Sensor, apparatus and method for non-invasive measurement of oxygen saturation

• US 5,188,108 A
• Filed: 01/23/1991
• Issued: 02/23/1993
• Est. Priority Date: 02/15/1990
• Status: Expired due to Fees

• Current Assignee: Koninklijke Philips Electronics N.V. (Koninklijke Philips N.V.)
• Original Assignee: Hewlett-Packard Company (HP Inc.)
• Inventors: Secker, Herbert
• Primary Examiner(s): Howell, Kyle L.
• Assistant Examiner(s): NASSER, ROBERT L
• Application Number:
  US07/645,042
• Time in Patent Office: 762 Days
• Field of Search: 128/633, 128/664-666, 356/41, 250/341, 250/345
• US Class Current: 600/310
• CPC Class Codes: A61B 2562/0233 Special features of optical sensors or probes classified in A61B5/00
• CPC Class Codes: A61B 2562/0242 for varying or adjusting the optical path length in the tissue
• CPC Class Codes: A61B 2562/043 in a linear array
• CPC Class Codes: A61B 5/14542 for measuring blood gases A61B5/14551 takes precedence
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/1464 specially adapted for foetal tissue
• CPC Class Codes: A61B 5/252 by suction
• CPC Class Codes: A61B 5/4362 Assessing foetal parameters
• CPC Class Codes: A61B 5/6826 Finger
• CPC Class Codes: A61B 5/6838 Clamps or clips
• CPC Class Codes: A61B 5/7232 involving compression of the physiological signal, e.g. to extend the signal recording period
• CPC Class Codes: A61B 5/7246 using correlation, e.g. template matching or determination of similarity
• CPC Class Codes: G01N 21/49 within a body or fluid

Abstract

A sensor for non-invasive measurement of oxygen saturation using the reflection method comprises a red transmitter (55), an infrared transmitter (58) and a receiver (57). The distances between the transmitters and the receiver are selected such that the length of the light path (60, 61) between the red transmitter (55) and the receiver (57) is substantially equal to the length of the light path (62, 63) between the infrared transmitter (58) and the receiver (57). The sensor comprises a further red transmitter (56) which is used for another application at the human body or another tissue characteristics where the depth of penetration at the various wavelengths is different from the shown example. Together with an appropriate oximeter, manual or automatic adaptation is possible. Further signal improvement may be obtained by autocorrelating the received signal, detecting its frequency and cross-correlating it with a pattern function of the same frequency.

Claims

1. A sensor for noninvasive measurement of oxygen saturation by irradiating human tissue with electromagnetic waves and measuring the intensity of the reflected waves comprising:

(1.1) carrier means;

(1.2) at least two transmitter means for emitting electromagnetic waves of different wavelengths into the human tissue and mounted on said carrier means; and

(1.3) at least one receiver means disposed on said carrier means for receiving electromagnetic waves of said different wavelengths reflected from the human tissue, said at least two transmitters mounted on said carrier means at distances from said receiver selected such that the lengths of the electromagnetic wave paths through the human tissue at both different wavelengths are substantially equal.

2. A sensor according to claim 1 wherein said carrier means is geometrically shaped for application to a specific part of the human body, and that the distances between the transmitter and the receiver are determined based on average values of tissue characteristics of said specific human body part, selected such that the electromagnetic wave paths at at least two different wavelengths, are substantially equal.

3. A sensor according to claim 2 for measuring oxygen saturation of a fetus prior to and during birth, wherein said carrier means is a cap comprising at least two transmitting light emitting diodes, emitting electromagnetic waves of different wavelengths, and at least one receiver responsive to said different wavelengths.

4. A sensor according to claim 3, wherein said cap is a suction cup comprising a suction tube connected with a suction source.

5. A sensor according to claim 2, wherein said carrier means if substantially closed on itself in cross-section for application to a finger of an adult person.

6. Apparatus for noninvasive measurement of oxygen saturation for connection to a sensor according to claim 2 further comprising conversion means for converting the intensity of the received electromagnetic waves into electrical signals;

processing means for calculating oxygen saturation from said electrical signals; and

plausibility checking means for comparing the received signals with predefined limits or predefined signals and for generating an alarm or a warning message upon a significant deviation.

7. Apparatus for noninvasive measurement of oxygen saturation for connection to a sensor, particularly according to claim 2, further comprising conversion means for converting the intensity of the received electromagnetic waves into electrical signals;

comparison means for comparing said electrical signals with sets of predefined signals representative of certain places of application at the human body or representative of certain tissue characteristics and for selecting the set having the most common characteristics with said electrical signals;

correction means for correcting said electrical signals in dependency of the selected set; and

processing means for the calculation of oxygen saturation from said corrected electrical signals.

