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Precisely regulated expression of deleterious genes

  • US 5,196,318 A
  • Filed: 06/26/1990
  • Issued: 03/23/1993
  • Est. Priority Date: 06/26/1990
  • Status: Expired due to Term
First Claim
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1. An expression system comprising a lux regulatory circuit, said regulatory circuit further comprising a luxR gene and truncated luxI gene of Vibrio, operably linked to and capable of stringently regulating expression of a gene, a product of which said gene is deleterious to an Escherichia coil host cell in which said expression system and said gene are resident.

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