Digoxigenin derivatives and use thereof
First Claim
1. Digoxigenin derivative of formula:
- ##STR9## wherein n is a whole number from 1 to 4, and Z is --CN, --COOC2 H5, ##STR10##
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Abstract
The present invention provides digoxigenin derivatives of the formula: ##STR1## wherein n is a whole number of from 1 to 4 and Z is a carboxyl group or a functional derivative derived therefrom. The present invention also provides digoxigenin conjugates of the general formula: ##STR2## wherein the carrier is an immunogenic carrier material, a nucleic acid or a labelled immunocomponent of a labelled digoxigenin immunoconjugate for use in an immunoassay, m is a number from 1 to the number of coupling positions available on the carrier and Y is the group formed by the reaction of the carboxyl function Z of the digoxigenin derivative of general formula (I) with the reacting position of the carrier material. Also described are uses of these conjugates as nucleic acid probes, immunogens, and in immunoassay.
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Citations
6 Claims
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1. Digoxigenin derivative of formula:
- ##STR9## wherein n is a whole number from 1 to 4, and Z is --CN, --COOC2 H5, ##STR10##
- View Dependent Claims (2)
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3. Digoxigenin conjugate of the formula:
- ##STR11## wherein said carrier is an immunogenic protein or polypeptide, a nucleic acid or a labelled immunocomponent of a labelled digoxigenin immunoconjugate, m is a whole number from 1 to the number of coupling positions available on said carrier, and Y is ##STR12##
- View Dependent Claims (4, 5, 6)
Specification