8. Apparatus according to claim 7, wherein said sets of predefined signals contain attenuation values representative of certain places of application of electromagnetic waves to the human body or of certain human tissue.

9. Apparatus according to claim 7, wherein said sets of predefined signals contain values of the amplitude of the alternating component representative of certain places of application of electromagnetic waves to the human body or of certain human tissue.

10. Apparatus according to claim 7, wherein said sets of predefined signals contain signal shapes representative of certain places of application of electromagnetic waves to the human body or of certain human tissue.

11. A sensor according to claim 1, further comprising at least one first transmitter emitting electromagnetic waves of a first wavelength and at least two second transmitters emitting electromagnetic waves of a second wavelength, wherein said first and second transmitters are mounted on said carrier means at different distances to said at least one receiver such that the length of the electromagnetic wave path through the human tissue between said first transmitter and said receiver is for tissue with a certain predefined characteristics substantially equal to the length of the light path through the human tissue between the first of said second transmitters and said receiver whereas the length of the light path through the human tissue between said first transmitter and said receiver is for tissue with another certain predefined characteristic is substantially equal to the length of the light path through the human tissue between the second of said second transmitters and said receiver.

12. A sensor according to claim 11, wherein it comprises 2n first transmitters and 2n second transmitters arranged symmetrically with respect to the receiver, n being an integer number with n≧

1.

13. Sensor according to claim 11, wherein said carrier means are geometrically shaped for application to a specific part of the human body.

14. A sensor according to claim 13 for measuring oxygen saturation of a fetus prior to and during birth, wherein said carrier means is a cap comprising at least two first light emitting diode transmitters emitting electromagnetic waves of a certain first wavelength, and at least two second light emitting diode transmitters emitting electromagnetic waves of a certain second wavelength, and at least one receiver responsive to said different wavelengths.

15. Sensor according to claim 14, wherein said cap is a suction cup comprising a suction tube connected with a suction source.

16. Apparatus for noninvasive measurement of oxygen saturation for connection to a sensor, according to claim 11, further comprising:

conversion means for converting the intensity of the received electromagnetic waves into electrical signals;

processing means for the calculation of oxygen saturation from said electrical signals, selection input means for selecting the place of application on the human body; and

transmitter/receiver selection means responsive to said selection input means and operable to select certain transmitters depending on the place of application.

17. Apparatus according to claim 16, further comprising plausibility checking means for comparing the received signals with predefined limits or predefined signals representative of the selected place of application and for generating an alarm or a warning message upon a significant deviation.

18. Apparatus for noninvasive measurement of oxygen saturation for connection to a sensor, particularly according to claim 11 further comprising:

conversion means for converting the intensity of received electromagnetic waves into electrical signals;

processing means for the calculation of oxygen saturation from said electrical signals; and

application detection means set up to select sequentially certain transmitters to compare each of the specific electrical signals associated with a certain transmitter with sets of predefined signals representative of certain places of application on the human body or representative of certain tissue characteristics and to select those of said specific electrical signals having the most common characteristics with a certain of said sets, and selection means for selecting the transmitter associated with said specific electrical signals having the most common characteristics with a certain of said sets, for further measurement.

19. A sensor for noninvasive measurement of oxygen saturation by irradiating human tissue with electromagnetic waves and measuring the intensity of the reflected waves comprising:

(2.1) carrier means;

(2.2) at least one transmitter means emitting electromagnetic waves of different wavelengths into the human tissue and mounted on said carrier means,

(2.3) at least two receiver means disposed on said carrier means, each of the receivers being sensitive to at least one of said different wavelengths reflected from the human tissue, said at least two receivers mounted on said carrier means at distances from said transmitter selected such that the lengths of the electromagnetic wave paths through the human tissue, at both different wavelengths, are substantially equal.

20. A sensor according to claim 19 wherein said carrier means is geometrically shaped for application to a specific part of the human body, and that the distance between the transmitter and receiver are determined based on average values of tissue characteristics of said specific human body part selected such that the electromagnetic wave path at at least two different wavelengths, are substantially equal.

21. Sensor according to claim 20 for measuring oxygen saturation of a fetus prior to and during birth, wherein said carrier means is a cap comprising at least two transmitting light emitting diodes, emitting electromagnetic waves of different wavelengths, and at least one receiver responsive to said different wavelengths.

22. Sensor according to claim 21 wherein said cap is a suction cup comprising a suction tube connected with a suction source.

