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Peroxidase colloidal gold oxidase biosensors for mediatorless glucose determination

  • US 5,225,064 A
  • Filed: 03/06/1992
  • Issued: 07/06/1993
  • Est. Priority Date: 01/15/1992
  • Status: Expired due to Term
First Claim
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1. A bioelectrode comprising:

  • a conducting surface;

    a peroxidase adsorbed in a monolayer or close to a monolayer onto colloidal gold particles wherein the colloidal gold-adsorbed peroxidase is deposited on the conducting surface; and

    an oxidase layer atop the deposited colloidal gold adsorbed peroxidase wherein direct electron transfer to the conducting surface occurs in the presence of an analyte when the bioelectrode is suitably coupled with a reference/counter electrode.

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