Nerve condition monitoring system and electrode supporting structure

• US 5,215,100 A
• Filed: 04/29/1991
• Issued: 06/01/1993
• Est. Priority Date: 04/29/1991
• Status: Expired due to Fees

• Current Assignee: Healthsouth Occupational And Preventive Diagnostics Limited Partnership
• Original Assignee: Occupational Preventive Diagnostics, Inc.
• Inventors: Spitz, Lawrence K., Musser, Scott N., Jaeger, Scott
• Primary Examiner(s): Hindenburg, Max
• Assistant Examiner(s): Tucker, Guy V.
• Application Number:
  US07/692,930
• Time in Patent Office: 764 Days
• Field of Search: 128/741, 128/733, 128/734, 128/744, 128/774, 128/877, 128/878, 128/879, 128/639, 128/796, 128/89 R, 128/783, 128/736, 128/739, 128/800, 128/802, 128/755, 128/905 , 128/421, 128/420 A, 128/420.5, 374/142
• US Class Current: 600/554
• CPC Class Codes: A61B 5/05 Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves impedance plethysmography A61B5/0295; measuring movement of the entire body or parts thereof A61B5/11; detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof A61B5/24
• CPC Class Codes: A61B 5/4041 Evaluating nerves condition

Abstract

A portable system for substantially automated monitoring of nerve conduction velocity through the carpal tunnel of a patient includes an electrode supporting structure which supports stimulating and pickup electrodes in a predetermined spatial relationship so as to contact the patient'"'"'s arm and hand. The electrode supporting structure is a part of a housing which contains stimulating signal generating and response signal processing circuitry, which operates substantially automatically under control of a microprocessor. The microprocessor controls generation of stimulating pulses and determines the elapsed time until the occurrence of a predetermined response signal characteristic, such as its peak. Data relating to nerve conduction time or velocity measurements and response signal waveform are stored in a removable memory to permit later analysis and treatment recommendation by a physician. The system is useful for screening large groups of people at remote locations, such as workers at an employer'"'"'s facilities, for evaluating their median nerve condition and likelihood of developing carpal tunnel syndrome.

Claims

1. Patient nerve condition monitoring apparatus comprising:

a pair of stimulating electrodes adapted to apply an electrical stimulating signal to a patient;

a pair of pickup electrodes adapted to receive a response electrical signal from the patient induced by a stimulating signal; and

an electrode supporting structure supporting said stimulating electrodes in a location adapted to contact a portion of said patient'"'"'s arm adjacent the median nerve and supporting said pickup electrodes in a location adapted to contact a portion of the patient'"'"'s hand adjacent the median nerve when said stimulating electrodes are in contact with the patient'"'"'s arm, so that application of an electrical stimulating signal by said stimulating electrodes to the patient'"'"'s arm induces a sensory nerve conduction signal in the patient which is propagated along a median nerve conduction path extending from a location in the patient'"'"'s arm adjacent said stimulating electrodes to a location in the patient'"'"'s hand adjacent said pickup electrodes to produce a detectable sensory nerve response electrical signal at said pickup electrodes, and the length of the nerve conduction path is substantially permanently fixed by said electrode supporting structure.

2. Apparatus according to claim 1, wherein said electrode supporting structure includes surfaces which are shaped to locate the patient'"'"'s arm and hand with respect to said stimulating and pickup electrodes respectively.

3. Apparatus according to claim 2, wherein said electrode supporting structure includes a curved surface adapted to generally conform to a human forearm, and said stimulating electrodes are mounted to said curved surface.

4. Apparatus according to claim 1, wherein said electrode supporting structure includes a first surface adapted to receive a human forearm in contact with it and a second surface adjacent said first surface and adapted to receive a human hand in contact with it, said first surface being disposed at an angle between 90°

and 180°

with respect to said second surface so that movement of a patient'"'"'s forearm and hand when in contact with said first and second surfaces is inhibited.

5. Apparatus according to claim 1, further comprising a stimulating signal generator coupled to said stimulating electrodes and a response signal processor coupled to said pickup electrodes for processing response signals received by said pickup electrodes.

6. Apparatus according to claim 5, wherein said electrode supporting structure comprises a housing containing said stimulating signal generator and said response signal processor circuit.

7. Apparatus according to claim 1, wherein at least some of said electrodes are resiliently mounted to said electrode supporting structure.

8. Apparatus according to claim 1, further including a temperature sensor supported by said electrode supporting structure and adapted to contact said patient when said patient is in contact with said electrodes.

9. Patient nerve condition monitoring apparatus for monitoring nerve conduction through the carpal tunnel of a patient comprising:

a pair of stimulating electrodes adapted to be coupled to a patient'"'"'s arm;

a stimulating signal generator coupled to said stimulating electrodes;

a pair of pickup electrodes having a permanent predetermined spatial relationship to said stimulating electrodes, said pickup electrodes being adapted to be coupled to the patient'"'"'s hand so as to receive response signals generated in response to application of a stimulating signal to the patient'"'"'s arm; and

a response signal processor coupled to said pickup electrodes, said processor including means for determining the elapsed time between the application of a stimulating signal to said stimulating electrodes and the receipt of a predetermined response signal by said pickup electrodes.

10. Apparatus according to claim 9, wherein said processor includes a CPU, a memory coupled to said CPU for storing data and for storing operating programs to be executed by said CPU, and an analog-to-digital converter having at least one input for receiving analog signals and an output coupled to said CPU, said converter producing at its output digital signals which are related to analog signals received at said converter input.

11. Apparatus according to claim 10, wherein said stimulating signal generator includes a control input coupled to said CPU, and said CPU controls the generation of stimulating signals by said generator.

