Subcutaneous implantable multiple-agent delivery system
First Claim
1. A subcutaneously implantably, multi-agent delivery system, comprising:
- (a) a pod for subcutaneous implantation beneath the dermis of the human body, said pod comprising a porous surface between an interior and exterior thereof and, further comprising, fluid transfer means in fluid communication with said porous surface, said pod having an opening at the top thereof, said pod formed of a bio-compatible material, said porous surface between said interior and exterior of said pod provided with one or more vascular growth factors to promote growth of blood capillaries into and about said porous surface of said pod;
(b) a dome portioned for complemental detachable securement within said opening of said pod, said dome including at least one chamber having selectable fluid communication with said fluid transfer means of said pod, in which bio-acting materials may be stored within said chamber of said dome prior to implantation, said dome formed of a biocompatible material, attached to said pod; and
(c) time dependent material release means interfaced between said chamber of said dome and said fluid transfer means of said pod,whereby said bio-acting materials are controllably released from said chamber of said dome, into said pod and, therefrom, through said porous surface into the bloodstream, in which said dome, after exhaustion of the materials therewithin, may be removed, refilled and re-secured to said pod.
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Accused Products
Abstract
There is provided an implantable multiple-agent delivery system which includes a pod proportioned for subcutaneous implantation beneath the dermis of the skin, the pod including a porous surface having at least one internal chamber there within which is in fluid communication with the porous surface. The system further includes a dome proportioned for complemental, selectable detachable securement upon the pod. The dome includes a plurality of interior chambers, each in fluid communication with the internal chambers of the pod. Bio-acting agents, such as hormones, biologic response modifiers, free radical scavengers, and other therapeutic agents may be provided, within the chambers of the dome, prior to implantation. Such agents with the chambers of the dome will, through the use of time release microelectronics, enter at least one of the interior chambers of the pod for transmission, through the porous surfaces thereof, into a growth factor stimulated capillary matrix and then to the bloodstream of the user. The pod may be removed, refilled, and resecured to the dome upon exhaustion of its contents or upon medical requirement for changes in medication. The surface of the pod may be treated with one or vascular growth factors or related biologic molecules.
57 Citations
5 Claims
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1. A subcutaneously implantably, multi-agent delivery system, comprising:
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(a) a pod for subcutaneous implantation beneath the dermis of the human body, said pod comprising a porous surface between an interior and exterior thereof and, further comprising, fluid transfer means in fluid communication with said porous surface, said pod having an opening at the top thereof, said pod formed of a bio-compatible material, said porous surface between said interior and exterior of said pod provided with one or more vascular growth factors to promote growth of blood capillaries into and about said porous surface of said pod; (b) a dome portioned for complemental detachable securement within said opening of said pod, said dome including at least one chamber having selectable fluid communication with said fluid transfer means of said pod, in which bio-acting materials may be stored within said chamber of said dome prior to implantation, said dome formed of a biocompatible material, attached to said pod; and (c) time dependent material release means interfaced between said chamber of said dome and said fluid transfer means of said pod, whereby said bio-acting materials are controllably released from said chamber of said dome, into said pod and, therefrom, through said porous surface into the bloodstream, in which said dome, after exhaustion of the materials therewithin, may be removed, refilled and re-secured to said pod. - View Dependent Claims (2, 3, 4, 5)
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Specification