Reversibly immobilized biological materials in monolayer films on electrodes
First Claim
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1. A method for reversibly binding negatively charged biological particles in a liquid medium at neutral pH to an electrode surface, wherein said particles are selected from the group consisting of microbial cells and proteins the method comprising the steps of:
- (a) treating said electrode surface with an electrochemically active material selected from the group consisting of polyvinylferrocene, silicon-linked ferrocene and quinone;
(b) connecting said electrode to an electrical potential;
wherein said electrical potential induces a positive charge on said electrochemically active material; and
(c) exposing said medium to said electrode surface in a manner such that said charged particles are adsorbed on said electrode surface.
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Abstract
Methods and techniques are described for reversibly binding charged biological particles in a fluid medium to an electrode surface. The methods are useful in a variety of applications. The biological materials may include microbes, proteins, and viruses. The electrode surface may consist of reversibly electroactive materials such as polyvinylferrocene, silicon-linked ferrocene or quinone.
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7 Claims
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1. A method for reversibly binding negatively charged biological particles in a liquid medium at neutral pH to an electrode surface, wherein said particles are selected from the group consisting of microbial cells and proteins the method comprising the steps of:
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(a) treating said electrode surface with an electrochemically active material selected from the group consisting of polyvinylferrocene, silicon-linked ferrocene and quinone; (b) connecting said electrode to an electrical potential;
wherein said electrical potential induces a positive charge on said electrochemically active material; and(c) exposing said medium to said electrode surface in a manner such that said charged particles are adsorbed on said electrode surface. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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