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Receptor-based biosensors

  • US 5,192,507 A
  • Filed: 03/04/1991
  • Issued: 03/09/1993
  • Est. Priority Date: 06/05/1987
  • Status: Expired due to Term
First Claim
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1. An opiate receptor-containing biosensor for the determination of an opiate in a sample comprising:

  • a) a polymeric film formed by chemical copolymerization of a solution comprising;

    1) a base component which is a protein,2) an opiate receptor; and

    3) at least one stabilizer selected from the group consisting of lipids, detergents and antioxidants;

    b) a first sensor comprising a first conductor and a second conductor which are in contact with said film; and

    c) a current source in conductive contact with the first and second conductors for measuring an electrical characteristic of the polymeric film.

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