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Time temperature indicator with distinct end point

  • US 5,182,212 A
  • Filed: 10/18/1991
  • Issued: 01/26/1993
  • Est. Priority Date: 01/31/1991
  • Status: Expired due to Fees
First Claim
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1. A method for making an indicator for indicating time-temperature histories in conjunction with the storage of sensitive products and compositions, comprising admixing a first specific reaction pair for generating acid, a second specific reaction pair for generating base and at least one pH sensitive dye to form an aqueous solution, said first specific reaction pair having a first substrate present in a stoichiometric excess amount over the amount of a specific substrate provide in said second specific reaction pair.

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