Film-coated sensor

• US 5,186,808 A
• Filed: 07/27/1990
• Issued: 02/16/1993
• Est. Priority Date: 01/29/1988
• Status: Expired due to Fees

• Current Assignee: Terumo Kabushiki Kaisha (Terumo Corporation)
• Original Assignee: Terumo Kabushiki Kaisha (Terumo Corporation)
• Inventors: Kasai, Satoru, Yamaguchi, Shuichiro, Uchida, Naoto, Shimomura, Takeshi, Oyama, Noboru
• Primary Examiner(s): Niebling, John
• Assistant Examiner(s): Bell, Bruce F.
• Application Number:
  US07/548,931
• Time in Patent Office: 935 Days
• Field of Search: 204/415, 204/418, 204/419, 204/403, 204/412, 204/424, 204/428, 204/426, 204/416
• US Class Current: 204/403.1
• CPC Class Codes: A61B 2562/02 Details of sensors specially adapted for in-vivo measurements
• CPC Class Codes: A61B 5/14542 for measuring blood gases A61B5/14551 takes precedence
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors

Abstract

A film-coated sensor is formed by providing an electrically conductive substrate (2), which has a sectional area of less than 10^-5 cm², connected to a lead wire (5) at one end of an insulative capillary (1) and inscribed in the capillary (1), and providing a coating film (7) at another end, which is open, of the capillary (1) by an electrolytic polymerization process.

The film-coated sensor obtained has a surface which is uniform, the film coating is easy to control, and since the sensor is not readily susceptible to flow of a specimen fluid, there is little drift and response is quick. Owing to its small size, the sensor is capable of measuring very small samples and of performing measurement upon being directly inserted into a living body or tissue.

The sensor can be used also as an enzyme sensor by coating the surface of the film-coated sensor with a fixing enzyme film.

Claims

1. A film-coated sensor comprising:

a capillary having two open ends;

an electrically conductive substrate having less than 10^-5 cm² cross-sectional area, being connected to a lead wire at one end and another end internally located at one open end of said capillary; and

a sensing film coating a surface of said another end of said electrically conductive substrate at said open end of said capillary for sensing a substance of interest contained in a biological fluid.

2. The film-coated sensor according to claim 1, wherein said electrically conductive substrate is at least one carbon fiber, a rod-shaped carbon, a gold wire or a metal oxide wire.

3. The film-coated sensor according to claim 1, wherein said sensing film comprises a reducing catalytic film for sensing a gas of interest and an enzyme film coating a surface of said reducing catalytic film for generating said gas of interest selectively in response to said substance of interest.