Assembly for front face testing
First Claim
1. A holder assembly for a coverslip, said holder adapted for use in conjunction with a sample vessel and a device for assaying the light absorbing, reflecting or other optical characteristics of substances on such coverslip, anda holder body having spaced front and rear faces, and top and bottom ends, with said front face having a substantially planar portion, means located adjacent the bottom end of said front face for supporting a coverslip substantially flush with said planar portion, and a non-reflecting light sink;
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1 Assignment
0 Petitions
Accused Products
Abstract
A coverslip holder assembly for a front face fluorimetry flow cell has a holder body and a hingedly attached clamp for releasably maintaining a coverslip adjacent the front face of the holder body and flow cell. The assembly is preferably a unitary arrangement wherein the clamp is hingedly mounted adjacent the bottom end of the front face of the holder body, and has a convenient snap lock release mechanism at its top end to selectively lock the coverslip in flush arrangement with the front face. The holder assembly can provide a biased snug fit with a variety of cuvettes or similar sample vessels, and enables the use of highly colored or fluorescent compounds for perfusion in front face fluorimetry operations.
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Citations
20 Claims
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1. A holder assembly for a coverslip, said holder adapted for use in conjunction with a sample vessel and a device for assaying the light absorbing, reflecting or other optical characteristics of substances on such coverslip, and
a holder body having spaced front and rear faces, and top and bottom ends, with said front face having a substantially planar portion, means located adjacent the bottom end of said front face for supporting a coverslip substantially flush with said planar portion, and a non-reflecting light sink; - and
a clamp releasably attachable to said holder body, said clamp comprising means for maintaining a coverslip in substantially flush supported position relative to said front face of said holder body, and a light permeable portion generally aligned with said planar portion when in attached position with said holder body. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. An assembly for holding a coverslip upon which cells may be cultured for study within a sample vessel and device for assaying the light absorbing, reflecting or optical characteristics of such cells, said holder comprising:
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a holder body having spaced front and rear faces, top and bottom ends, and a nonreflecting light path between said front and rear surfaces, said front face having a substantially planar portion and means located adjacent the bottom end of said front face for supporting a coverslip substantially flush with said planar portion; and a clamp which is hingedly attached to said holder body, said clamp comprising means for maintaining a coverslip in substantially flush supported position relative to said front face of said holder body and a light permeable portion aligned with said light path when in attached position with said holder body, said clamp being rotatable away from said front face to facilitate coverslip loading, unloading and cleaning procedures. - View Dependent Claims (11, 12, 13, 14, 15, 16)
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17. An assembly for holding a coverslip upon which cells may be cultured for study within a cuvette and device for front face measurement of fluorescence of such cells, said holder comprising:
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a holder body having spaced front and rear faces, top and bottom ends, and a relatively hollow light path extending between said front and rear surfaces, said front face having a substantially planar portion and means located adjacent the bottom end of said front face for supporting a coverslip substantially flush with said planar portion; a clamp which is hingedly attached to said holder body, said clamp comprising a light permeable sight path substantially aligned with said light path when in attached position with said holder body; and means for selectively locking said clamp in attached position adjacent said front face of said holder body, wherein said coverslip is held in substantially flush supported position relative to said front face and aligned with said sight path. - View Dependent Claims (18, 19, 20)
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Specification