Method and apparatus for transcutaneous electrical cardiac pacing

• US 5,193,537 A
• Filed: 06/12/1990
• Issued: 03/16/1993
• Est. Priority Date: 06/12/1990
• Status: Expired due to Term

• Current Assignee: Zoll Medical Corporation (Asahi Kasei Corporation)
• Original Assignee: Zmd Corporation
• Inventors: Freeman, Gary A.
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): Getzow, Scott M.
• Application Number:
  US07/536,968
• Time in Patent Office: 1,008 Days
• Field of Search: 128/419 PG, 128/419 D, 128/421
• US Class Current: 607/10
• CPC Class Codes: A61N 1/3625 External stimulators

Abstract

Method and apparatus for transcutaneously pacing the heart with pacing stimuli each of which comprise a series of individual pulses. The heart reacts to the series of pulses as if the series were one continuous pulse, whereas the pulse series produces skeletal muscle reactions that are similar to that which would be expected for individual pulses. The result is reduced stimulation of skeletal muscles and nerves, and less discomfort for the patient. Further reduction in stimulation of skeletal muscles and nerves can be achieved by providing a series of subthreshold initial pulses in each pacing stimulus.

Claims

1. Apparatus for transcutaneously pacing a heart at a pacing rate, the apparatus comprising

stimuli generating circuitry for generating electrical stimuli at an output, and

electrodes connected to the output of the stimuli generating circuitry and adapted for delivering the electrical stimuli to a patient'"'"'s chest,

wherein said electrical stimuli include pacing stimuli delivered at the pacing rate, each pacing stimulus comprising a series of individual pulses,

wherein each series of pulses has a duration and amplitude making it capable, as a group, of causing a contraction of the heart, but each individual pulse has a duration and amplitude making it incapable, by itself, of causing such a contraction.

2. Apparatus for transcutaneously pacing a heart at a pacing rate, the apparatus comprising

stimuli generating circuitry for generating electrical stimuli at an output, and

electrodes connected to the output of the stimuli generating circuitry and adapted for delivering the electrical stimuli to a patient'"'"'s chest,

wherein said electrical stimuli include pacing stimuli delivered at the pacing rate, each pacing stimulus comprising a series of individual pulses,

wherein said series of pulses extends for a duration of at least 5 msec.

3. Apparatus for transcutaneously pacing a heart at a pacing rate, the apparatus comprising

stimuli generating circuitry for generating electrical stimuli at an output, and

electrodes connected to the output of the stimuli generating circuitry and adapted for delivering the electrical stimuli to a patients'"'"'s chest,

wherein said electrical stimuli include pacing stimuli delivered at the pacing rate, each pacing stimulus comprising a series of individual pulses,

wherein the duration of the individual pacing pulses averages less than 0.5 msec.

4. The apparatus of claim 3 wherein said average pulse duration is less than 250 microseconds.

5. The apparatus of claim 4 wherein said average pulse duration is less than 50 microseconds.

6. The apparatus of either of claims 3, 4, or 5 wherein the duty cycle of said individual pulses is greater than 20%.

7. The apparatus of claim 6 wherein the duty cycle of said individual pulses is greater than 50%.

8. The apparatus of claim 6 wherein the average amplitudes of said series of individual pacing pulses rise from a first amplitude to a second amplitude.

9. The apparatus of claim 8 wherein said first amplitude is less than the threshold for stimulation of skeletal muscle.

10. The apparatus of claim 9 wherein said second amplitude is reached in not less than 2 pulses.

11. Apparatus for transcutaneously pacing a heart at a pacing rate, the apparatus comprising

stimuli generating circuitry for generating electrical stimuli at an output, and

electrodes connected to the output of the stimuli generating circuitry and adapted for delivering the electrical stimuli to a patient'"'"'s chest,

wherein said electrical stimuli include pacing stimuli delivered at the pacing rate, each pacing stimulus comprising a series of individual pulses,

wherein the amplitude of said pacing stimulus in the interval between individual pulses is less than the threshold amplitude for stimulating cardiac muscle.

12. Apparatus for transcutaneously pacing a heart at a pacing rate, the apparatus comprising

stimuli generating circuitry for generating electrical stimuli at an output, and

electrodes connected to the output of the stimuli generating circuitry and adapted for delivering the electrical stimuli to a patient'"'"'s chest,

wherein said electrical stimuli include pacing stimuli delivered at the pacing rate, each pacing stimulus comprising a plurality of pulses, with at least the initial pulse in each stimulus having an amplitude less than the threshold for causing contractions of skeletal muscle and cardiac muscle, and subsequent pulses have amplitudes greater than said threshold.

13. The apparatus of claim 12 wherein each succeeding initial pulse has a generally greater amplitude than the preceding pulses.

