Therapeutic porous balloon catheter

• US 5,213,576 A
• Filed: 06/11/1991
• Issued: 05/25/1993
• Est. Priority Date: 06/11/1991
• Status: Expired due to Term

• Current Assignee: Cordis Corporation (Cardinal Health, Inc.)
• Original Assignee: Cordis Corporation (Cardinal Health, Inc.)
• Inventors: Abiuso, Christopher L., Leone, James E.
• Primary Examiner(s): Yasko, John D.
• Assistant Examiner(s): CERMAK, ADAM
• Application Number:
  US07/714,003
• Time in Patent Office: 714 Days
• Field of Search: 604/52, 604/53, 604/93, 604/96, 604/101-103, 604/264, 604/280, 604/265, 606/192, 606/191, 606/193, 606/194, 128/207.15
• US Class Current: 604/103.01
• CPC Class Codes: A61M 16/0443 Special cuff-wall materials A61M16/0481, A61M16/0422 take precedence
• CPC Class Codes: A61M 16/0456 one cuff within another
• CPC Class Codes: A61M 16/0481 through the cuff wall
• CPC Class Codes: A61M 2025/1013 with concentrically mounted balloons, e.g. being independently inflatable
• CPC Class Codes: A61M 2025/105 having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
• CPC Class Codes: A61M 25/104 used for angioplasty

Abstract

A balloon catheter comprises a catheter shaft, and first and second balloons carried on the catheter shaft with the second balloon positioned to at least partly overlie and sealingly enclose the first balloon. A lumen is defined by the catheter shaft to communicate between a space located within the first balloon and a proximal end portion of the catheter shaft. The first and second balloons each define holes of a size to permit medication delivered through the lumen to pass outwardly through the perforations of both the first and second balloons. By such an arrangement, medication may be directly delivered over a wide area to tissue without tissue damage.

Claims

1. A balloon catheter which comprises a catheter shaft, first and second balloons carried on said catheter shaft with said second balloon positioned to at least partly overlie and sealingly enclose said first balloon;

a lumen defined by said catheter shaft which communicates between a space located within said first balloon and a proximal end portion of said catheter shaft;

said first and second balloons defining holes of a size to permit medication delivered through said lumen to pass outwardly through the perforations of both the first and second balloons.

2. The catheter of claim 1 in which said second balloon completely encloses said first balloon.

3. The catheter of claim 2 in which said first and second balloons are tubular, one end of each of said first and second balloons defining a common, annular seal with said catheter shaft.

4. The catheter of claim 3 in which said first balloon is shorter than said second balloon, the ends of said balloons opposed to said one end each defining a separate, annular seal with said catheter shaft.

5. The catheter of claim 1 in which the holes of the first balloon are displaced out of registry with the holes of the second balloon.

6. The catheter of claim 5 in which the holes of the first balloon are circumferentially spaced from the holes of the second balloon.

7. The catheter of claim 6 in which the holes of the first balloon are longitudinally spaced from the perforations of the second balloon.

8. The catheter of claim 5 in which the perforations of the first balloon are longitudinally spaced from the perforations of the second balloon.

9. The catheter of claim 1 in which said catheter shaft defines a second lumen for receiving a guidewire.

12. The catheter of claim 1 in which at least one of said balloons comprises open-cell foam or expanded, fibrous plastic.

15. The catheter of claim 1 in which said second balloon expands to a diameter that is about 10 to 30 percent larger than the diameter of said first balloon.

16. The catheter of claim 1 in which the holes of said balloons are about 15 to 30 microns in diameter.

10. The catheter of claim in which a tubular, porous, liquid-permeable member is positioned between said first and second balloons.

11. The catheter of claim 10 in which said tubular, porous member is selected from the group consisting of open-cell foam, expanded, fibrous plastic, and a porous membrane.

13. The catheter of claim in which a tubular, porous, liquid permeable member is bonded to one of said first and second balloons in a position to extend across the perforations thereof.

14. The catheter of claim 13 in which said tubular, porous member comprises open-cell foam or expanded, fibrous plastic.

17. A balloon catheter which comprises a catheter shaft, first and second balloons carried on said catheter shaft with said second balloon positioned to sealingly enclose the first balloon;

a lumen defined by said catheter shaft which communicates between a space located within said first balloon and a proximal end portion of said catheter shaft;

said first and second balloons defining holes of a size to permit medication delivered through said lumen to pass outwardly through the holes of both the first and second balloons;

the holes of the first balloon being displaced out of registry with the holes of the second balloon.

18. The catheter of claim 17 in which the holes of the first balloon are circumferentially spaced from the holes of the second balloon.

19. The catheter of claim 18 in which the holes of the first balloon are longitudinally spaced from the holes of the second balloon.

20. The catheter of claim 17 in which said first and second balloons are tubular, one end of each of said first and second balloons defining a common annular seal with said catheter shaft, said first balloon being shorter than said second balloon, the ends of said balloons opposed to said one end each defining a separate, annular seal with said catheter shaft.

21. The catheter of claim 17 which defines a second lumen for receiving a guidewire.

22. A balloon catheter which comprises a catheter shaft, first and second balloons carried on said catheter shaft with said second balloon positioned to sealingly enclose said first balloon;

a lumen defined by said catheter shaft which communicates between a space located within said first balloon and a proximal end portion of said catheter shaft;

said first and second balloons defining holes of a size to permit medication delivered through said lumen to pass outwardly through the holes of both the first and second balloons, said first and second balloons and the space therebetween comprising at least one tubular, porous, liquid-permeable member made of open-cell foam or expanded, fibrous plastic.

23. The catheter of claim 22 in which at least one of said balloons comprises said open-cell foam or expanded, fibrous plastic tube.

24. The catheter of claim 22 in which said tubular, open-cell foam or expanded, fibrous plastic is carried between said first and second balloons.

25. The catheter of claim 22 in which said tubular, open-cell foam or expanded, fibrous plastic is bonded to one of said balloons.

26. A balloon catheter which comprises a catheter shaft and a balloon carried on said catheter shaft, a lumen defined by said catheter shaft which communicates between a space located within said balloon and a proximal end portion of said catheter shaft, said balloon comprising a plurality of holes of a size to permit medication delivered through said lumen to pass outwardly through said holes, said balloon carrying a tubular, microporous membrane covering said holes to break up streams of flowing medication the microporous membrane having pores that are smaller than the balloon holes.

27. The catheter of claim 26 in which said balloon defines a central, cylindrical portion and tapered end portions having minimum diameter ends adhered to the catheter shaft, said tubular microporous membrane being carried by the cylindrical portion of said balloon and spaced from the tapered end portions.

28. The catheter of claim 27 in which said tubular microporous membrane is made of polycarbonate resin.