Voice suppression of vagal stimulation

• US 5,205,285 A
• Filed: 06/14/1991
• Issued: 04/27/1993
• Est. Priority Date: 06/14/1991
• Status: Expired due to Term

• Current Assignee: LivaNova USA, Inc. (LivaNova Plc)
• Original Assignee: Cyberonics, Inc
• Inventors: Baker, Ross G. Jr.
• Primary Examiner(s): Howell, Kyle L.
• Assistant Examiner(s): Getzow, Scott M.
• Application Number:
  US07/715,428
• Time in Patent Office: 683 Days
• Field of Search: 128/419 R, 128/419 C, 128/420.5, 128/420.6, 128/423 R
• US Class Current: 607/45
• CPC Class Codes: A61N 1/36053 adapted for vagal stimulation A61N1/36114 takes precedence
• CPC Class Codes: A61N 1/36135 using physiological parameters

Abstract

In conjunction with a medical device for stimulating the vagus nerve of a patient to modulate the electrical activity thereof as part of a prescribed therapy, apparatus is provided to selectively suppress the stimulation while the patient is speaking, to avoid undesirable modulation of the voice. The suppression apparatus includes a speech sensor and discriminator, to detect speech by the patient while avoiding false detection attributable to sounds other than speech. The suppression of nerve stimulation is ceased after a preset time interval regardless of continued detection of speech, to assure that beneficial therapy is not unduly inhibited in favor of mere cosmetic considerations or in the presence of prolonged false detections. In the preferred embodiment, the discriminator selectively varies the sensitivity of the suppression apparatus to speech by the patient to enhance its selectivity over sounds attributable to other sources, such as by changing the value of a threshold level which must be crossed before the suppression of nerve stimulation can occur or continue, and by filtering out disturbances.

Claims

1. A medical device for stimulating the vagus nerve of a patient to modulate the electrical activity thereof as part of a prescribed therapy, comprising:

signal generating means for generating a predetermined signal to stimulate the vagus nerve, and

sensing means responsive to speech by the patient for automatically inhibiting said signal from stimulating the nerve.

2. The invention of claim 1, wherein

said sensing means includes means for detecting speech by the patient.

3. The invention of claim 2, wherein

said sensing means further includes means for removing the inhibition after a preset time interval regardless of continued detection of speech by the speech detecting means.

4. The invention of claim 2, wherein

said sensing means further includes means for discriminating speech by the patient from other sounds to avoid false detection of speech.

5. The invention of claim 2, wherein

said sensing means further includes for varying the sensitivity of the speech detecting means to speech by the patient, to reduce the likelihood of false detection of speech.

6. The invention of claim 5, wherein

said sensing means further includes means for removing the inhibition after a preset time interval regardless of continued detection of speech by the speech detecting means.

7. The invention of claim 5, wherein

the sensitivity varying means includes means for progressively decreasing the sensitivity of the speech detecting means to speech-generated phenomena, to discriminate against similar phenomena generated by sources other than speech.

8. The invention of claim 5, wherein

the sensing means further includes

means for setting a threshold value of the speech detecting means representing a predetermined sensitivity to patient speech, and

the sensitivity varying means includes

means for progressively increasing the threshold value of the speech detecting means to speech-generated phenomena, with increasing intervals of inhibition.

9. The invention of claim 4, wherein

the speech detecting means includes a vibration sensor.

10. The invention of claim 9, wherein

the vibration sensor includes transducer means for converting detected vibrations to an electrical signal, and

the speech discriminating means includes bandpass filter means for processing the electrical signal derived from the detected vibrations while substantially rejecting signal frequencies outside the voice frequency band.

11. The invention of claim 1, wherein

said sensing means includes means for removing the inhibition after a preset time interval regardless of continued detection of speech by the speech detecting means.

12. The invention of claim 1, wherein

the sensing means includes

means for summing the time intervals of inhibition of the signal generated by said signal generating means during a predetermined period, and

means for reducing the time intervals of subsequent inhibitions when the sum of the time intervals of inhibition during said predetermined period exceeds a present value.

13. In conjunction with a medical device for stimulating the vagus nerve of a patient to modulate the electrical activity of the nerve as part of a prescribed therapy, the improvement comprising:

sensing means responsive to speaking by the patient for automatically suppressing the nerve stimulation.

14. The improvement of claim 13, wherein

said sensing means includes means for restoring the capability of the device to further stimulate the vagus nerve after a preset time interval regardless of continued speaking by the patient.

15. The improvement of claim 14, wherein

said sensing means further includes means for distinguishing speaking by the patient from other phenomena to avoid false responses.

16. The improvement of claim 13, wherein

said sensing means includes means for disabling the suppression despite continued speech by the patient.

17. The improvement of claim 13, wherein

said sensing means includes means for varying the sensitivity of the device to speech by the patient, after a predetermined time interval in which stimulation is suppressed.

18. A method of avoiding undesirable modulation of the voice of a patient as a consequence of stimulation of the patient'"'"'s vagus nerve by a medical device to modulate the electrical activity of the nerve as part of a prescribed therapy, said method comprising:

sensing speech by the patient, and

responding to said sensing of speech by automatically suppressing the nerve stimulation.

19. The method of claim 18, further including

restoring the availability of stimulation after a preset time interval regardless of continued sensing of speech by the patient.

20. The method of claim 18, further including

distinguishing speech by the patient from other sounds to avoid suppression of stimulation in response to false detection of speech.