Apparatus for in vivo intracardial of a measured signal corresponding to the physical activity of a subject and a heart pacemaker having a stimulation rate controlled thereby

• US 5,218,961 A
• Filed: 09/17/1991
• Issued: 06/15/1993
• Est. Priority Date: 09/28/1990
• Status: Expired due to Term

• Current Assignee: Pacesetter AB (Abbott Laboratories)
• Original Assignee: Siemens AG
• Inventors: Lekholm, Anders
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US07/761,288
• Time in Patent Office: 637 Days
• Field of Search: 128/634, 128/670, 128/736, 128/419 PG
• US Class Current: 607/22
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61N 1/36585 controlled by two or more physical parameters

Abstract

An apparatus for the in vivo intracardial acquisition of a measured signal corresponding to the physical activity of a subject has an optoelectronic arrangement measuring the blood oxygen content of the subject and a temperature sensor for measuring the blood temperature. The apparatus can be operated so that a measured signal can be obtained which is optionally dependent on the blood oxygen content and the blood temperature, dependent only on the blood oxygen content, or dependent only on the blood temperature.

Claims

1. An apparatus for in vivo intracardial acquisition of a measured signal corresponding to the level of physical activity of a subject, said apparatus comprising:

first means for converting an electrical test signal into a first electrical signal component dependent on the blood oxygen content of said subject, the degree of dependence being dependent on the value of said test signal;

second means for converting said electrical test signal into a second electrical signal component dependent on the blood temperature of said subject, the degree of dependence being dependent on the value of said test signal;

said first means and said second means for converting being electrically combined in a circuit having only two terminals;

control circuitry coupled to said two terminals including drive circuit means for supplying said test signal to said first and second means for converting, and further including measuring means for generating a measured signal which includes said first and second signal components depending on blood oxygen content and blood temperature;

said test signal having a range of values including a first value below which said measured signal is significantly more dependent on blood temperature than on blood oxygen content and including a second value at which said measured signal is significantly more dependent on blood oxygen content than on blood temperature; and

means for adjusting said test signal to a value within said range including said first value and said second value.

2. An apparatus as claimed in claim 1 wherein said drive circuit means is a means for supplying an adjustable constant voltage to said two terminals and wherein said measuring means is a means for deriving said measured signal from current drawn by said first and second means.

3. An apparatus as claimed in claim 1 wherein said drive circuit means is a means for supplying an adjustable constant current to said first and second means and wherein said measuring means is a means for deriving said measured signal from a voltage drop between said two terminals.

4. An apparatus as claimed in claim 1 wherein said first means includes light transmitter means operated by said test signal for emitting light into the blood of said subject to an extent dependent on the value of said test signal and light receiver means for receiving light from said light transmitter means reflected from said blood, and wherein, when said test signal has a value at or less than said first value, substantially no light is emitted by said light transmitter means so that said signal component dependent of the blood oxygen content is substantially zero, and said measured signal is independent on blood oxygen content, and light is emitted by said light transmitter means when said test signal has a value greater than said first value so that said measured signal is also dependent on the blood oxygen content.

5. An apparatus as claimed in claim 1 wherein said first means includes a light emitting diode operated by said test signal, wherein said second means is a PTC resistor connected in series with said light emitting diode between said two terminals, wherein said first means further includes a phototransistor connected in parallel with said PTC resistor, and wherein said drive circuit means is a means for supplying an adjustable constant test current to said two terminals.

6. An apparatus as claimed in claim 1 wherein each of said light transmitter means and said light receiver means comprises a photoconductor element.

7. An apparatus as claimed in claim 1 wherein said temperature sensor means is a means having a resistance which is temperature-dependent.

8. An apparatus as claimed in claim 1 wherein said drive circuit means is a means for supplying a pulsed test signal of constant magnitude to said two terminals.

9. An apparatus as claimed in claim 1 further comprising:

means for controlling the stimulation rate of a heart pacemaker dependent on said measured signal.

10. An apparatus as claimed in claim 9 further comprising means for controlling said test signal of said drive circuit means dependent on the existing stimulation rate of said heart pacemaker.

11. An apparatus for in vivo intracardial acquisition of a measured signal corresponding to the level of physical activity of a subject, said apparatus comprising:

first means for converting an electrical test signal into a first electrical signal component dependent on the blood oxygen content of said subject, said first means having a temperature coefficient associated therewith;

second means for converting said electrical test signal into a second electrical signal component dependent on the blood temperature of said subject, said second means having a temperature coefficient associated therewith which is opposite in operational sign with respect to the temperature coefficient of said first means;

said first means and said second means being electrically combined in a circuit having only two terminals;

control circuitry coupled to said two terminals including drive circuit means for supplying said test signal to said first and second means, and further including measuring means for generating a measured signal which includes said signal first and second components depending on blood oxygen content and blood temperature;

said test signal having a range of values including a single value at which the temperature influences of said first and second means cancel each other so that said measured signal is dependent on blood oxygen only, with said measured signal also being dependent on blood temperature at all other values in said range; and

means for adjusting said test signal within said range including said single value.

12. An apparatus as claimed in claim 11 wherein said drive circuit means is a means for supplying an adjustable constant voltage to said two terminals and wherein said measuring means is a means for deriving said measured signal from current drawn by said first and second means.

13. An apparatus as claimed in claim 11 wherein said drive circuit means is a means for supplying an adjustable constant current to said first and second means and wherein said measuring means is a means for deriving said measured signal from a voltage drop between said two terminals.

14. An apparatus as claimed in claim 11 wherein said first means includes light transmitter means operated by said test signal for emitting light into the blood of said subject to an extent dependent on the value of said test signal and light receiver means for receiving light from said light transmitter means reflected from said blood, and wherein when said test signal has a value at or less than said first value substantially no light is emitted by said light transmitter means so that said signal component dependent on the blood oxygen content is substantially zero, and said measured signal is independent on blood oxygen content, and light is emitted by said light transmitter means when said test signal has a value greater than said first value so that said measured signal is also dependent on the blood oxygen content.

15. An apparatus as claimed in claim 11 wherein said first means includes a light emitting diode operated by said test signal, wherein said second means is a PTC resistor connected in series with said light emitting diode between said two terminals, wherein said first means further includes a phototransistor connected in parallel with said PTC resistor, and wherein said drive circuit means is a means for supplying an adjustable constant test current to said two terminals.

16. An apparatus as claimed in claim 11 wherein each of said light transmitter means and said light receiver means comprises a photoconductor element.

17. An apparatus as claimed in claim 11 wherein said temperature sensor means is a means having a resistance which is temperature-dependent.

18. An apparatus as claimed in claim 11 wherein said drive circuit means is a means for supplying a pulsed test signal of constant magnitude to said two terminals.

19. An apparatus as claimed in claim 11 further comprising:

pacing means for electrically stimulating a heart at a stimulation rate; and

means for controlling the stimulation rate of said pacing means dependent on said measured signal.

20. An apparatus as claimed in claim 11 further comprising means for controlling said test signal of said drive circuit means dependent on the existing stimulation rate of said pacing means.