12. Apparatus according to claim 10, wherein said pickup electrodes are coupled to an input of said converter.

13. Apparatus according to claim 12, further comprising an amplifier having inputs coupled to said pickup electrodes and an output coupled to a converter input.

14. Apparatus according to claim 13, wherein said amplifier is a bandpass amplifier.

15. Apparatus according to claim 13, further including means for inhibiting the response of said amplifier to signals which are unrelated to nerve conduction signals.

16. Apparatus according to claim 15, wherein said amplifier response inhibiting means includes means for inhibiting the response of said amplifier to input signals occurring at predetermined times with respect to the time of generation of stimulating signals.

17. Apparatus according to claim 16, wherein said amplifier response inhibiting means includes a switch coupled to said amplifier, said switch having a control input coupled to said CPU.

18. Apparatus according to claim 10, wherein said memory includes removable static memory.

19. Apparatus according to claim 10, wherein said predetermined response signal is the peak value of the response signal received by said pickup electrodes.

20. Apparatus according to claim 10 wherein said CPU stores data in said memory relating to nerve conduction through the carpal tunnel of the patient.

21. Apparatus according to claim 20, wherein said stored data includes data relating to said elapsed time.

22. Apparatus according to claim 20, wherein said stored data includes data representing the response waveform received by said pickup electrodes in response to a stimulating signal applied to said stimulating electrodes.

23. Apparatus according to claim 20, wherein said apparatus includes .a temperature sensor coupled to said patient and producing an output related to the patient'"'"'s body temperature, and said stored data includes patient body temperature data.

24. Apparatus according to claim 20, wherein said CPU stores data in said memory relating to the patient being monitored.

25. Apparatus according to claim 20, wherein said CPU stores data in said memory relating to the apparatus being used in said patient monitoring.

26. Apparatus according to claim 10, wherein said processor includes one or more ports coupled to said CPU and one or more input/output devices coupled to said port(s).

27. Apparatus according to claim 26, wherein said input/output devices include a bar code reader.

28. Apparatus according to claim 26, wherein said input/output devices includes at least one alphanumeric display.

29. Apparatus according to claim 28 wherein said display displays information relating to patient nerve condition.

30. Apparatus according to claim 28, wherein said display displays information to prompt a user in proper use of the apparatus.

31. Apparatus according to claim 10, further including means for controlling the characteristics of stimulating signals produced by said stimulating signal generator.

32. Apparatus according to claim 31, wherein said signal characteristic controlling means is manually operable.

33. Apparatus according to claim 10, wherein said processor includes means for substantially automatically controlling said generation of stimulating signals and said determination of elapsed time.

34. Apparatus according to claim 33, further including a self-checking circuit for generating synthetic response signals and coupling synthetic response signals to said response signal processor.

35. Apparatus according to claim 33, wherein said control means includes means for determining the quality of contact between said patient and said electrodes.

36. Apparatus according to claim 35, wherein said contact quality determining means includes means for comparing a signal received at said pickup electrodes with a threshold signal value.

37. Apparatus according to claim 33, wherein said control means includes means for automatically and repeatedly generating stimulating electrical signals and monitoring response signals, and for terminating said generation and monitoring upon the occurrence of predetermined conditions.

38. Apparatus according to claim 37, wherein said predetermined conditions are conditions of response signals received by said pickup electrodes.

39. Apparatus according to claim 38, wherein said predetermined response signal conditions are the occurrence of a plurality of similar response signals in response to a plurality of successive stimulating signals.

40. Apparatus according to claim 39, wherein said response signals are similar in the time of occurrence of a predetermined response signal characteristic with respect to the time of the stimulating signal producing said response signal.

41. Apparatus according to claim 40, wherein said predetermined response signal characteristic is the peak amplitude of said response signal.

42. Apparatus according to claim 39, wherein said predetermined response signal conditions are the occurrence of similar response signals in response to about four successive stimulating signals.

43. A method of monitoring conduction velocity of nerves passing through the carpal tunnel of a patient comprising the steps of:

a. providing a pair of stimulating electrodes and a pair of pickup electrodes having a predetermined permanent spatial relationship to said stimulating electrodes;

b. coupling said pickup electrodes to the hand of the patient and coupling said stimulating electrodes to the forearm of the patient;

c. applying a stimulating electrical signal to said stimulating electrodes; and

d. determining the elapsed time between the application of a stimulating signal to the stimulating electrodes and the occurrence of a predetermined characteristic of the response signal produced at said response electrodes in response to said stimulating signal.

44. A method according to claim 43, wherein said coupling step b includes bringing the arm and hand of said patient into contact with an electrode supporting structure which supports said stimulating and pickup electrodes.

45. A method according to claim 44, further comprising the step of limiting the movement of the patient'"'"'s arm and hand with respect to said electrode supporting structure.

46. A method according to claim 43, further comprising the step of measuring the body temperature of said patient.

47. A method according to claim 43, further comprising the step of monitoring the quality of coupling between said patient and said electrodes.

48. A method according to claim 43, wherein steps c and d are performed automatically and repeatedly until the occurrence of a predetermined event.

49. A method according to claim 48, wherein said predetermined event is the determination of similar elapsed times in response to the application a plurality of stimulating signals.

50. A method according to claim 48, further comprising the step of storing data relating to said nerve conduction velocity monitoring.

51. A method according to claim 50, wherein said data storing step includes storage of data relating to said elapsed time.

52. A method according to claim 50, where said data storing step includes storing patient-identifying data.

53. A method according to claim 50 wherein said data storing step includes storing data relating to the circumstances under which said monitoring is performed.

54. A method according to claim 50, wherein said data storing step includes storing data representing a response signal waveform received at said response electrodes in response to said stimulating signal.