23. A sensor according to claim 20 wherein said carrier means is substantially closed on itself in cross-section for application to a finger of an adult person.

24. Apparatus for noninvasive measurement of oxygen saturation for connection to a sensor according to claim 20 further comprising conversion means for converting the intensity of the received electromagnetic waves into electrical signals;

processing means for the calculating of oxygen saturating from said electrical signals; and

plausibility checking means for comparing the received signals with predefined limits or predefined signals and for generating an alarm or a warning message upon a significant deviation.

25. Apparatus for noninvasive measurement of oxygen saturation for connection to a sensor, particularly according to claim 20 further comprising:

conversion means for converting the intensity of the received electromagnetic waves into electrical signals;

comparison means for comparing said electrical signals with sets of predefined signals representative of certain places of the application at the human body or representative of certain tissue characteristics and for selecting the set having the most common characteristics with said electrical signals;

correction means for correcting said electrical signals in dependency of the selected set; and

processing means for the calculation of oxygen saturation from said corrected electrical signals.

26. Apparatus according to claim 25 wherein said sets of predefined signals contain attenuation values representative of certain places of application of electromagnetic waves to the human body or of certain human tissue.

27. Apparatus according to claim 25 wherein said sets of predefined signals contain values of the amplitude of the alternating component representative of certain places of application of electromagnetic waves to the human body or of certain human tissue.

28. Apparatus according to claim 25 wherein said sets of predefined signals contain signal shapes representative of certain places of application of electromagnetic waves to the human body or of certain human tissue.

29. A sensor according to claim 19 further comprising at least one first receiver disposed to receive electromagnetic waves of a first wavelength and at least two second receivers disposed to receive electromagnetic waves of a second wavelength, wherein said first and second receivers are mounted on said carrier means at different distances from said at least one transmitter such that the length of the light path through the human tissue between said transmitter and said first receiver is for tissue with a certain predefined characteristics substantially equal to the length of the light path through the human tissue between said transmitter and the first of said second receivers, whereas the length of the light path through the human tissue between said transmitter and said first receiver is for tissue with another certain predefined characteristics substantially equal to the length of the light path through the human tissue between said transmitter and the second of said second receivers.

30. Sensor according to claim 29 wherein said carrier means are geometrically shaped for application to a specific part of the human body.

31. Sensor according to claim 30 for measuring oxygen saturation of a fetus prior to and during birth, wherein said carrier means is a cap comprising at least two first light emitting diode transmitters emitting electromagnetic waves of a certain first wavelength, and at least two second light emitting diode transmitters emitting electromagnetic waves of a certain second wavelength, and at least one receiver responsive to said different wavelengths.

32. A sensor according to claim 31 wherein said cap is a suction cup comprising a suction tube connected with a suction source.

33. Apparatus for noninvasive measurement of oxygen saturation for connection to a sensor, particularly according to claim 29 further comprising:

conversion means for converting the intensity of the received electromagnetic waves into electrical signals;

processing means for the calculation of oxygen saturation from said electrical signals, selection input means for selecting the place of application on the human body, and transmitter/receiver selection means responsive to said selection input means and operable to select certain receiver depending on the place of application.

34. Apparatus according to claim 33 further comprising plausibility checking means for comparing the received signals with predefined limits or predefined signals representative of the selected place of application and for generating an alarm or a warning message upon a significant deviation.

35. Apparatus for noninvasive measurement of oxygen saturation for connection to a sensor, particularly according to claim 29 further comprising:

conversion means for converting the intensity of received electromagnetic waves into electrical signals;

processing means for the calculation of oxygen saturation from said electrical signals; and

application detection means set up to select sequentially certain receivers to compare each of the specific electrical signals associated with a certain receiver with sets of predefined signals representative of certain places of application on the human body or representative of certain tissue characteristics and to select those of said specific electrical signals having the most common characteristics with a certain of said sets, and selection means set up to select the receivers associated with said specific electrical signals having the most common characteristics with a certain of said sets, for further measurement.

36. A sensor for noninvasive measurement of oxygen saturation by irradiating human tissue with electromagnetic waves and measuring the intensity of the reflected waves comprising:

carrier means;

transmitter means for emitting electromagnetic waves of different wavelengths into said human tissue and mounted on said carrier means; and

receiver means disposed on said carrier means for receiving electromagnetic waves of said different wavelengths reflected from said human tissue, said transmitter means and receiver means mounted on said carrier means at distances from each other such that the lengths of the electromagnetic wave paths through the human tissue at both said different wavelengths are substantially equal.