Additive device for vial

• US 5,232,029 A
• Filed: 09/25/1992
• Issued: 08/03/1993
• Est. Priority Date: 12/06/1990
• Status: Expired due to Fees

• Current Assignee: Abbott Laboratories
• Original Assignee: Abbott Laboratories
• Inventors: Knox, Kenneth H., Schlaupitz, Robert S.
• Primary Examiner(s): Cuchlinski, Jr., William A.
• Assistant Examiner(s): BENNETT, GEORGE B
• Application Number:
  US07/951,364
• Time in Patent Office: 312 Days
• Field of Search: 141/27, 141/97, 141/312, 141/329, 141/330, 141/369, 141/370, 141/371, 141/383, 141/384, 141/385, 141/386
• US Class Current: 141/329
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents

Abstract

An adapter has a cannula to deliver a drug to the interior of a vial. The vial contains a plunger that has a penetratable self-sealing rubber diaphragm, as is common. The adapter comprises a barrel adapted to fit over and telescope onto the vial, with a cannula rigidly mounted axially in the barrel and long enough to reach the bottom of the vial after penetrating the rubber diaphragm. The barrel incorporates fins that stabilize the cannula axially. Cover plugs are provided to close both the barrel and the vial before use. When the covers are removed and the barrel s fitted down over the vial, the cannula projects beyond the fins to penetrate the plunger and push the plunger to the bottom of the vial. The long barrel and the rigidly maintained cannula insure that the cannula cannot contact the inner wall of the vial.

Claims

1. An adapter for the transfer of liquid to an empty vial while maintaining the sterility of the liquid contact surface of the vial which comprises:

a barrel sleeve adapted to fit down over the vial,

the barrel sleeve having a closed upper end and an open lower end,

an elongated cannula extending from the closed end of the barrel sleeve toward the open end thereof whereby to penetrate a plunger in eh vial that is located adjacent the closed lower end of the vial and which has an axially pierceable central diaphragm,

the barrel sleeve being substantially the same length as the cannula in order to protect the cannula from engaging any contaminated parts of the equipment during its use,

the cannula being maintained substantially coaxially within the barrel sleeve.

2. The adapter of claim 1 wherein:

there are fins disposed about the cannula to maintain it in its axial position,

the fins extending along the cannula a sufficient distance to maintain the cannula in its axial position both before use and during use,

the cannula extending beyond the fins with a section adapted to penetrate the plunger.

3. The adapter of claim 1 with a cap adapted to close the open lower end of the sleeve before use, whereby to maintain its sterility, the cap being removable at the time of use.

4. The adapter of claim 1 wherein the cannula opens through a removable air filter in the closed upper end of the barrel sleeve to enable air to be expelled from below the pierceable plunger when the cannula is inserted therethrough.

5. The adapter of claim 1 wherein the vial has a side wall and the plunger is slidable therein with its pierceable diaphragm being penetratable by the cannula,

the barrel sleeve being of a shape and size to slide over the side wall of the vial and guide the cannula through the vial free from contact with the inner surface of the vial side wall prior to penetration of the diaphragm of said plunger.

6. The adapter of claim 5 with a removable cap to close the vial prior to its use.

7. An adapter for transferring fluid from a fluid source into a vial, the vial having a closed end, a continuous sidewall, an open end and a pierceable plunger sealingly slideable within the sidewall to define an enclosed variable volume fluid chamber with the closed end of the of the vial, the adapter comprising:

a sleeve member having an open end, a closed end and a sleeve portion having an interior surface such that the open end and interior surface of the sleeve portion telescopingly fit over the open end and sidewall of the vial;

fluid inlet means at the closed end of the sleeve member for connection to the fluid source;

a cannula coaxially extending within the sleeve member and having a first end mounted in the closed end of the sleeve member in fluid communication with the fluid inlet means and a second end axially ending within the interior surface of the sleeve portion; and

axially extending support means coaxially surrounding a portion of the cannula and extending from the closed end of the sleeve member to a truncated end axially along the cannula so that an unsurrounded portion of the cannula can penetrate the pierceable plunger when the truncated end of the support means abuts the plunger sot hat when fluid is delivered through the cannula into the variable volume fluid chamber in the vial, the plunger, the support means and the sleeve member move toward the open end of the vial.

8. The adapter of claim 7 further including radial clearance between the support means and the interior surface of the sleeve member.

9. The adapter of claim 7 wherein the support means is a plurality of axial ribs surrounding the cannula.