14. Apparatus for transcutaneously pacing a heart at a pacing rate, the apparatus comprising

stimuli generating circuitry for generating electrical stimuli at an output, and

electrodes connected to the output of the stimuli generating circuitry and adapted for delivering the electrical stimuli to a patient'"'"'s chest,

wherein said electrical stimuli include pacing stimuli delivered at the pacing rate, each pacing stimulus comprising a series of individual pulses,

wherein the series of individual pulses is such that, at cardiac threshold (i.e., when the pacing stimuli are adjusted to an amplitude just high enough to cause cardiac contractions), there is less skeletal muscle stimulation than would result using a continuous pulse having the same duration as the series of pulses.

15. Apparatus for transcutaneously pacing a heart at a pacing rate, the apparatus comprising

stimuli generating circuitry for generating electrical stimuli at an output, and

electrodes connected to the output of the stimuli generating circuitry and adapted for delivering the electrical stimuli to a patient'"'"'chest,

wherein said electrical stimuli include pacing stimuli delivered at the pacing rate, each pacing stimulus comprising a series of individual pulses,

wherein the series of individual pulses is such that, at cardiac threshold (i.e., when the pacing stimuli are adjusted to an amplitude just high enough to cause cardiac contractions), there is less discomfort to the patient than would result using a continuous pulse having the same duration as the series of pulses.

16. A method of transcutaneously pacing a heart at a pacing rate, the method comprising the steps of:

generating electrical pacing stimuli;

delivering the stimuli to a patient through electrodes applied to the patient'"'"'s chest;

wherein the pacing stimuli generated and delivered to the patient comprise a series of individual pulses,

wherein each series of pulses has a duration and amplitude making it capable, as a group, of causing a contraction of the heart, but each individual pulse has a duration and amplitude making it incapable, by itself, of causing such a contraction.

17. A method of transcutaneously pacing a heart at a pacing rate, the method comprising the steps of:

generating electrical pacing stimuli;

delivering the stimuli to a patient through electrodes applied to the patient'"'"'s chest;

wherein the pacing stimuli generated and delivered to the patient comprise a series of individual pulses,

wherein said series of pulses extends for a duration of at least 5 msec.

18. A method of transcutaneously pacing a heart at a pacing rate, the method comprising the steps of:

generating electrical pacing stimuli;

delivering the stimuli to a patient through electrodes applied to the patient'"'"'s chest;

wherein the pacing stimuli generated and delivered to the patient comprise a series of individual pulses,

wherein the duration of the individual pacing pulses averages less than 0.5 msec.

19. The method of claim 18 wherein said average pulse duration is less than 250 microseconds.

20. The method of claim 19 wherein said average pulse duration is less than 50 microseconds.

21. The method of either of claim s 18, 19, or 20 wherein the duty cycle of said individual pulses is greater than 20%.

22. The method of claim 21 wherein the duty cycle of said individual pulses is greater than 50%.

23. The method of claim 21 wherein the average amplitudes of said series of individual pulses rise from a first amplitude to a second amplitude.

24. The method of claim 23 wherein said first amplitude is less than the threshold for stimulation of skeletal muscle.

25. The method of claim 24 wherein said second amplitude is reached in not less than 2 pulses.

26. A method of transcutaneously pacing a heart at a pacing rate, the method comprising the steps of:

generating electrical pacing stimuli;

delivering the stimuli to a patient through electrodes applied to the patient'"'"'s chest;

wherein the pacing stimuli generated and delivered to the patient comprise a series of individual pulses,

wherein the amplitude of said pacing stimulus in the interval between individual pulses is less than the pulse amplitude required for stimulating cardiac muscle if the pulse amplitude remained constant for the duration of the series of pulses.

27. A method of transcutaneously pacing a heart at a pacing rate, the method comprising the steps of:

generating electrical pacing stimuli;

delivering the stimuli to a patient through electrodes applied to the patient'"'"'s chest;

wherein the pacing stimuli generated and delivered to the patient comprise a plurality of pulses, with at least the initial pulse in each stimulus having an amplitude less than the threshold for causing contractions of skeletal muscle and cardiac muscle, and subsequent pulses have amplitudes greater than said threshold.

28. The method of claim 27 wherein each succeeding initial pulse has a generally greater amplitude than the preceding pulses.

29. A method of transcutaneously pacing a heart at a pacing rate, the method comprising the steps of:

generating electrical pacing stimuli;

delivering the stimuli to a patient through electrodes applied to the patient'"'"'s chest;

wherein the pacing stimuli generated and delivered to the patient comprise a series of individual pulses,

wherein the series of individual pulses is such that, at cardiac threshold (i.e. when the pacing stimuli are adjusted to an amplitude just high enough to cause cardiac contractions), there is less skeletal muscle stimulation than would result using a continuous pulse having the same duration as the series of pulses.

30. A method of transcutaneously pacing a heart at a pacing rate, the method comprising the steps of:

generating electrical pacing stimuli;

delivering the stimuli to a patient through electrodes applied to the patient'"'"'s chest;

wherein the pacing stimuli generated and delivered to the patient comprise a series of individual pulses,

wherein the series of individual pulses is such that, at cardiac threshold (i.e. when the pacing stimuli are adjusted to an amplitude just high enough to cause cardiac contractions), there is less discomfort to the patient than would result using a continuous pulse having the same duration as the series of pulses.