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Alkylthio alkyl avermectins are active antiparasitic agents

  • US 5,229,415 A
  • Filed: 03/24/1992
  • Issued: 07/20/1993
  • Est. Priority Date: 03/24/1992
  • Status: Expired due to Term
First Claim
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1. A compound having the formula ##STR4## where:

  • n is 0;

    A is single or double bond;

    R1 is present only when A is a single bond and is H, OH, ═

    O, ═

    NOCH3 or halogen;

    R2 is C1 -C6 alkyl, C2 -C6 alkenyl, C3 -C8 cycloalkyl, C4 -C8 cycloalkenyl, phenyl, furyl or thienyl;

    R3 is OH or ═

    NOH;

    B is a single or double bond;

    R5 is present only when B is a single bond and is H, OH or halogen;

    R4 is ##STR5## and R6 is hydrogen or C1 -C3 alkyl.

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