1 wherein said body comprises end portions the supporting surface parts and a narrowed intermediate portion therebetween.

6. A prosthesis according to claim 1 wherein said body comprises end portions with tapered outer ends.

7. A prosthesis according to claim 1 wherein said body defines an inner cavity.

8. A prosthesis according to claim 7 having closed ends.

9. A prosthesis according to claim 7 having open ends.

10. A prosthesis according to claim 1, wherein said body is comprised of a degradable, non-toxic material that is solid at a temperature of at least 40°

C.

11. A method for joining hollow organ parts or system, said method comprisinginserting a prosthesis according to claim 1 into and between the organs to be joined;

2) joining the two organ parts by anastomosis; and

3) fragmenting the prosthesis by application of pressure to the outer surface of the tubular organs.

12. A prosthesis according to claim 11, wherein said material is solid at a temperature of at least 50°

C.

13. A prosthesis according to claim 11, wherein said material is solid at a temperature of at least 60°

C.

14. A prosthesis according to claim 2, wherein said polyethylene glycol has an average molecular weight in the range of from 15,000 to 30,000.

15. A prosthesis according to claim 1, wherein said compressive strength is in the range of from 30 to 80N.

16. A prosthesis according to claim 15, wherein said compressive strength is in the range of rom 40 to 70N.

17. A prosthesis according to claim 16, wherein said compressive strength is in the range of from 50 to 60N.

18. The method according to claim 11, wherein said pressure is less than the minimum pressure needed to cause any substantial lesion of the tissue of the tubular organ parts.

19. A prosthesis according to claim 1 which further comprises at least one thread-like fixation means having one end connected to the intermediate portion of the body for temporarily fixing the organ parts to the prosthesis.

20. A prosthesis according to claim 19, wherein said material is selected from the group consisting of hard paraffin, beeswax, ceresin, higher fatty alcohols, cholesterol, japan wax, kokkum butter, lard, microcrystalline wax, fractionated palm kernel oil, spermaceti, cetyl esters wax, squalene, wool alcohols, wool fat, carnauba wax, polyglycols, theobroma oil, chocolate, macrogol ethers, glycerol ethers, glycol ethers, and poloxamers.

21. A prosthesis according to claim 20, wherein said material is a polyglycol.

22. A prosthesis according to claim 14, wherein said polyethylene glycol has an average molecular weight of about 20,000.