Multipart chromatography column connection
First Claim
1. A multipart chromatography column connection having a two-part screwed union anchored on a bead of a column body or on a thread of a metal column or its surrounding jacket, comprisingan upper part having a window in which a nut is arranged for free turning;
- a bushing having an external thread which meshes with the nut;
an adaptor screwed to a lower end of the bushing;
a capillary held in sealing compression between the adaptor and the bushing; and
a sealing insert screwed to the free end of the adaptor, wherein the adaptor and sealing insert have mutually-aligned bores which are connected to the capillary and which have sealing surfaces bearing against one another.
1 Assignment
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Accused Products
Abstract
A multipart chromatography column connection having a two-part screwed union anchored on the head of a column body or on the thread of a metal column or a surrounding jacket is disclosed. The connection has an upper part and a lower part, a bushing, fixed therein, with a capillary and a sealing insert of soft plastic at the end. The upper part of the screwed union has a window in which a nut is arranged for free turning. The bushing has an external thread which meshes with the nut. The nut and bushing are made of a hard material. An adaptor, also made of hard material, is screwed to the lower end of the bushing, the capillary being held in sealing compression between the adaptor and the bushing. The sealing insert is screwed to the free end of the adaptor and the adaptor and sealing insert have mutually aligned bores, which are connected to the capillary, and which have sealing surfaces bearing against one another. A method for filling a chromatography column is also disclosed, in which the column is filled with a suspension of packing material and the carrier fluid is expelled under pressure by a ram.
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Citations
10 Claims
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1. A multipart chromatography column connection having a two-part screwed union anchored on a bead of a column body or on a thread of a metal column or its surrounding jacket, comprising
an upper part having a window in which a nut is arranged for free turning; -
a bushing having an external thread which meshes with the nut; an adaptor screwed to a lower end of the bushing; a capillary held in sealing compression between the adaptor and the bushing; and a sealing insert screwed to the free end of the adaptor, wherein the adaptor and sealing insert have mutually-aligned bores which are connected to the capillary and which have sealing surfaces bearing against one another.
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- 2. A chromatography column connection according to claim I, wherein the bushing and the nut are made of a hard material.
Specification