Measuring apparatus

• US 5,231,576 A
• Filed: 09/07/1990
• Issued: 07/27/1993
• Est. Priority Date: 09/08/1989
• Status: Expired due to Fees

• Current Assignee: Terumo Kabushiki Kaisha
• Original Assignee: Terumo Kabushiki Kaisha, Yamatake-Honeywell Company Limited
• Inventors: Suzuki, Yoshiro, Kurihara, Noriyuki
• Primary Examiner(s): NOT, DEFINED
• Assistant Examiner(s): Tran, Khai
• Application Number:
  US07/578,577
• Time in Patent Office: 1,054 Days
• Field of Search: 364/497, 364/413.09, 364/413.02, 356/184, 128/677, 128/662.05, 128/664, 128/672
• US Class Current: 356/39
• CPC Class Codes: G01N 21/272 for following a reaction, e.g. for determining photometrically a reaction rate (photometric cinetic analysis)
• CPC Class Codes: G01N 21/78 producing a change of colour
• CPC Class Codes: G01N 21/8483 Investigating reagent band test-element handling not specific to a test method G01N33/4875; analytical elements specific to chemical analysis of biological material G01N33/52; autometer with reagent band G01N35/04
• CPC Class Codes: G01N 2201/1211 for temperature

Abstract

The present invention is an apparatus for measuring the constituent concentration of a specimen on the basis of the color change in a test material housed in a test piece, which has reacted because of the specimen. The apparatus irradiates the test material which is a test piece loaded in the apparatus'"'"'s main body and detects the intensity of the light reflected by the test material. A detection signal detected in the above way is sampled in a time period before and after the measurement timing at which the test material changes in color because of the specimen. An average value of the sampled detection signals is determined. The constituent concentration of the specimen is computed by referring to a stored conversion table on the basis of the average value determined in the above way.

Claims

1. A measuring apparatus adapted to receive a test piece, to which a specimen is applied, that measures a concentration of the specimen on the basis of a change of color of a test material which is housed in said test piece and which reacts with said specimen, comprising:

irradiation means for irradiating said test material with light;

loading detection means for detecting whether the test piece is inserted into a main body of the apparatus;

time measurement means for measuring a predetermined time period in which the reaction of said test material with the specimen is substantially completed, after the insertion of said test piece is detected by means of said loading detecting means;

detection means for detecting an intensity of the light reflected from said test material and outputting a corresponding analog signal;

digital conversion means for sampling said analog signal a plurality of times before and after the predetermined time period has elapsed and converting each sample into a digital signal; and

computation means for computing an average value of said digital signals sampled by said digital conversion means and determining the constituent concentration of said specimen by referring to a stored conversion table on the basis of said average value.

2. The measuring apparatus according to claim 1, further comprising temperature measurement means for measuring ambient temperature in which the apparatus is placed and correcting means for correcting said average value on the basis of said ambient temperature.

3. The measuring apparatus according to claim 1, further comprising display means for displaying the time measured by said time measurement means, by means of a count down on a display screen.

4. The measuring apparatus according to claim 1, further comprising storage means for storing the constituent concentration of said specimen together with the day and time of measurement;

and

selection means for automatically selecting whether or not said constituent concentration is stored in said storage means.

5. The measuring apparatus according to claim 1, further comprising temperature measurement means for measuring ambient temperature in which the apparatus is placed and correcting means for correcting said average value on the basis of said ambient temperature, and display means for displaying the time measured by said time measurement means, by means of a count down on a display screen.

6. The measuring apparatus according to claim 1, wherein said test piece is provided with a first opening on one side thereof and a second opening on another side thereof at a location opposite to said first opening, said first opening provided for applying the specimen to said test material therethrough, sand said second opening for irradiating said test material with the light and detecting the intensity of the reflected light therefrom.

11. The measuring apparatus according to claim 6, wherein said test material includes a liquid development layer in which said specimen is infiltrated through said first opening, a reagent layer which reacts with said specimen and a transparent layer between the reagent layer and the second opening, and said predetermined time period is defined by the time in which the coloring reaction between said specimen infiltrated through the liquid developing layer and said reagent layer is substantially completed.

7. A measuring apparatus adapted to receive a test piece, to which a specimen is applied, that measures a concentration of the specimen on the basis of a change of color of a test material which is housed in said test piece and which reacts with said specimen, comprising:

loading detection means for detecting whether the test piece is inserted into a main body of said apparatus;

time measurement means for measuring a predetermined time period in which the reaction of said test material with the specimen is substantially completed, after the insertion of said test piece is detected by means of said loading detection means;

irradiation means for irradiating said test material with light before and after the predetermined time period has elapsed;

detection means for detecting an intensity of light reflected from said test material irradiated by said irradiation means and outputting a corresponding analog signal;

digital conversion means for sampling said analog signal a plurality of times before and after said predetermined time period has elapsed and converting each sample into a digital signal;

computation means for computing an average measurement value by computing the average value of said digital signals sampled by said digital conversion means; and

arithmetic operation means for determining the constituent concentration of said specimen by referring to a stored conversion table on the basis of said average measurement value.

8. The measuring apparatus according to claim 7, further comprising temperature measurement means for measuring ambient temperature in which the apparatus is placed and correcting means for correcting said average value on the basis of said ambient temperature.

9. The measuring apparatus according to claim 7, further comprising display means which displays a lapse of the predetermined time period on a display screen at predetermined time intervals by means of counting down after the loading of said test piece is detected by means of said loading detection means.

10. The measuring apparatus according to claim 7, further comprising storage means for storing the constituent concentration of said specimen together with measurement day and time data;

and

selection means for automatically selecting whether or not said constituent concentration is stored in said storage means.

12. The measuring apparatus according to claim 7, further comprising temperature measurement means for measuring ambient temperature in which the apparatus is placed and correcting means for correcting said average value on the basis of said ambient temperature, and display means for displaying the time measured by said time measurement means, by means of a count down on a display screen.

13. The measuring apparatus according to claim 7, wherein said test piece is provided with a first opening on one side thereof and a second opening on another side thereof at a location opposite to said first opening, said first opening provided for applying the specimen to said test material therethrough, and said second opening for irradiating said test material with the light and detecting the intensity of the reflected light therefrom.

14. The measuring apparatus according to claim 13, wherein said test material includes a liquid development layer in which said specimen is infiltrated through said first opening, a reagent layer which reacts with said specimen and a transparent layer between the reagent layer and the second opening, and said predetermined time period is defined by the time in which the coloring reaction between said specimen infiltrated through the liquid developing layer and said reagent layer is substantially completed.