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Abusable substance dosage form having reduced abuse potential

  • US 5,236,714 A
  • Filed: 11/01/1988
  • Issued: 08/17/1993
  • Est. Priority Date: 11/01/1988
  • Status: Expired due to Term
First Claim
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1. A method for administering an abusable substance to the skin or mucosa to produce a predetermined beneficial effect which comprises:

  • a) contacting the skin or mucose with a composition comprising a mixture of;

    i) an amount of an abusable substance in a form that is permeable to the skin or mucosa to which it is intended to be applied; and

    ii) an abuse negating amount of at least one antagonist for said abusable substance in a form that is impermeable to the skin or mucosa to which it is to be applied; and

    b) maintaining said composition on the skin or mucosa for a period of time at least sufficient for the abusable substance to produce the beneficial effect.

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